CCR2 Expression Vectors, Lentivirus & CRISPR Knockout Vectors
Enhance your research with ready-to-use CCR2-specific vectors and viral particles designed for reliable CCR2 overexpression, knockout, and silencing across a wide range of experimental systems. abm offers a complete portfolio of validated molecular tools – including CCR2 CRISPR knockout vectors, lentiviral particles, AAV vectors, adenovirus, ORF clones, and siRNA constructs for both in vitro and in vivo applications.
Human CCR2 Gene Overview
| Gene Name | C-C motif chemokine receptor 2 |
|---|---|
| Gene Symbol | CCR2 |
| Synonyms | CKR2,CCR-2,CCR2A,CCR2B,CD192,CKR2A,CKR2B,PCLUD,CMKBR2,MCP-1-R,CC-CKR-2 |
| NCBI ID | 729230 |
| Ensembl ID | ENSG00000121807 |
| Uniprot ID | P41597 |
| Gene Type | Protein coding |
Gene Summary
The protein encoded by this gene is a receptor for monocyte chemoattractant protein-1, a chemokine which specifically mediates monocyte chemotaxis. Monocyte chemoattractant protein-1 is involved in monocyte infiltration in inflammatory diseases such as rheumatoid arthritis as well as in the inflammatory response against tumors. The encoded protein mediates agonist-dependent calcium mobilization and inhibition of adenylyl cyclase. This protein can also be a coreceptor with CD4 for HIV-1 infection. This gene is located in the chemokine receptor gene cluster region of chromosome 3. [provided by RefSeq, Aug 2017]
Human CCR2 Related Products
| Product Type | Key Applications | Cat. No. | Product |
|---|---|---|---|
| Lentiviral Vector & Virus | Stable overexpression | LC115426 | View Product |
| AAV Vector & Virus | Long-term expression | VC115426 | View Product |
| Adenovirus | Transient expression | A115426 | View Product |
| CRISPR KO Tools | Gene knockout (Lentiviral) | LG115426 | View Product |
| Gene knockout (non-viral) | PG115426 | View Product | |
| Gene knockout (AAV) | VG115426 | View Product | |
| CRISPR Activation | Gene activation | LA115426 | View Product |
| siRNA Tools | Gene knockdown (Lentiviral) | LS115426 | View Product |
| Gene knockdown (AAV) | VS115426 | View Product | |
| ORF Vector | Template DNA | PC115426 | View Product |
Mouse Ccr2 Gene Overview
| Gene Name | C-C motif chemokine receptor 2 |
|---|---|
| Gene Symbol | Ccr2 |
| Synonyms | Ckr2,Ccr2a,Ccr2b,Ckr2a,Ckr2b,mJe-r,Cmkbr2,Cc-ckr-2 |
| NCBI ID | 12772 |
| Ensembl ID | ENSMUSG00000049103 |
| Uniprot ID | P51683 |
| Gene Type | Protein coding |
Gene Summary
Enables C-C chemokine binding activity and C-C chemokine receptor activity. Involved in several processes, including mononuclear cell migration; positive regulation of cell migration; and regulation of cytokine production. Acts upstream of or within several processes, including cellular defense response; monocyte chemotaxis; and regulation of leukocyte migration. Located in external side of plasma membrane. Is expressed in several structures, including alimentary system; brain; genitourinary system; hemolymphoid system gland; and liver and biliary system. Used to study Coronavirus infectious disease and age related macular degeneration. Human ortholog(s) of this gene implicated in several diseases, including Kawasaki disease; aggressive periodontitis; coronary artery disease (multiple); glucose metabolism disease (multiple); and uveitis (multiple). Orthologous to human CCR2 (C-C motif chemokine receptor 2). [provided by Alliance of Genome Resources, Jul 2025]
Mouse Ccr2 Related Products
| Product Type | Key Applications | Cat. No. | Product |
|---|---|---|---|
| Lentiviral Vector & Virus | Stable overexpression | LC415426 | View Product |
| AAV Vector & Virus | Long-term expression | VC415426 | View Product |
| Adenovirus | Transient expression | A415426 | View Product |
| CRISPR KO Tools | Gene knockout (Lentiviral) | LG415426 | View Product |
| Gene knockout (non-viral) | PG415426 | View Product | |
| Gene knockout (AAV) | VG415426 | View Product | |
| CRISPR Activation | Gene activation | LA415426 | View Product |
