ANO1 Expression Vectors, Lentivirus & CRISPR Knockout Vectors
Enhance your research with ready-to-use ANO1-specific vectors and viral particles designed for reliable ANO1 overexpression, knockout, and silencing across a wide range of experimental systems. abm offers a complete portfolio of validated molecular tools – including ANO1 CRISPR knockout vectors, lentiviral particles, AAV vectors, adenovirus, ORF clones, and siRNA constructs for both in vitro and in vivo applications.
Human ANO1 Gene Overview
| Gene Name | anoctamin 1 |
|---|---|
| Gene Symbol | ANO1 |
| Synonyms | DOG1,INDMS,MYMY7,TAOS2,ORAOV2,TMEM16A |
| NCBI ID | 55107 |
| Ensembl ID | ENSG00000131620 |
| Uniprot ID | Q5XXA6 |
| Gene Type | Protein coding |
Gene Summary
Enables identical protein binding activity; iodide transmembrane transporter activity; and ligand-gated monoatomic ion channel activity. Involved in several processes, including monoatomic anion transport; mucus secretion; and positive regulation of insulin secretion involved in cellular response to glucose stimulus. Located in apical plasma membrane and nucleoplasm. Implicated in Moyamoya disease. [provided by Alliance of Genome Resources, Jul 2025]
Human ANO1 Related Products
| Product Type | Key Applications | Cat. No. | Product |
|---|---|---|---|
| Lentiviral Vector & Virus | Stable overexpression | LC112037 | View Product |
| AAV Vector & Virus | Long-term expression | VC112037 | View Product |
| Adenovirus | Transient expression | A112037 | View Product |
| CRISPR KO Tools | Gene knockout (Lentiviral) | LG112037 | View Product |
| Gene knockout (non-viral) | PG112037 | View Product | |
| Gene knockout (AAV) | VG112037 | View Product | |
| CRISPR Activation | Gene activation | LA112037 | View Product |
| siRNA Tools | Gene knockdown (Lentiviral) | LS112037 | View Product |
| Gene knockdown (AAV) | VS112037 | View Product | |
| ORF Vector | Template DNA | PC112037 | View Product |
Mouse Ano1 Gene Overview
| Gene Name | anoctamin 1, calcium activated chloride channel |
|---|---|
| Gene Symbol | Ano1 |
| Synonyms | Tmem16a |
| NCBI ID | 101772 |
| Ensembl ID | ENSMUSG00000031075 |
| Uniprot ID | Q8BHY3 |
| Gene Type | Protein coding |
Gene Summary
Enables intracellularly calcium-gated chloride channel activity; protein homodimerization activity; and voltage-gated chloride channel activity. Involved in several processes, including chloride transmembrane transport; detection of temperature stimulus involved in sensory perception of pain; and mucus secretion. Acts upstream of or within establishment of localization in cell and regulation of membrane potential. Located in apical plasma membrane and external side of plasma membrane. Is active in glutamatergic synapse and presynaptic membrane. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; respiratory system; and sensory organ. Human ortholog(s) of this gene implicated in Moyamoya disease. Orthologous to human ANO1 (anoctamin 1). [provided by Alliance of Genome Resources, Jul 2025]
Mouse Ano1 Related Products
| Product Type | Key Applications | Cat. No. | Product |
|---|---|---|---|
| Lentiviral Vector & Virus | Stable overexpression | LC412037 | View Product |
| Stable overexpression | LC512037 | View Product | |
| AAV Vector & Virus | Long-term expression | VC412037 | View Product |
| Long-term expression | VC512037 | View Product | |
| Adenovirus | Transient expression | A412037 | View Product |
| Transient expression | A512037 | View Product | |
| CRISPR KO Tools | Gene knockout (Lentiviral) | LG412037 | View Product |
| Gene knockout (non-viral) | PG412037 | View Product | |
| Gene knockout (AAV) | VG412037 | View Product | |
| CRISPR Activation | Gene activation | LA412037 | View Product |
| siRNA Tools | Gene knockdown (Lentiviral) | LS412037 | View Product |
