AXL Expression Vectors, Lentivirus & CRISPR Knockout Vectors
Enhance your research with ready-to-use AXL-specific vectors and viral particles designed for reliable AXL overexpression, knockout, and silencing across a wide range of experimental systems. abm offers a complete portfolio of validated molecular tools – including AXL CRISPR knockout vectors, lentiviral particles, AAV vectors, adenovirus, ORF clones, and siRNA constructs for both in vitro and in vivo applications.
Human AXL Gene Overview
| Gene Name | AXL receptor tyrosine kinase |
|---|---|
| Gene Symbol | AXL |
| Synonyms | ARK,UFO,AXL3,JTK11,Tyro7 |
| NCBI ID | 558 |
| Ensembl ID | ENSG00000167601 |
| Uniprot ID | P30530 |
| Gene Type | Protein coding |
Gene Summary
The protein encoded by this gene is a member of the Tyro3-Axl-Mer (TAM) receptor tyrosine kinase subfamily. The encoded protein possesses an extracellular domain which is composed of two immunoglobulin-like motifs at the N-terminal, followed by two fibronectin type-III motifs. It transduces signals from the extracellular matrix into the cytoplasm by binding to the vitamin K-dependent protein growth arrest-specific 6 (Gas6). This gene may be involved in several cellular functions including growth, migration, aggregation and anti-inflammation in multiple cell types. The encoded protein acts as a host cell receptor for multiple viruses, including Marburg, Ebola and Lassa viruses and is a candidate receptor for the SARS-CoV2 virus. [provided by RefSeq, Sep 2021]
Human AXL Related Products
| Product Type | Key Applications | Cat. No. | Product |
|---|---|---|---|
| Lentiviral Vector & Virus | Stable overexpression | LC112899 | View Product |
| AAV Vector & Virus | Long-term expression | VC112899 | View Product |
| Adenovirus | Transient expression | A112899 | View Product |
| CRISPR KO Tools | Gene knockout (Lentiviral) | LG112899 | View Product |
| Gene knockout (non-viral) | PG112899 | View Product | |
| Gene knockout (AAV) | VG112899 | View Product | |
| CRISPR Activation | Gene activation | LA112899 | View Product |
| siRNA Tools | Gene knockdown (Lentiviral) | LS112899 | View Product |
| Gene knockdown (AAV) | VS112899 | View Product | |
| ORF Vector | Template DNA | PC112899 | View Product |
Mouse Axl Gene Overview
| Gene Name | AXL receptor tyrosine kinase |
|---|---|
| Gene Symbol | Axl |
| Synonyms | Ark,Ufo,Tyro7 |
| NCBI ID | 26362 |
| Ensembl ID | ENSMUSG00000002602 |
| Uniprot ID | Q00993 |
| Gene Type | Protein coding |
Gene Summary
Predicted to enable several functions, including phosphatidylinositol 3-kinase binding activity; phosphatidylserine binding activity; and virus receptor activity. Involved in negative regulation of apoptotic process and positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction. Acts upstream of or within several processes, including negative regulation of cytokine production; nervous system development; and neutrophil clearance. Predicted to be located in several cellular components, including actin cytoskeleton; cell surface; and extracellular space. Predicted to be part of receptor complex. Predicted to be active in plasma membrane. Is expressed in several structures, including alimentary system; brain; genitourinary system; hemolymphoid system; and respiratory system. Used to study autoimmune disease. Human ortholog(s) of this gene implicated in type 2 diabetes mellitus. Orthologous to human AXL (AXL receptor tyrosine kinase). [provided by Alliance of Genome Resources, Apr 2025]
Mouse Axl Related Products
| Product Type | Key Applications | Cat. No. | Product |
|---|---|---|---|
| Lentiviral Vector & Virus | Stable overexpression | LC412899 | View Product |
| Stable overexpression | LC512899 | View Product | |
| AAV Vector & Virus | Long-term expression | VC412899 | View Product |
| Long-term expression | VC512899 | View Product | |
| Adenovirus | Transient expression | A412899 | View Product |
| Transient expression | A512899 | View Product | |
| CRISPR KO Tools | Gene knockout (Lentiviral) | LG412899 | View Product |
| Gene knockout (non-viral) | PG412899 | View Product | |
| Gene knockout (AAV) | VG412899 | View Product | |
| CRISPR Activation | Gene activation | LA412899 | View Product |
