BCL11A Expression Vectors, Lentivirus & CRISPR Knockout Vectors
Enhance your research with ready-to-use BCL11A-specific vectors and viral particles designed for reliable BCL11A overexpression, knockout, and silencing across a wide range of experimental systems. abm offers a complete portfolio of validated molecular tools – including BCL11A CRISPR knockout vectors, lentiviral particles, AAV vectors, adenovirus, ORF clones, and siRNA constructs for both in vitro and in vivo applications.
Human BCL11A Gene Overview
| Gene Name | BCL11 transcription factor A |
|---|---|
| Gene Symbol | BCL11A |
| Synonyms | EVI9,CTIP1,DILOS,ZNF856,HBFQTL5,SMARCM1 |
| NCBI ID | 53335 |
| Ensembl ID | ENSG00000119866 |
| Uniprot ID | Q9H165 |
| Gene Type | Protein coding |
Gene Summary
This gene encodes a C2H2 type zinc-finger protein by its similarity to the mouse Bcl11a/Evi9 protein. The corresponding mouse gene is a common site of retroviral integration in myeloid leukemia, and may function as a leukemia disease gene, in part, through its interaction with BCL6. During hematopoietic cell differentiation, this gene is down-regulated. It is possibly involved in lymphoma pathogenesis since translocations associated with B-cell malignancies also deregulates its expression. Multiple transcript variants encoding several different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Human BCL11A Related Products
| Product Type | Key Applications | Cat. No. | Product |
|---|---|---|---|
| Lentiviral Vector & Virus | Stable overexpression | LC113223 | View Product |
| AAV Vector & Virus | Long-term expression | VC113223 | View Product |
| Adenovirus | Transient expression | A113223 | View Product |
| CRISPR KO Tools | Gene knockout (Lentiviral) | LG113223 | View Product |
| Gene knockout (non-viral) | PG113223 | View Product | |
| Gene knockout (AAV) | VG113223 | View Product | |
| CRISPR Activation | Gene activation | LA113223 | View Product |
| siRNA Tools | Gene knockdown (Lentiviral) | LS113223 | View Product |
| Gene knockdown (AAV) | VS113223 | View Product | |
| ORF Vector | Template DNA | PC113223 | View Product |
Mouse Bcl11a Gene Overview
| Gene Name | BCL11 transcription factor A |
|---|---|
| Gene Symbol | Bcl11a |
| Synonyms | Evi9,Ctip1,Evi9a,Evi9b,Evi9c,BCL-11A,mKIAA1809,2810047E18Rik,D930021L15Rik |
| NCBI ID | 14025 |
| Ensembl ID | ENSMUSG00000000861 |
| Uniprot ID | Q9QYE3 |
| Gene Type | Protein coding |
Gene Summary
Enables transcription corepressor activity. Involved in negative regulation of transcription by RNA polymerase II and protein sumoylation. Acts upstream of or within B cell differentiation; T cell differentiation; and negative regulation of gene expression. Located in nuclear body. Part of SWI/SNF complex. Is expressed in several structures, including alimentary system; brain; genitourinary system; sensory organ; and skin. Human ortholog(s) of this gene implicated in autism spectrum disorder; beta thalassemia; schizophrenia; and sickle cell anemia. Orthologous to human BCL11A (BCL11 transcription factor A). [provided by Alliance of Genome Resources, Jul 2025]
Mouse Bcl11a Related Products
| Product Type | Key Applications | Cat. No. | Product |
|---|---|---|---|
| Lentiviral Vector & Virus | Stable overexpression | LC413223 | View Product |
| Stable overexpression | LC513223 | View Product | |
| AAV Vector & Virus | Long-term expression | VC413223 | View Product |
| Long-term expression | VC513223 | View Product | |
| Adenovirus | Transient expression | A413223 | View Product |
| Transient expression | A513223 | View Product | |
| CRISPR KO Tools | Gene knockout (Lentiviral) | LG413223 | View Product |
| Gene knockout (non-viral) | PG413223 | View Product | |
| Gene knockout (AAV) | VG413223 | View Product | |
| CRISPR Activation | Gene activation | LA413223 | View Product |
