ALKBH5 Expression Vectors, Lentivirus & CRISPR Knockout Vectors
Enhance your research with ready-to-use ALKBH5-specific vectors and viral particles designed for reliable ALKBH5 overexpression, knockout, and silencing across a wide range of experimental systems. abm offers a complete portfolio of validated molecular tools – including ALKBH5 CRISPR knockout vectors, lentiviral particles, AAV vectors, adenovirus, ORF clones, and siRNA constructs for both in vitro and in vivo applications.
Human ALKBH5 Gene Overview
| Gene Name | alkB homolog 5, RNA demethylase |
|---|---|
| Gene Symbol | ALKBH5 |
| Synonyms | ABH5,OFOXD,OFOXD1 |
| NCBI ID | 54890 |
| Ensembl ID | ENSG00000091542 |
| Uniprot ID | Q6P6C2 |
| Gene Type | Protein coding |
Gene Summary
Enables mRNA N6-methyladenosine dioxygenase activity and molecular condensate scaffold activity. Involved in membraneless organelle assembly; post-transcriptional regulation of gene expression; and response to hypoxia. Acts upstream of or within regulation of mRNA export from nucleus and regulation of mRNA processing. Located in Golgi apparatus; cytosol; and nuclear speck. Is active in paraspeckles. [provided by Alliance of Genome Resources, Jul 2025]
Human ALKBH5 Related Products
| Product Type | Key Applications | Cat. No. | Product |
|---|---|---|---|
| Lentiviral Vector & Virus | Stable overexpression | LC111776 | View Product |
| AAV Vector & Virus | Long-term expression | VC111776 | View Product |
| Adenovirus | Transient expression | A111776 | View Product |
| CRISPR KO Tools | Gene knockout (Lentiviral) | LG111776 | View Product |
| Gene knockout (non-viral) | PG111776 | View Product | |
| Gene knockout (AAV) | VG111776 | View Product | |
| CRISPR Activation | Gene activation | LA111776 | View Product |
| siRNA Tools | Gene knockdown (Lentiviral) | LS111776 | View Product |
| Gene knockdown (AAV) | VS111776 | View Product | |
| ORF Vector | Template DNA | PC111776 | View Product |
Mouse Alkbh5 Gene Overview
| Gene Name | alkB homolog 5, RNA demethylase |
|---|---|
| Gene Symbol | Alkbh5 |
| Synonyms | Abh5,Ofoxd,E130207K11 |
| NCBI ID | 268420 |
| Ensembl ID | ENSMUSG00000042650 |
| Uniprot ID | Q3TSG4 |
| Gene Type | Protein coding |
Gene Summary
Enables mRNA N6-methyladenosine dioxygenase activity. Involved in mRNA destabilization and spermatogenesis. Located in nuclear speck. Is expressed in brain; intestine; and liver. Orthologous to human ALKBH5 (alkB homolog 5, RNA demethylase). [provided by Alliance of Genome Resources, Jul 2025]
Mouse Alkbh5 Related Products
| Product Type | Key Applications | Cat. No. | Product |
|---|---|---|---|
| Lentiviral Vector & Virus | Stable overexpression | LC411776 | View Product |
| AAV Vector & Virus | Long-term expression | VC411776 | View Product |
| Adenovirus | Transient expression | A411776 | View Product |
| CRISPR KO Tools | Gene knockout (Lentiviral) | LG411776 | View Product |
| Gene knockout (non-viral) | PG411776 | View Product | |
| Gene knockout (AAV) | VG411776 | View Product | |
| CRISPR Activation | Gene activation | LA411776 | View Product |
| siRNA Tools | Gene knockdown (Lentiviral) | LS411776 | View Product |
| Gene knockdown (AAV) | VS411776 | View Product | |
| ORF Vector | Template DNA | PC411776 | View Product |
Rat Alkbh5 Gene Overview
| Gene Name | alkB homolog 5, RNA demethylase |
|---|---|
| Gene Symbol | Alkbh5 |
| Synonyms | RGD1309496 |
| NCBI ID | 303193 |
| Ensembl ID | ENSRNOG00000028341 |
| Uniprot ID | D3ZKD3 |
| Gene Type | Protein coding |
Gene Summary
Predicted to enable mRNA N6-methyladenosine dioxygenase activity and molecular condensate scaffold activity. Predicted to be involved in several processes, including post-transcriptional regulation of gene expression; response to hypoxia; and spermatogenesis. Predicted to act upstream of or within regulation of mRNA export from nucleus and regulation of mRNA processing. Predicted to be located in Golgi apparatus; cytosol; and nuclear speck. Predicted to be active in paraspeckles. Orthologous to human ALKBH5 (alkB homolog 5, RNA demethylase). [provided by Alliance of Genome Resources, Jul 2025]
Rat Alkbh5 Related Products
| Product Type | Key Applications | Cat. No. | Product |
|---|---|---|---|
| Lentiviral Vector & Virus | Stable overexpression | LC611776 | View Product |
| AAV Vector & Virus | Long-term expression | VC611776 | View Product |
| Adenovirus | Transient expression | A611776 | View Product |
| ORF Vector | Template DNA | PC611776 | View Product |
Accelerate Discovery with Research-Ready Constructs
| Why Researchers Choose abm | Workflow Benefits |
|---|---|
| Gene-Specific Constructs | Eliminate time-consuming cloning and accelerate project timelines |
| Available as Plasmid DNA or Packaged Virus | Choose delivery format that best fits your experiment |
| Validated Sequence Design | Ensure reliable, reproducible experimental performance |
| Available in Multiple Species Options | Simplify cross-species and translational research studies |
| Flexible Customization Services | Tailor constructs with different promoters, tags, markers and other modifications |
| Expert Technical Support | Get guidance from gene delivery specialists |
Product Overview & Key Features
| System | Applications | Key Features |
|---|---|---|
| CRISPR Knockout Vectors & Viruses | Targeted gene disruption & functional knockout studies | •Pre-designed validated sgRNAs •Available in All-in-One Cas9 + sgRNA or sgRNA-only formats •Available as lentivirus, AAV and non-viral •Ideal for stable genome editing |
| Lentiviral Expression Vectors & Particles | Stable gene overexpression or delivery into difficult-to-transfect cells | •Long-term expression through genomic integration •Highly efficient in dividing and non-dividing cells •Ideal for stable cell line generation |
| AAV Vectors & Packaged Virus | In vivo delivery & transient expression with low immunogenicity | •Multiple serotypes available for tissue targeting •Excellent for animal studies and sensitive primary cells •Episomal expression with strong safety profile |
| Adenovirus | High-efficiency transient expression | •Rapid, robust gene expression •Large cargo capacity •Ideal for primary cells and strong short-term expression studies |
| ORF Vector | Template for coding sequence | •Ready-to-use full-length coding sequences •Low cost and convenient alternative to gene synthesis |
| siRNA Knockdown Tools | Temporary gene silencing & pathway validation | •Robust gene knockdown •Ideal for target validation and preliminary functional screening •Available as Lentivirus, AAV or synthetic dsRNA oligos |