| siRNA Tools | Gene knockdown (Lentiviral) | LS412899 | View Product |
| Gene knockdown (AAV) | VS412899 | View Product | |
| ORF Vector | Template DNA | PC412899 | View Product |
| Template DNA | PC512899 | View Product |
Rat Axl Gene Overview
| Gene Name | Axl receptor tyrosine kinase |
|---|---|
| Gene Symbol | Axl |
| Synonyms | |
| NCBI ID | 308444 |
| Ensembl ID | ENSRNOG00000020716 |
| Uniprot ID | |
| Gene Type | Protein coding |
Gene Summary
Enables myosin heavy chain binding activity and phosphatidylinositol 3-kinase binding activity. Involved in several processes, including animal organ regeneration; cellular response to hydrogen peroxide; and response to axon injury. Predicted to be located in several cellular components, including actin cytoskeleton; cell surface; and extracellular space. Predicted to be part of receptor complex. Predicted to be active in plasma membrane. Used to study glomerulonephritis. Human ortholog(s) of this gene implicated in type 2 diabetes mellitus. Orthologous to human AXL (AXL receptor tyrosine kinase). [provided by Alliance of Genome Resources, Apr 2025]
Rat Axl Related Products
| Product Type | Key Applications | Cat. No. | Product |
|---|---|---|---|
| Lentiviral Vector & Virus | Stable overexpression | LC612899 | View Product |
| Stable overexpression | LC712899 | View Product | |
| AAV Vector & Virus | Long-term expression | VC612899 | View Product |
| Long-term expression | VC712899 | View Product | |
| Adenovirus | Transient expression | A612899 | View Product |
| Transient expression | A712899 | View Product | |
| CRISPR KO Tools | Gene knockout (Lentiviral) | LG612899 | View Product |
| Gene knockout (non-viral) | PG612899 | View Product | |
| Gene knockout (AAV) | VG612899 | View Product | |
| CRISPR Activation | Gene activation | LA612899 | View Product |
| siRNA Tools | Gene knockdown (Lentiviral) | LS612899 | View Product |
| Gene knockdown (AAV) | VS612899 | View Product | |
| ORF Vector | Template DNA | PC612899 | View Product |
| Template DNA | PC712899 | View Product |
Accelerate Discovery with Research-Ready Constructs
| Why Researchers Choose abm | Workflow Benefits |
|---|---|
| Gene-Specific Constructs | Eliminate time-consuming cloning and accelerate project timelines |
| Available as Plasmid DNA or Packaged Virus | Choose delivery format that best fits your experiment |
| Validated Sequence Design | Ensure reliable, reproducible experimental performance |
| Available in Multiple Species Options | Simplify cross-species and translational research studies |
| Flexible Customization Services | Tailor constructs with different promoters, tags, markers and other modifications |
| Expert Technical Support | Get guidance from gene delivery specialists |
Product Overview & Key Features
| System | Applications | Key Features |
|---|---|---|
| CRISPR Knockout Vectors & Viruses | Targeted gene disruption & functional knockout studies | •Pre-designed validated sgRNAs •Available in All-in-One Cas9 + sgRNA or sgRNA-only formats •Available as lentivirus, AAV and non-viral •Ideal for stable genome editing |
| Lentiviral Expression Vectors & Particles | Stable gene overexpression or delivery into difficult-to-transfect cells | •Long-term expression through genomic integration •Highly efficient in dividing and non-dividing cells •Ideal for stable cell line generation |
| AAV Vectors & Packaged Virus | In vivo delivery & transient expression with low immunogenicity | •Multiple serotypes available for tissue targeting •Excellent for animal studies and sensitive primary cells •Episomal expression with strong safety profile |
| Adenovirus | High-efficiency transient expression | •Rapid, robust gene expression •Large cargo capacity •Ideal for primary cells and strong short-term expression studies |
| ORF Vector | Template for coding sequence | •Ready-to-use full-length coding sequences •Low cost and convenient alternative to gene synthesis |
| siRNA Knockdown Tools | Temporary gene silencing & pathway validation | •Robust gene knockdown •Ideal for target validation and preliminary functional screening •Available as Lentivirus, AAV or synthetic dsRNA oligos |