ATF3 Expression Vectors, Lentivirus & CRISPR Knockout Vectors
Enhance your research with ready-to-use ATF3-specific vectors and viral particles designed for reliable ATF3 overexpression, knockout, and silencing across a wide range of experimental systems. abm offers a complete portfolio of validated molecular tools – including ATF3 CRISPR knockout vectors, lentiviral particles, AAV vectors, adenovirus, ORF clones, and siRNA constructs for both in vitro and in vivo applications.
Human ATF3 Gene Overview
| Gene Name | activating transcription factor 3 |
|---|---|
| Gene Symbol | ATF3 |
| Synonyms | |
| NCBI ID | 467 |
| Ensembl ID | ENSG00000162772 |
| Uniprot ID | P18847 |
| Gene Type | Protein coding |
Gene Summary
This gene encodes a member of the mammalian activation transcription factor/cAMP responsive element-binding (CREB) protein family of transcription factors. This gene is induced by a variety of signals, including many of those encountered by cancer cells, and is involved in the complex process of cellular stress response. Multiple transcript variants encoding different isoforms have been found for this gene. It is possible that alternative splicing of this gene may be physiologically important in the regulation of target genes. [provided by RefSeq, Apr 2011]
Human ATF3 Related Products
| Product Type | Key Applications | Cat. No. | Product |
|---|---|---|---|
| Lentiviral Vector & Virus | Stable overexpression | LC212609 | View Product |
| AAV Vector & Virus | Long-term expression | VC112609 | View Product |
| Adenovirus | Transient expression | A112609 | View Product |
| CRISPR KO Tools | Gene knockout (Lentiviral) | LG112609 | View Product |
| Gene knockout (non-viral) | PG112609 | View Product | |
| Gene knockout (AAV) | VG112609 | View Product | |
| CRISPR Activation | Gene activation | LA112609 | View Product |
| siRNA Tools | Gene knockdown (Lentiviral) | LS112609 | View Product |
| Gene knockdown (AAV) | VS112609 | View Product | |
| ORF Vector | Template DNA | PC112609 | View Product |
Mouse Atf3 Gene Overview
| Gene Name | activating transcription factor 3 |
|---|---|
| Gene Symbol | Atf3 |
| Synonyms | LRG-21 |
| NCBI ID | 11910 |
| Ensembl ID | ENSMUSG00000026628 |
| Uniprot ID | Q60765 |
| Gene Type | Protein coding |
Gene Summary
Enables DNA-binding transcription repressor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in several processes, including cellular response to amino acid starvation; negative regulation of ERK1 and ERK2 cascade; and regulation of transcription by RNA polymerase II. Acts upstream of or within gluconeogenesis; negative regulation of DNA-templated transcription; and skeletal muscle cell differentiation. Located in nucleus. Is expressed in several structures, including alimentary system; cardiovascular system; central nervous system; genitourinary system; and long bone. Orthologous to human ATF3 (activating transcription factor 3). [provided by Alliance of Genome Resources, Apr 2025]
Mouse Atf3 Related Products
| Product Type | Key Applications | Cat. No. | Product |
|---|---|---|---|
| Lentiviral Vector & Virus | Stable overexpression | LC412609 | View Product |
| AAV Vector & Virus | Long-term expression | VC412609 | View Product |
| Adenovirus | Transient expression | A412609 | View Product |
| CRISPR KO Tools | Gene knockout (Lentiviral) | LG412609 | View Product |
| Gene knockout (non-viral) | PG412609 | View Product | |
| Gene knockout (AAV) | VG412609 | View Product | |
| CRISPR Activation | Gene activation | LA412609 | View Product |
| siRNA Tools | Gene knockdown (Lentiviral) | LS412609 | View Product |
| Gene knockdown (AAV) | VS412609 | View Product | |
| ORF Vector | Template DNA | PC412609 | View Product |
Rat Atf3 Gene Overview
| Gene Name | activating transcription factor 3 |
|---|---|
| Gene Symbol | Atf3 |
| Synonyms | LRFI,LRF-1 |
| NCBI ID | 25389 |
| Ensembl ID | ENSRNOG00000003745 |
| Uniprot ID | P29596 |
| Gene Type | Protein coding |
Gene Summary
Enables DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in positive regulation of cell population proliferation and positive regulation of transcription by RNA polymerase II. Predicted to be located in Golgi apparatus; microtubule organizing center; and nuclear lumen. Predicted to be part of CHOP-ATF3 complex and RNA polymerase II transcription regulator complex. Predicted to be active in nucleus. Orthologous to human ATF3 (activating transcription factor 3). [provided by Alliance of Genome Resources, Jul 2025]
Rat Atf3 Related Products
| Product Type | Key Applications | Cat. No. | Product |
|---|---|---|---|
| Lentiviral Vector & Virus | Stable overexpression | LC612609 | View Product |
| AAV Vector & Virus | Long-term expression | VC612609 | View Product |
| Adenovirus | Transient expression | A612609 | View Product |
| CRISPR KO Tools | Gene knockout (Lentiviral) | LG612609 | View Product |
| Gene knockout (non-viral) | PG612609 | View Product | |
| Gene knockout (AAV) | VG612609 | View Product | |
| CRISPR Activation | Gene activation | LA612609 | View Product |
| siRNA Tools | Gene knockdown (Lentiviral) | LS612609 | View Product |
| Gene knockdown (AAV) | VS612609 | View Product | |
| ORF Vector | Template DNA | PC612609 | View Product |
Accelerate Discovery with Research-Ready Constructs
| Why Researchers Choose abm | Workflow Benefits |
|---|---|
| Gene-Specific Constructs | Eliminate time-consuming cloning and accelerate project timelines |
| Available as Plasmid DNA or Packaged Virus | Choose delivery format that best fits your experiment |
| Validated Sequence Design | Ensure reliable, reproducible experimental performance |
| Available in Multiple Species Options | Simplify cross-species and translational research studies |
| Flexible Customization Services | Tailor constructs with different promoters, tags, markers and other modifications |
| Expert Technical Support | Get guidance from gene delivery specialists |
Product Overview & Key Features
| System | Applications | Key Features |
|---|---|---|
| CRISPR Knockout Vectors & Viruses | Targeted gene disruption & functional knockout studies | •Pre-designed validated sgRNAs •Available in All-in-One Cas9 + sgRNA or sgRNA-only formats •Available as lentivirus, AAV and non-viral •Ideal for stable genome editing |
| Lentiviral Expression Vectors & Particles | Stable gene overexpression or delivery into difficult-to-transfect cells | •Long-term expression through genomic integration •Highly efficient in dividing and non-dividing cells •Ideal for stable cell line generation |
| AAV Vectors & Packaged Virus | In vivo delivery & transient expression with low immunogenicity | •Multiple serotypes available for tissue targeting •Excellent for animal studies and sensitive primary cells •Episomal expression with strong safety profile |
| Adenovirus | High-efficiency transient expression | •Rapid, robust gene expression •Large cargo capacity •Ideal for primary cells and strong short-term expression studies |
| ORF Vector | Template for coding sequence | •Ready-to-use full-length coding sequences •Low cost and convenient alternative to gene synthesis |
| siRNA Knockdown Tools | Temporary gene silencing & pathway validation | •Robust gene knockdown •Ideal for target validation and preliminary functional screening •Available as Lentivirus, AAV or synthetic dsRNA oligos |