| Gene knockdown (AAV) | VS412037 | View Product | |
| ORF Vector | Template DNA | PC412037 | View Product |
| Template DNA | PC512037 | View Product |
Rat Ano1 Gene Overview
| Gene Name | anoctamin 1 |
|---|---|
| Gene Symbol | Ano1 |
| Synonyms | Tmem16a |
| NCBI ID | 309135 |
| Ensembl ID | ENSRNOG00000020865 |
| Uniprot ID | |
| Gene Type | Protein coding |
Gene Summary
Enables intracellularly calcium-gated chloride channel activity; iodide transmembrane transporter activity; and signaling receptor binding activity. Involved in cellular response to peptide; chloride transmembrane transport; and iodide transport. Predicted to be located in apical plasma membrane; external side of plasma membrane; and nucleoplasm. Predicted to be active in glutamatergic synapse and presynaptic membrane. Human ortholog(s) of this gene implicated in Moyamoya disease. Orthologous to human ANO1 (anoctamin 1). [provided by Alliance of Genome Resources, Jul 2025]
Rat Ano1 Related Products
| Product Type | Key Applications | Cat. No. | Product |
|---|---|---|---|
| Lentiviral Vector & Virus | Stable overexpression | LC612037 | View Product |
| AAV Vector & Virus | Long-term expression | VC612037 | View Product |
| Adenovirus | Transient expression | A612037 | View Product |
| CRISPR KO Tools | Gene knockout (Lentiviral) | LG612037 | View Product |
| Gene knockout (non-viral) | PG612037 | View Product | |
| Gene knockout (AAV) | VG612037 | View Product | |
| CRISPR Activation | Gene activation | LA612037 | View Product |
| siRNA Tools | Gene knockdown (Lentiviral) | LS612037 | View Product |
| Gene knockdown (AAV) | VS612037 | View Product | |
| ORF Vector | Template DNA | PC612037 | View Product |
Accelerate Discovery with Research-Ready Constructs
| Why Researchers Choose abm | Workflow Benefits |
|---|---|
| Gene-Specific Constructs | Eliminate time-consuming cloning and accelerate project timelines |
| Available as Plasmid DNA or Packaged Virus | Choose delivery format that best fits your experiment |
| Validated Sequence Design | Ensure reliable, reproducible experimental performance |
| Available in Multiple Species Options | Simplify cross-species and translational research studies |
| Flexible Customization Services | Tailor constructs with different promoters, tags, markers and other modifications |
| Expert Technical Support | Get guidance from gene delivery specialists |
Product Overview & Key Features
| System | Applications | Key Features |
|---|---|---|
| CRISPR Knockout Vectors & Viruses | Targeted gene disruption & functional knockout studies | •Pre-designed validated sgRNAs •Available in All-in-One Cas9 + sgRNA or sgRNA-only formats •Available as lentivirus, AAV and non-viral •Ideal for stable genome editing |
| Lentiviral Expression Vectors & Particles | Stable gene overexpression or delivery into difficult-to-transfect cells | •Long-term expression through genomic integration •Highly efficient in dividing and non-dividing cells •Ideal for stable cell line generation |
| AAV Vectors & Packaged Virus | In vivo delivery & transient expression with low immunogenicity | •Multiple serotypes available for tissue targeting •Excellent for animal studies and sensitive primary cells •Episomal expression with strong safety profile |
| Adenovirus | High-efficiency transient expression | •Rapid, robust gene expression •Large cargo capacity •Ideal for primary cells and strong short-term expression studies |
| ORF Vector | Template for coding sequence | •Ready-to-use full-length coding sequences •Low cost and convenient alternative to gene synthesis |
| siRNA Knockdown Tools | Temporary gene silencing & pathway validation | •Robust gene knockdown •Ideal for target validation and preliminary functional screening •Available as Lentivirus, AAV or synthetic dsRNA oligos |