| siRNA Tools | Gene knockdown (Lentiviral) | LS413223 | View Product |
| Gene knockdown (AAV) | VS413223 | View Product | |
| ORF Vector | Template DNA | PC413223 | View Product |
| Template DNA | PC513223 | View Product |
Rat Bcl11a Gene Overview
| Gene Name | BCL11 transcription factor A |
|---|---|
| Gene Symbol | Bcl11a |
| Synonyms | |
| NCBI ID | 305589 |
| Ensembl ID | ENSRNOG00000007049 |
| Uniprot ID | |
| Gene Type | Protein coding |
Gene Summary
Enables protein kinase binding activity. Involved in several processes, including cellular response to L-glutamate; negative regulation of branching morphogenesis of a nerve; and negative regulation of dendrite development. Is active in postsynapse. Human ortholog(s) of this gene implicated in autism spectrum disorder; beta thalassemia; schizophrenia; and sickle cell anemia. Orthologous to human BCL11A (BCL11 transcription factor A). [provided by Alliance of Genome Resources, Jul 2025]
Rat Bcl11a Related Products
| Product Type | Key Applications | Cat. No. | Product |
|---|---|---|---|
| Lentiviral Vector & Virus | Stable overexpression | LC613223 | View Product |
| AAV Vector & Virus | Long-term expression | VC613223 | View Product |
| Adenovirus | Transient expression | A613223 | View Product |
| CRISPR KO Tools | Gene knockout (Lentiviral) | LG613223 | View Product |
| Gene knockout (non-viral) | PG613223 | View Product | |
| Gene knockout (AAV) | VG613223 | View Product | |
| CRISPR Activation | Gene activation | LA613223 | View Product |
| siRNA Tools | Gene knockdown (Lentiviral) | LS613223 | View Product |
| Gene knockdown (AAV) | VS613223 | View Product | |
| ORF Vector | Template DNA | PC613223 | View Product |
Accelerate Discovery with Research-Ready Constructs
| Why Researchers Choose abm | Workflow Benefits |
|---|---|
| Gene-Specific Constructs | Eliminate time-consuming cloning and accelerate project timelines |
| Available as Plasmid DNA or Packaged Virus | Choose delivery format that best fits your experiment |
| Validated Sequence Design | Ensure reliable, reproducible experimental performance |
| Available in Multiple Species Options | Simplify cross-species and translational research studies |
| Flexible Customization Services | Tailor constructs with different promoters, tags, markers and other modifications |
| Expert Technical Support | Get guidance from gene delivery specialists |
Product Overview & Key Features
| System | Applications | Key Features |
|---|---|---|
| CRISPR Knockout Vectors & Viruses | Targeted gene disruption & functional knockout studies | •Pre-designed validated sgRNAs •Available in All-in-One Cas9 + sgRNA or sgRNA-only formats •Available as lentivirus, AAV and non-viral •Ideal for stable genome editing |
| Lentiviral Expression Vectors & Particles | Stable gene overexpression or delivery into difficult-to-transfect cells | •Long-term expression through genomic integration •Highly efficient in dividing and non-dividing cells •Ideal for stable cell line generation |
| AAV Vectors & Packaged Virus | In vivo delivery & transient expression with low immunogenicity | •Multiple serotypes available for tissue targeting •Excellent for animal studies and sensitive primary cells •Episomal expression with strong safety profile |
| Adenovirus | High-efficiency transient expression | •Rapid, robust gene expression •Large cargo capacity •Ideal for primary cells and strong short-term expression studies |
| ORF Vector | Template for coding sequence | •Ready-to-use full-length coding sequences •Low cost and convenient alternative to gene synthesis |
| siRNA Knockdown Tools | Temporary gene silencing & pathway validation | •Robust gene knockdown •Ideal for target validation and preliminary functional screening •Available as Lentivirus, AAV or synthetic dsRNA oligos |