CCR3 Expression Vectors, Lentivirus & CRISPR Knockout Vectors
Enhance your research with ready-to-use CCR3-specific vectors and viral particles designed for reliable CCR3 overexpression, knockout, and silencing across a wide range of experimental systems. abm offers a complete portfolio of validated molecular tools – including CCR3 CRISPR knockout vectors, lentiviral particles, AAV vectors, adenovirus, ORF clones, and siRNA constructs for both in vitro and in vivo applications.
Human CCR3 Gene Overview
| Gene Name | C-C motif chemokine receptor 3 |
|---|---|
| Gene Symbol | CCR3 |
| Synonyms | CKR3,CD193,CKR 3,CMKBR3,C C CKR3,CC-CKR-3 |
| NCBI ID | 1232 |
| Ensembl ID | ENSG00000183625 |
| Uniprot ID | P51677 |
| Gene Type | Protein coding |
Gene Summary
The protein encoded by this gene is a receptor for C-C type chemokines. It belongs to family 1 of the G protein-coupled receptors. This receptor binds and responds to a variety of chemokines, including eotaxin (CCL11), eotaxin-3 (CCL26), MCP-3 (CCL7), MCP-4 (CCL13), and RANTES (CCL5). It is highly expressed in eosinophils and basophils, and is also detected in TH1 and TH2 cells, as well as in airway epithelial cells. This receptor may contribute to the accumulation and activation of eosinophils and other inflammatory cells in the allergic airway. It is also known to be an entry co-receptor for HIV-1. This gene and seven other chemokine receptor genes form a chemokine receptor gene cluster on the chromosomal region 3p21. Alternatively spliced transcript variants have been described. [provided by RefSeq, Sep 2009]
Human CCR3 Related Products
| Product Type | Key Applications | Cat. No. | Product |
|---|---|---|---|
| AAV Vector & Virus | Long-term expression | VC115427 | View Product |
| Adenovirus | Transient expression | A115427 | View Product |
| CRISPR KO Tools | Gene knockout (Lentiviral) | LG115427 | View Product |
| Gene knockout (non-viral) | PG115427 | View Product | |
| Gene knockout (AAV) | VG115427 | View Product | |
| CRISPR Activation | Gene activation | LA115427 | View Product |
| siRNA Tools | Gene knockdown (Lentiviral) | LS115427 | View Product |
| Gene knockdown (AAV) | VS115427 | View Product | |
| ORF Vector | Template DNA | PC115427 | View Product |
Mouse Ccr3 Gene Overview
| Gene Name | C-C motif chemokine receptor 3 |
|---|---|
| Gene Symbol | Ccr3 |
| Synonyms | CKR3,Cmkbr3,CC-CKR3,Cmkbr1l2 |
| NCBI ID | 12771 |
| Ensembl ID | ENSMUSG00000035448 |
| Uniprot ID | P51678 |
| Gene Type | Protein coding |
Gene Summary
Enables C-C chemokine binding activity and C-C chemokine receptor activity. Involved in positive regulation of angiogenesis and positive regulation of endothelial cell proliferation. Acts upstream of or within chemotaxis. Predicted to be located in endosome; extracellular space; and plasma membrane. Predicted to be active in cytoplasm and external side of plasma membrane. Is expressed in embryo and yolk sac. Human ortholog(s) of this gene implicated in asthma; ovary epithelial cancer; and rhinitis. Orthologous to human CCR3 (C-C motif chemokine receptor 3). [provided by Alliance of Genome Resources, Apr 2025]
Mouse Ccr3 Related Products
| Product Type | Key Applications | Cat. No. | Product |
|---|---|---|---|
| Lentiviral Vector & Virus | Stable overexpression | LC415427 | View Product |
| AAV Vector & Virus | Long-term expression | VC415427 | View Product |
| Adenovirus | Transient expression | A415427 | View Product |
| CRISPR KO Tools | Gene knockout (Lentiviral) | LG415427 | View Product |
| Gene knockout (non-viral) | PG415427 | View Product | |
| Gene knockout (AAV) | VG415427 | View Product | |
| CRISPR Activation | Gene activation | LA415427 | View Product |
