ATG7 Expression Vectors, Lentivirus & CRISPR Knockout Vectors
Enhance your research with ready-to-use ATG7-specific vectors and viral particles designed for reliable ATG7 overexpression, knockout, and silencing across a wide range of experimental systems. abm offers a complete portfolio of validated molecular tools – including ATG7 CRISPR knockout vectors, lentiviral particles, AAV vectors, adenovirus, ORF clones, and siRNA constructs for both in vitro and in vivo applications.
Human ATG7 Gene Overview
| Gene Name | autophagy related 7 |
|---|---|
| Gene Symbol | ATG7 |
| Synonyms | GSA7,APG7L,SCAR31,APG7-LIKE |
| NCBI ID | 10533 |
| Ensembl ID | ENSG00000197548 |
| Uniprot ID | O95352 |
| Gene Type | Protein coding |
Gene Summary
This gene encodes an E1-like activating enzyme that is essential for autophagy and cytoplasmic to vacuole transport. The encoded protein is also thought to modulate p53-dependent cell cycle pathways during prolonged metabolic stress. It has been associated with multiple functions, including axon membrane trafficking, axonal homeostasis, mitophagy, adipose differentiation, and hematopoietic stem cell maintenance. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2015]
Human ATG7 Related Products
| Product Type | Key Applications | Cat. No. | Product |
|---|---|---|---|
| Lentiviral Vector & Virus | Stable overexpression | LC112640 | View Product |
| AAV Vector & Virus | Long-term expression | VC112640 | View Product |
| Adenovirus | Transient expression | A112640 | View Product |
| CRISPR KO Tools | Gene knockout (Lentiviral) | LG112640 | View Product |
| Gene knockout (non-viral) | PG112640 | View Product | |
| Gene knockout (AAV) | VG112640 | View Product | |
| CRISPR Activation | Gene activation | LA112640 | View Product |
| siRNA Tools | Gene knockdown (Lentiviral) | LS112640 | View Product |
| Gene knockdown (AAV) | VS112640 | View Product | |
| ORF Vector | Template DNA | PC112640 | View Product |
Mouse Atg7 Gene Overview
| Gene Name | autophagy related 7 |
|---|---|
| Gene Symbol | Atg7 |
| Synonyms | Agp7,Apg7l,Atg7l,Gm21553,1810013K23Rik |
| NCBI ID | 74244 |
| Ensembl ID | ENSMUSG00000030314 |
| Uniprot ID | Q9D906 |
| Gene Type | Protein coding |
Gene Summary
This gene encodes an E1-like activating enzyme that is essential for autophagy and cytoplasmic to vacuole transport. The encoded protein is also thought to modulate p53-dependent cell cycle pathways during prolonged metabolic stress. It has been associated with multiple functions, including axon membrane trafficking, axonal homeostasis, mitophagy, adipose differentiation, and hematopoietic stem cell maintenance. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2015]
Mouse Atg7 Related Products
| Product Type | Key Applications | Cat. No. | Product |
|---|---|---|---|
| Lentiviral Vector & Virus | Stable overexpression | LC412640 | View Product |
| Stable overexpression | LC512640 | View Product | |
| AAV Vector & Virus | Long-term expression | VC412640 | View Product |
| Long-term expression | VC512640 | View Product | |
| Adenovirus | Transient expression | A412640 | View Product |
| Transient expression | A512640 | View Product | |
| CRISPR KO Tools | Gene knockout (Lentiviral) | LG412640 | View Product |
| Gene knockout (non-viral) | PG412640 | View Product | |
| Gene knockout (AAV) | VG412640 | View Product | |
| CRISPR Activation | Gene activation | LA412640 | View Product |
| siRNA Tools | Gene knockdown (Lentiviral) | LS412640 | View Product |
| Gene knockdown (AAV) | VS412640 | View Product | |
| ORF Vector | Template DNA | PC412640 | View Product |
| Template DNA | PC512640 | View Product |
Rat Atg7 Gene Overview
| Gene Name | autophagy related 7 |
|---|---|
| Gene Symbol | Atg7 |
