ARID1A Expression Vectors, Lentivirus & CRISPR Knockout Vectors
Enhance your research with ready-to-use ARID1A-specific vectors and viral particles designed for reliable ARID1A overexpression, knockout, and silencing across a wide range of experimental systems. abm offers a complete portfolio of validated molecular tools – including ARID1A CRISPR knockout vectors, lentiviral particles, AAV vectors, adenovirus, ORF clones, and siRNA constructs for both in vitro and in vivo applications.
Human ARID1A Gene Overview
| Gene Name | AT-rich interaction domain 1A |
|---|---|
| Gene Symbol | ARID1A |
| Synonyms | ELD,B120,CSS2,OSA1,P270,hELD,BM029,MRD14,hOSA1,BAF250,C1orf4,BAF250a,SMARCF1 |
| NCBI ID | 8289 |
| Ensembl ID | ENSG00000117713 |
| Uniprot ID | O14497 |
| Gene Type | Protein coding |
Gene Summary
This gene encodes a member of the SWI/SNF family, whose members have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein is part of the large ATP-dependent chromatin remodeling complex SNF/SWI, which is required for transcriptional activation of genes normally repressed by chromatin. It possesses at least two conserved domains that could be important for its function. First, it has a DNA-binding domain that can specifically bind an AT-rich DNA sequence known to be recognized by a SNF/SWI complex at the beta-globin locus. Second, the C-terminus of the protein can stimulate glucocorticoid receptor-dependent transcriptional activation. It is thought that the protein encoded by this gene confers specificity to the SNF/SWI complex and may recruit the complex to its targets through either protein-DNA or protein-protein interactions. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Human ARID1A Related Products
| Product Type | Key Applications | Cat. No. | Product |
|---|---|---|---|
| CRISPR KO Tools | Gene knockout (Lentiviral) | LG112351 | View Product |
| Gene knockout (non-viral) | PG112351 | View Product | |
| Gene knockout (AAV) | VG112351 | View Product | |
| CRISPR Activation | Gene activation | LA112351 | View Product |
| siRNA Tools | Gene knockdown (Lentiviral) | LS112351 | View Product |
| Gene knockdown (AAV) | VS112351 | View Product | |
| ORF Vector | Template DNA | PC112351 | View Product |
Mouse Arid1a Gene Overview
| Gene Name | AT-rich interaction domain 1A |
|---|---|
| Gene Symbol | Arid1a |
| Synonyms | Osa1,BAF250,BAF250a,Smarcf1,1110030E03Rik |
| NCBI ID | 93760 |
| Ensembl ID | ENSMUSG00000007880 |
| Uniprot ID | A2BH40 |
| Gene Type | Protein coding |
Gene Summary
Enables ATP-dependent chromatin remodeler activity. Contributes to nucleosome binding activity. Acts upstream of or within several processes, including circulatory system development; embryo implantation; and embryonic morphogenesis. Located in chromatin. Part of SWI/SNF complex; nBAF complex; and npBAF complex. Is expressed in several structures, including alimentary system; brain; early conceptus; genitourinary system; and sensory organ. Used to study Coffin-Siris syndrome. Human ortholog(s) of this gene implicated in Coffin-Siris syndrome 2; breast cancer; carcinoma (multiple); gastrointestinal system cancer (multiple); and neuroblastoma. Orthologous to human ARID1A (AT-rich interaction domain 1A). [provided by Alliance of Genome Resources, Jul 2025]
Mouse Arid1a Related Products
| Product Type | Key Applications | Cat. No. | Product |
|---|---|---|---|
| CRISPR KO Tools | Gene knockout (Lentiviral) | LG412351 | View Product |
| Gene knockout (non-viral) | PG412351 | View Product | |
| Gene knockout (AAV) | VG412351 | View Product | |
| CRISPR Activation | Gene activation | LA412351 | View Product |
| siRNA Tools | Gene knockdown (Lentiviral) | LS412351 | View Product |
| Gene knockdown (AAV) | VS412351 | View Product | |
| ORF Vector | Template DNA | PC412351 | View Product |
Rat Arid1a Gene Overview
| Gene Name | AT-rich interaction domain 1A |
|---|---|
| Gene Symbol | Arid1a |
| Synonyms | |
| NCBI ID | 297867 |
| Ensembl ID | ENSRNOG00000006137 |
| Uniprot ID | |
| Gene Type | Protein coding |
Gene Summary
Predicted to enable several functions, including ATP-dependent chromatin remodeler activity; nuclear receptor binding activity; and transcription coactivator activity. Predicted to contribute to nucleosome binding activity. Predicted to be involved in nucleosome disassembly; positive regulation of DNA-templated transcription; and regulation of transcription by RNA polymerase II. Predicted to act upstream of or within several processes, including circulatory system development; embryo implantation; and embryonic morphogenesis. Predicted to be located in chromatin. Predicted to be part of SWI/SNF complex; nBAF complex; and npBAF complex. Predicted to be active in nucleoplasm. Human ortholog(s) of this gene implicated in Coffin-Siris syndrome 2; breast cancer; carcinoma (multiple); gastrointestinal system cancer (multiple); and neuroblastoma. Orthologous to human ARID1A (AT-rich interaction domain 1A). [provided by Alliance of Genome Resources, Jul 2025]
Rat Arid1a Related Products
| Product Type | Key Applications | Cat. No. | Product |
|---|
Accelerate Discovery with Research-Ready Constructs
| Why Researchers Choose abm | Workflow Benefits |
|---|---|
| Gene-Specific Constructs | Eliminate time-consuming cloning and accelerate project timelines |
| Available as Plasmid DNA or Packaged Virus | Choose delivery format that best fits your experiment |
| Validated Sequence Design | Ensure reliable, reproducible experimental performance |
| Available in Multiple Species Options | Simplify cross-species and translational research studies |
| Flexible Customization Services | Tailor constructs with different promoters, tags, markers and other modifications |
| Expert Technical Support | Get guidance from gene delivery specialists |
Product Overview & Key Features
| System | Applications | Key Features |
|---|---|---|
| CRISPR Knockout Vectors & Viruses | Targeted gene disruption & functional knockout studies | •Pre-designed validated sgRNAs •Available in All-in-One Cas9 + sgRNA or sgRNA-only formats •Available as lentivirus, AAV and non-viral •Ideal for stable genome editing |
| Lentiviral Expression Vectors & Particles | Stable gene overexpression or delivery into difficult-to-transfect cells | •Long-term expression through genomic integration •Highly efficient in dividing and non-dividing cells •Ideal for stable cell line generation |
| AAV Vectors & Packaged Virus | In vivo delivery & transient expression with low immunogenicity | •Multiple serotypes available for tissue targeting •Excellent for animal studies and sensitive primary cells •Episomal expression with strong safety profile |
| Adenovirus | High-efficiency transient expression | •Rapid, robust gene expression •Large cargo capacity •Ideal for primary cells and strong short-term expression studies |
| ORF Vector | Template for coding sequence | •Ready-to-use full-length coding sequences •Low cost and convenient alternative to gene synthesis |
| siRNA Knockdown Tools | Temporary gene silencing & pathway validation | •Robust gene knockdown •Ideal for target validation and preliminary functional screening •Available as Lentivirus, AAV or synthetic dsRNA oligos |