| siRNA Tools | Gene knockdown (Lentiviral) | LS415426 | View Product |
| Gene knockdown (AAV) | VS415426 | View Product | |
| ORF Vector | Template DNA | PC415426 | View Product |
Rat Ccr2 Gene Overview
| Gene Name | C-C motif chemokine receptor 2 |
|---|---|
| Gene Symbol | Ccr2 |
| Synonyms | |
| NCBI ID | 60463 |
| Ensembl ID | ENSRNOG00000063127 |
| Uniprot ID | O55193 |
| Gene Type | Protein coding |
Gene Summary
Enables identical protein binding activity. Involved in several processes, including positive regulation of tumor necrosis factor production; regulation of signal transduction; and response to hyperoxia. Located in perikaryon; perinuclear region of cytoplasm; and primary dendrite. Biomarker of demyelinating disease and periapical periodontitis. Human ortholog(s) of this gene implicated in several diseases, including Kawasaki disease; aggressive periodontitis; coronary artery disease (multiple); glucose metabolism disease (multiple); and uveitis (multiple). Orthologous to human CCR2 (C-C motif chemokine receptor 2). [provided by Alliance of Genome Resources, Apr 2025]
Rat Ccr2 Related Products
| Product Type | Key Applications | Cat. No. | Product |
|---|---|---|---|
| Lentiviral Vector & Virus | Stable overexpression | LC615426 | View Product |
| AAV Vector & Virus | Long-term expression | VC615426 | View Product |
| Adenovirus | Transient expression | A615426 | View Product |
| CRISPR KO Tools | Gene knockout (Lentiviral) | LG615426 | View Product |
| Gene knockout (non-viral) | PG615426 | View Product | |
| Gene knockout (AAV) | VG615426 | View Product | |
| CRISPR Activation | Gene activation | LA615426 | View Product |
| siRNA Tools | Gene knockdown (Lentiviral) | LS615426 | View Product |
| Gene knockdown (AAV) | VS615426 | View Product | |
| ORF Vector | Template DNA | PC615426 | View Product |
Accelerate Discovery with Research-Ready Constructs
| Why Researchers Choose abm | Workflow Benefits |
|---|---|
| Gene-Specific Constructs | Eliminate time-consuming cloning and accelerate project timelines |
| Available as Plasmid DNA or Packaged Virus | Choose delivery format that best fits your experiment |
| Validated Sequence Design | Ensure reliable, reproducible experimental performance |
| Available in Multiple Species Options | Simplify cross-species and translational research studies |
| Flexible Customization Services | Tailor constructs with different promoters, tags, markers and other modifications |
| Expert Technical Support | Get guidance from gene delivery specialists |
Product Overview & Key Features
| System | Applications | Key Features |
|---|---|---|
| CRISPR Knockout Vectors & Viruses | Targeted gene disruption & functional knockout studies | •Pre-designed validated sgRNAs •Available in All-in-One Cas9 + sgRNA or sgRNA-only formats •Available as lentivirus, AAV and non-viral •Ideal for stable genome editing |
| Lentiviral Expression Vectors & Particles | Stable gene overexpression or delivery into difficult-to-transfect cells | •Long-term expression through genomic integration •Highly efficient in dividing and non-dividing cells •Ideal for stable cell line generation |
| AAV Vectors & Packaged Virus | In vivo delivery & transient expression with low immunogenicity | •Multiple serotypes available for tissue targeting •Excellent for animal studies and sensitive primary cells •Episomal expression with strong safety profile |
| Adenovirus | High-efficiency transient expression | •Rapid, robust gene expression •Large cargo capacity •Ideal for primary cells and strong short-term expression studies |
| ORF Vector | Template for coding sequence | •Ready-to-use full-length coding sequences •Low cost and convenient alternative to gene synthesis |
| siRNA Knockdown Tools | Temporary gene silencing & pathway validation | •Robust gene knockdown •Ideal for target validation and preliminary functional screening •Available as Lentivirus, AAV or synthetic dsRNA oligos |