CAV1 Expression Vectors, Lentivirus & CRISPR Knockout Vectors
Enhance your research with ready-to-use CAV1-specific vectors and viral particles designed for reliable CAV1 overexpression, knockout, and silencing across a wide range of experimental systems. abm offers a complete portfolio of validated molecular tools – including CAV1 CRISPR knockout vectors, lentiviral particles, AAV vectors, adenovirus, ORF clones, and siRNA constructs for both in vitro and in vivo applications.
Human CAV1 Gene Overview
| Gene Name | caveolin 1 |
|---|---|
| Gene Symbol | CAV1 |
| Synonyms | CGL3,PPH3,BSCL3,LCCNS,VIP21,MSTP085 |
| NCBI ID | 857 |
| Ensembl ID | ENSG00000105974 |
| Uniprot ID | Q03135 |
| Gene Type | Protein coding |
Gene Summary
The scaffolding protein encoded by this gene is the main component of the caveolae plasma membranes found in most cell types. The protein links integrin subunits to the tyrosine kinase FYN, an initiating step in coupling integrins to the Ras-ERK pathway and promoting cell cycle progression. The gene is a tumor suppressor gene candidate and a negative regulator of the Ras-p42/44 mitogen-activated kinase cascade. Caveolin 1 and caveolin 2 are located next to each other on chromosome 7 and express colocalizing proteins that form a stable hetero-oligomeric complex. Mutations in this gene have been associated with Berardinelli-Seip congenital lipodystrophy. Alternatively spliced transcripts encode alpha and beta isoforms of caveolin 1.[provided by RefSeq, Mar 2010]
Human CAV1 Related Products
| Product Type | Key Applications | Cat. No. | Product |
|---|---|---|---|
| Lentiviral Vector & Virus | Stable overexpression | LC115098 | View Product |
| AAV Vector & Virus | Long-term expression | VC115098 | View Product |
| CRISPR KO Tools | Gene knockout (Lentiviral) | LG115098 | View Product |
| Gene knockout (non-viral) | PG115098 | View Product | |
| Gene knockout (AAV) | VG115098 | View Product | |
| CRISPR Activation | Gene activation | LA115098 | View Product |
| siRNA Tools | Gene knockdown (Lentiviral) | LS115098 | View Product |
| Gene knockdown (AAV) | VS115098 | View Product | |
| ORF Vector | Template DNA | PC115098 | View Product |
Mouse Cav1 Gene Overview
| Gene Name | caveolin 1, caveolae protein |
|---|---|
| Gene Symbol | Cav1 |
| Synonyms | Cav,Cav-1 |
| NCBI ID | 12389 |
| Ensembl ID | ENSMUSG00000007655 |
| Uniprot ID | P49817 |
| Gene Type | Protein coding |
Gene Summary
Enables several functions, including enzyme binding activity; oxysterol binding activity; and protein heterodimerization activity. Involved in several processes, including negative regulation of programmed cell death; regulation of heart contraction; and regulation of macromolecule metabolic process. Acts upstream of with a negative effect on lactation. Acts upstream of or within several processes, including blood vessel diameter maintenance; blood vessel morphogenesis; and negative regulation of signal transduction. Located in several cellular components, including acrosomal membrane; caveola; and perinuclear region of cytoplasm. Part of caveolar macromolecular signaling complex. Colocalizes with focal adhesion. Is expressed in several structures, including cardiovascular system; cerebral cortex; lung; paraxial mesenchyme; and tooth. Used to study Alzheimer's disease; breast cancer; and hypertrophic cardiomyopathy. Human ortholog(s) of this gene implicated in several diseases, including breast cancer (multiple); lipodystrophy (multiple); primary open angle glaucoma; primary pulmonary hypertension; and systemic scleroderma (multiple). Orthologous to human CAV1 (caveolin 1). [provided by Alliance of Genome Resources, Jul 2025]
Mouse Cav1 Related Products
| Product Type | Key Applications | Cat. No. | Product |
|---|---|---|---|
| Lentiviral Vector & Virus | Stable overexpression | LC415098 | View Product |
| Stable overexpression | LC515098 | View Product | |
| AAV Vector & Virus | Long-term expression | VC415098 | View Product |
| Long-term expression | VC515098 | View Product | |
| Adenovirus | Transient expression | A415098 | View Product |
| Transient expression | A515098 | View Product | |
| CRISPR KO Tools | Gene knockout (Lentiviral) | LG415098 | View Product |
| Gene knockout (non-viral) | PG415098 | View Product | |
| Gene knockout (AAV) | VG415098 | View Product | |
| CRISPR Activation | Gene activation | LA415098 | View Product |