| siRNA Tools | Gene knockdown (Lentiviral) | LS415427 | View Product |
| Gene knockdown (AAV) | VS415427 | View Product | |
| ORF Vector | Template DNA | PC415427 | View Product |
Rat Ccr3 Gene Overview
| Gene Name | C-C motif chemokine receptor 3 |
|---|---|
| Gene Symbol | Ccr3 |
| Synonyms | Cmkbr3 |
| NCBI ID | 117027 |
| Ensembl ID | ENSRNOG00000006736 |
| Uniprot ID | O54814 |
| Gene Type | Protein coding |
Gene Summary
Predicted to enable C-C chemokine binding activity and C-C chemokine receptor activity. Involved in ERK1 and ERK2 cascade; angioblast cell migration; and leukocyte chemotaxis. Located in endosome and extracellular space. Used to study asthma and myocardial infarction. Biomarker of rhinitis. Human ortholog(s) of this gene implicated in asthma; ovary epithelial cancer; and rhinitis. Orthologous to human CCR3 (C-C motif chemokine receptor 3). [provided by Alliance of Genome Resources, Jul 2025]
Rat Ccr3 Related Products
| Product Type | Key Applications | Cat. No. | Product |
|---|---|---|---|
| Lentiviral Vector & Virus | Stable overexpression | LC615427 | View Product |
| AAV Vector & Virus | Long-term expression | VC615427 | View Product |
| Adenovirus | Transient expression | A615427 | View Product |
| CRISPR KO Tools | Gene knockout (Lentiviral) | LG615427 | View Product |
| Gene knockout (non-viral) | PG615427 | View Product | |
| Gene knockout (AAV) | VG615427 | View Product | |
| CRISPR Activation | Gene activation | LA615427 | View Product |
| siRNA Tools | Gene knockdown (Lentiviral) | LS615427 | View Product |
| Gene knockdown (AAV) | VS615427 | View Product | |
| ORF Vector | Template DNA | PC615427 | View Product |
Accelerate Discovery with Research-Ready Constructs
| Why Researchers Choose abm | Workflow Benefits |
|---|---|
| Gene-Specific Constructs | Eliminate time-consuming cloning and accelerate project timelines |
| Available as Plasmid DNA or Packaged Virus | Choose delivery format that best fits your experiment |
| Validated Sequence Design | Ensure reliable, reproducible experimental performance |
| Available in Multiple Species Options | Simplify cross-species and translational research studies |
| Flexible Customization Services | Tailor constructs with different promoters, tags, markers and other modifications |
| Expert Technical Support | Get guidance from gene delivery specialists |
Product Overview & Key Features
| System | Applications | Key Features |
|---|---|---|
| CRISPR Knockout Vectors & Viruses | Targeted gene disruption & functional knockout studies | •Pre-designed validated sgRNAs •Available in All-in-One Cas9 + sgRNA or sgRNA-only formats •Available as lentivirus, AAV and non-viral •Ideal for stable genome editing |
| Lentiviral Expression Vectors & Particles | Stable gene overexpression or delivery into difficult-to-transfect cells | •Long-term expression through genomic integration •Highly efficient in dividing and non-dividing cells •Ideal for stable cell line generation |
| AAV Vectors & Packaged Virus | In vivo delivery & transient expression with low immunogenicity | •Multiple serotypes available for tissue targeting •Excellent for animal studies and sensitive primary cells •Episomal expression with strong safety profile |
| Adenovirus | High-efficiency transient expression | •Rapid, robust gene expression •Large cargo capacity •Ideal for primary cells and strong short-term expression studies |
| ORF Vector | Template for coding sequence | •Ready-to-use full-length coding sequences •Low cost and convenient alternative to gene synthesis |
| siRNA Knockdown Tools | Temporary gene silencing & pathway validation | •Robust gene knockdown •Ideal for target validation and preliminary functional screening •Available as Lentivirus, AAV or synthetic dsRNA oligos |