| Synonyms | Apg7l |
| NCBI ID | 312647 |
| Ensembl ID | ENSRNOG00000007486 |
| Uniprot ID | Q641Y5 |
| Gene Type | Protein coding |
Gene Summary
Predicted to enable Atg12 activating enzyme activity; Atg8 activating enzyme activity; and protein homodimerization activity. Involved in several processes, including cellular response to morphine; negative regulation of programmed cell death; and positive regulation of macroautophagy. Located in axon. Used to study cardiac arrest; degenerative disc disease; and high grade glioma. Biomarker of artery disease (multiple); diabetic retinopathy; metabolic dysfunction-associated steatotic liver disease (multiple); neurodegenerative disease; and paraplegia. Human ortholog(s) of this gene implicated in autosomal recessive spinocerebellar ataxia 31. Orthologous to human ATG7 (autophagy related 7). [provided by Alliance of Genome Resources, Jul 2025]
Rat Atg7 Related Products
| Product Type | Key Applications | Cat. No. | Product |
|---|---|---|---|
| Lentiviral Vector & Virus | Stable overexpression | LC612640 | View Product |
| AAV Vector & Virus | Long-term expression | VC612640 | View Product |
| Adenovirus | Transient expression | A612640 | View Product |
| CRISPR KO Tools | Gene knockout (Lentiviral) | LG612640 | View Product |
| Gene knockout (non-viral) | PG612640 | View Product | |
| Gene knockout (AAV) | VG612640 | View Product | |
| CRISPR Activation | Gene activation | LA612640 | View Product |
| siRNA Tools | Gene knockdown (Lentiviral) | LS612640 | View Product |
| Gene knockdown (AAV) | VS612640 | View Product | |
| ORF Vector | Template DNA | PC612640 | View Product |
Accelerate Discovery with Research-Ready Constructs
| Why Researchers Choose abm | Workflow Benefits |
|---|---|
| Gene-Specific Constructs | Eliminate time-consuming cloning and accelerate project timelines |
| Available as Plasmid DNA or Packaged Virus | Choose delivery format that best fits your experiment |
| Validated Sequence Design | Ensure reliable, reproducible experimental performance |
| Available in Multiple Species Options | Simplify cross-species and translational research studies |
| Flexible Customization Services | Tailor constructs with different promoters, tags, markers and other modifications |
| Expert Technical Support | Get guidance from gene delivery specialists |
Product Overview & Key Features
| System | Applications | Key Features |
|---|---|---|
| CRISPR Knockout Vectors & Viruses | Targeted gene disruption & functional knockout studies | •Pre-designed validated sgRNAs •Available in All-in-One Cas9 + sgRNA or sgRNA-only formats •Available as lentivirus, AAV and non-viral •Ideal for stable genome editing |
| Lentiviral Expression Vectors & Particles | Stable gene overexpression or delivery into difficult-to-transfect cells | •Long-term expression through genomic integration •Highly efficient in dividing and non-dividing cells •Ideal for stable cell line generation |
| AAV Vectors & Packaged Virus | In vivo delivery & transient expression with low immunogenicity | •Multiple serotypes available for tissue targeting •Excellent for animal studies and sensitive primary cells •Episomal expression with strong safety profile |
| Adenovirus | High-efficiency transient expression | •Rapid, robust gene expression •Large cargo capacity •Ideal for primary cells and strong short-term expression studies |
| ORF Vector | Template for coding sequence | •Ready-to-use full-length coding sequences •Low cost and convenient alternative to gene synthesis |
| siRNA Knockdown Tools | Temporary gene silencing & pathway validation | •Robust gene knockdown •Ideal for target validation and preliminary functional screening •Available as Lentivirus, AAV or synthetic dsRNA oligos |