| siRNA Tools | Gene knockdown (Lentiviral) | LS415098 | View Product |
| Gene knockdown (AAV) | VS415098 | View Product | |
| ORF Vector | Template DNA | PC415098 | View Product |
| Template DNA | PC515098 | View Product |
Rat Cav1 Gene Overview
| Gene Name | caveolin 1 |
|---|---|
| Gene Symbol | Cav1 |
| Synonyms | Cav |
| NCBI ID | 25404 |
| Ensembl ID | ENSRNOG00000056836 |
| Uniprot ID | P41350 |
| Gene Type | Protein coding |
Gene Summary
Enables several functions, including enzyme binding activity; syntaxin binding activity; and transmembrane transporter binding activity. Involved in several processes, including negative regulation of cation transmembrane transport; positive regulation of cellular component organization; and regulation of endothelial cell proliferation. Located in several cellular components, including basal plasma membrane; focal adhesion; and peroxisomal membrane. Part of protein-containing complex. Biomarker of several diseases, including artery disease (multiple); brain ischemia (multiple); obesity; osteoarthritis; and sciatic neuropathy. Human ortholog(s) of this gene implicated in several diseases, including breast cancer (multiple); lipodystrophy (multiple); primary open angle glaucoma; primary pulmonary hypertension; and systemic scleroderma (multiple). Orthologous to human CAV1 (caveolin 1). [provided by Alliance of Genome Resources, Jul 2025]
Rat Cav1 Related Products
| Product Type | Key Applications | Cat. No. | Product |
|---|---|---|---|
| Lentiviral Vector & Virus | Stable overexpression | LC615098 | View Product |
| Stable overexpression | LC715098 | View Product | |
| AAV Vector & Virus | Long-term expression | VC615098 | View Product |
| Long-term expression | VC715098 | View Product | |
| Adenovirus | Transient expression | A615098 | View Product |
| Transient expression | A715098 | View Product | |
| CRISPR KO Tools | Gene knockout (Lentiviral) | LG615098 | View Product |
| Gene knockout (non-viral) | PG615098 | View Product | |
| Gene knockout (AAV) | VG615098 | View Product | |
| CRISPR Activation | Gene activation | LA615098 | View Product |
| siRNA Tools | Gene knockdown (Lentiviral) | LS615098 | View Product |
| Gene knockdown (AAV) | VS615098 | View Product | |
| ORF Vector | Template DNA | PC615098 | View Product |
| Template DNA | PC715098 | View Product |
Accelerate Discovery with Research-Ready Constructs
| Why Researchers Choose abm | Workflow Benefits |
|---|---|
| Gene-Specific Constructs | Eliminate time-consuming cloning and accelerate project timelines |
| Available as Plasmid DNA or Packaged Virus | Choose delivery format that best fits your experiment |
| Validated Sequence Design | Ensure reliable, reproducible experimental performance |
| Available in Multiple Species Options | Simplify cross-species and translational research studies |
| Flexible Customization Services | Tailor constructs with different promoters, tags, markers and other modifications |
| Expert Technical Support | Get guidance from gene delivery specialists |
Product Overview & Key Features
| System | Applications | Key Features |
|---|---|---|
| CRISPR Knockout Vectors & Viruses | Targeted gene disruption & functional knockout studies | •Pre-designed validated sgRNAs •Available in All-in-One Cas9 + sgRNA or sgRNA-only formats •Available as lentivirus, AAV and non-viral •Ideal for stable genome editing |
| Lentiviral Expression Vectors & Particles | Stable gene overexpression or delivery into difficult-to-transfect cells | •Long-term expression through genomic integration •Highly efficient in dividing and non-dividing cells •Ideal for stable cell line generation |
| AAV Vectors & Packaged Virus | In vivo delivery & transient expression with low immunogenicity | •Multiple serotypes available for tissue targeting •Excellent for animal studies and sensitive primary cells •Episomal expression with strong safety profile |
| Adenovirus | High-efficiency transient expression | •Rapid, robust gene expression •Large cargo capacity •Ideal for primary cells and strong short-term expression studies |
| ORF Vector | Template for coding sequence | •Ready-to-use full-length coding sequences •Low cost and convenient alternative to gene synthesis |
| siRNA Knockdown Tools | Temporary gene silencing & pathway validation | •Robust gene knockdown •Ideal for target validation and preliminary functional screening •Available as Lentivirus, AAV or synthetic dsRNA oligos |