AHR Expression Vectors, Lentivirus & CRISPR Knockout Vectors
Enhance your research with ready-to-use AHR-specific vectors and viral particles designed for reliable AHR overexpression, knockout, and silencing across a wide range of experimental systems. abm offers a complete portfolio of validated molecular tools – including AHR CRISPR knockout vectors, lentiviral particles, AAV vectors, adenovirus, ORF clones, and siRNA constructs for both in vitro and in vivo applications.
Human AHR Gene Overview
| Gene Name | aryl hydrocarbon receptor |
|---|---|
| Gene Symbol | AHR |
| Synonyms | FVH3,RP85,bHLHe76 |
| NCBI ID | 196 |
| Ensembl ID | ENSG00000106546 |
| Uniprot ID | P35869 |
| Gene Type | Protein coding |
Gene Summary
The protein encoded by this gene is a ligand-activated helix-loop-helix transcription factor involved in the regulation of biological responses to planar aromatic hydrocarbons. This receptor has been shown to regulate xenobiotic-metabolizing enzymes such as cytochrome P450. Before ligand binding, the encoded protein is sequestered in the cytoplasm; upon ligand binding, this protein moves to the nucleus and stimulates transcription of target genes. [provided by RefSeq, Sep 2015]
Human AHR Related Products
| Product Type | Key Applications | Cat. No. | Product |
|---|---|---|---|
| Lentiviral Vector & Virus | Stable overexpression | LC111561 | View Product |
| AAV Vector & Virus | Long-term expression | VC111561 | View Product |
| Adenovirus | Transient expression | A111561 | View Product |
| CRISPR KO Tools | Gene knockout (Lentiviral) | LG111561 | View Product |
| Gene knockout (non-viral) | PG111561 | View Product | |
| Gene knockout (AAV) | VG111561 | View Product | |
| CRISPR Activation | Gene activation | LA111561 | View Product |
| siRNA Tools | Gene knockdown (Lentiviral) | LS111561 | View Product |
| Gene knockdown (AAV) | VS111561 | View Product | |
| ORF Vector | Template DNA | PC111561 | View Product |
Mouse Ahr Gene Overview
| Gene Name | aryl-hydrocarbon receptor |
|---|---|
| Gene Symbol | Ahr |
| Synonyms | Ah,In,Ahh,Ahre,bHLHe76 |
| NCBI ID | 11622 |
| Ensembl ID | ENSMUSG00000019256 |
| Uniprot ID | P30561,Q8R4S5,Q8R4S6 |
| Gene Type | Protein coding |
Gene Summary
The protein encoded by this gene is a ligand-activated helix-loop-helix transcription factor involved in the regulation of biological responses to planar aromatic hydrocarbons. This receptor has been shown to regulate xenobiotic-metabolizing enzymes such as cytochrome P450. Before ligand binding, the encoded protein is sequestered in the cytoplasm; upon ligand binding, this protein moves to the nucleus and stimulates transcription of target genes. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2015]
Mouse Ahr Related Products
| Product Type | Key Applications | Cat. No. | Product |
|---|---|---|---|
| Lentiviral Vector & Virus | Stable overexpression | LC411561 | View Product |
| AAV Vector & Virus | Long-term expression | VC411561 | View Product |
| Adenovirus | Transient expression | A411561 | View Product |
| CRISPR KO Tools | Gene knockout (Lentiviral) | LG411561 | View Product |
| Gene knockout (non-viral) | PG411561 | View Product | |
| Gene knockout (AAV) | VG411561 | View Product | |
| CRISPR Activation | Gene activation | LA411561 | View Product |
| siRNA Tools | Gene knockdown (Lentiviral) | LS411561 | View Product |
| Gene knockdown (AAV) | VS411561 | View Product | |
| ORF Vector | Template DNA | PC411561 | View Product |
Rat Ahr Gene Overview
| Gene Name | aryl hydrocarbon receptor |
|---|---|
| Gene Symbol | Ahr |
| Synonyms | |
| NCBI ID | 25690 |
| Ensembl ID | ENSRNOG00000004342 |
| Uniprot ID | P41738 |
| Gene Type | Protein coding |
Gene Summary
Enables several functions, including arachidonate omega-hydroxylase activity; nuclear receptor activity; and toxic substance binding activity. Involved in several processes, including cellular response to steroid hormone stimulus; negative regulation of cell population proliferation; and regulation of macromolecule biosynthetic process. Located in cytoplasm and nucleus. Used to study hypertension; hypertrophic cardiomyopathy; pulmonary hypertension; and transient cerebral ischemia. Biomarker of hypertension and traumatic brain injury. Human ortholog(s) of this gene implicated in retinitis pigmentosa 85. Orthologous to human AHR (aryl hydrocarbon receptor). [provided by Alliance of Genome Resources, Jul 2025]
Rat Ahr Related Products
| Product Type | Key Applications | Cat. No. | Product |
|---|---|---|---|
| Lentiviral Vector & Virus | Stable overexpression | LC611561 | View Product |
| CRISPR KO Tools | Gene knockout (Lentiviral) | LG611561 | View Product |
| Gene knockout (non-viral) | PG611561 | View Product | |
| Gene knockout (AAV) | VG611561 | View Product | |
| CRISPR Activation | Gene activation | LA611561 | View Product |
| siRNA Tools | Gene knockdown (Lentiviral) | LS611561 | View Product |
| Gene knockdown (AAV) | VS611561 | View Product | |
| ORF Vector | Template DNA | PC611561 | View Product |
Accelerate Discovery with Research-Ready Constructs
| Why Researchers Choose abm | Workflow Benefits |
|---|---|
| Gene-Specific Constructs | Eliminate time-consuming cloning and accelerate project timelines |
| Available as Plasmid DNA or Packaged Virus | Choose delivery format that best fits your experiment |
| Validated Sequence Design | Ensure reliable, reproducible experimental performance |
| Available in Multiple Species Options | Simplify cross-species and translational research studies |
| Flexible Customization Services | Tailor constructs with different promoters, tags, markers and other modifications |
| Expert Technical Support | Get guidance from gene delivery specialists |
Product Overview & Key Features
| System | Applications | Key Features |
|---|---|---|
| CRISPR Knockout Vectors & Viruses | Targeted gene disruption & functional knockout studies | •Pre-designed validated sgRNAs •Available in All-in-One Cas9 + sgRNA or sgRNA-only formats •Available as lentivirus, AAV and non-viral •Ideal for stable genome editing |
| Lentiviral Expression Vectors & Particles | Stable gene overexpression or delivery into difficult-to-transfect cells | •Long-term expression through genomic integration •Highly efficient in dividing and non-dividing cells •Ideal for stable cell line generation |
| AAV Vectors & Packaged Virus | In vivo delivery & transient expression with low immunogenicity | •Multiple serotypes available for tissue targeting •Excellent for animal studies and sensitive primary cells •Episomal expression with strong safety profile |
| Adenovirus | High-efficiency transient expression | •Rapid, robust gene expression •Large cargo capacity •Ideal for primary cells and strong short-term expression studies |
| ORF Vector | Template for coding sequence | •Ready-to-use full-length coding sequences •Low cost and convenient alternative to gene synthesis |
| siRNA Knockdown Tools | Temporary gene silencing & pathway validation | •Robust gene knockdown •Ideal for target validation and preliminary functional screening •Available as Lentivirus, AAV or synthetic dsRNA oligos |