CCR7 Expression Vectors, Lentivirus & CRISPR Knockout Vectors
Enhance your research with ready-to-use CCR7-specific vectors and viral particles designed for reliable CCR7 overexpression, knockout, and silencing across a wide range of experimental systems. abm offers a complete portfolio of validated molecular tools – including CCR7 CRISPR knockout vectors, lentiviral particles, AAV vectors, adenovirus, ORF clones, and siRNA constructs for both in vitro and in vivo applications.
Human CCR7 Gene Overview
| Gene Name | C-C motif chemokine receptor 7 |
|---|---|
| Gene Symbol | CCR7 |
| Synonyms | BLR2,EBI1,CCR-7,CD197,CDw197,CMKBR7,CC-CKR-7 |
| NCBI ID | 1236 |
| Ensembl ID | ENSG00000126353 |
| Uniprot ID | P32248 |
| Gene Type | Protein coding |
Gene Summary
The protein encoded by this gene is a member of the G protein-coupled receptor family. This receptor was identified as a gene induced by the Epstein-Barr virus (EBV), and is thought to be a mediator of EBV effects on B lymphocytes. This receptor is expressed in various lymphoid tissues and activates B and T lymphocytes. It has been shown to control the migration of memory T cells to inflamed tissues, as well as stimulate dendritic cell maturation. The chemokine (C-C motif) ligand 19 (CCL19/ECL) has been reported to be a specific ligand of this receptor. Signals mediated by this receptor regulate T cell homeostasis in lymph nodes, and may also function in the activation and polarization of T cells, and in chronic inflammation pathogenesis. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Sep 2014]
Human CCR7 Related Products
| Product Type | Key Applications | Cat. No. | Product |
|---|---|---|---|
| Lentiviral Vector & Virus | Stable overexpression | LC115431 | View Product |
| AAV Vector & Virus | Long-term expression | VC115431 | View Product |
| Adenovirus | Transient expression | A115431 | View Product |
| CRISPR KO Tools | Gene knockout (Lentiviral) | LG115431 | View Product |
| Gene knockout (non-viral) | PG115431 | View Product | |
| Gene knockout (AAV) | VG115431 | View Product | |
| CRISPR Activation | Gene activation | LA115431 | View Product |
| siRNA Tools | Gene knockdown (Lentiviral) | LS115431 | View Product |
| Gene knockdown (AAV) | VS115431 | View Product | |
| ORF Vector | Template DNA | PC115431 | View Product |
Mouse Ccr7 Gene Overview
| Gene Name | C-C motif chemokine receptor 7 |
|---|---|
| Gene Symbol | Ccr7 |
| Synonyms | EBI1,CCR-7,CD197,Ebi1h,Cdw197,Cmkbr7,CC-CKR-7 |
| NCBI ID | 12775 |
| Ensembl ID | ENSMUSG00000037944 |
| Uniprot ID | P47774 |
| Gene Type | Protein coding |
Gene Summary
Enables C-C chemokine receptor activity. Involved in several processes, including positive regulation of immune response; positive regulation of leukocyte chemotaxis; and regulation of macromolecule biosynthetic process. Acts upstream of or within chemotaxis; homeostasis of number of cells; and immune response. Located in external side of plasma membrane. Is expressed in several structures, including alimentary system; central nervous system; immune system; reproductive system; and white fat. Used to study Sjogren's syndrome. Orthologous to human CCR7 (C-C motif chemokine receptor 7). [provided by Alliance of Genome Resources, Jul 2025]
Mouse Ccr7 Related Products
| Product Type | Key Applications | Cat. No. | Product |
|---|---|---|---|
| Lentiviral Vector & Virus | Stable overexpression | LC415431 | View Product |
| AAV Vector & Virus | Long-term expression | VC415431 | View Product |
| Adenovirus | Transient expression | A415431 | View Product |
| CRISPR KO Tools | Gene knockout (Lentiviral) | LG415431 | View Product |
| Gene knockout (non-viral) | PG415431 | View Product | |
| Gene knockout (AAV) | VG415431 | View Product | |
| CRISPR Activation | Gene activation | LA415431 | View Product |
| siRNA Tools | Gene knockdown (Lentiviral) | LS415431 | View Product |
| Gene knockdown (AAV) | VS415431 | View Product | |
| ORF Vector | Template DNA | PC415431 | View Product |
Rat Ccr7 Gene Overview
| Gene Name | C-C motif chemokine receptor 7 |
|---|---|
| Gene Symbol | Ccr7 |
| Synonyms | |
| NCBI ID | 287673 |
| Ensembl ID | ENSRNOG00000010665 |
| Uniprot ID | |
| Gene Type | Protein coding |
Gene Summary
Predicted to enable C-C chemokine binding activity and C-C chemokine receptor activity. Predicted to be involved in several processes, including positive regulation of immune response; positive regulation of leukocyte chemotaxis; and regulation of macromolecule biosynthetic process. Predicted to act upstream of or within chemotaxis and homeostasis of number of cells. Predicted to be located in cell surface; mitochondrion; and plasma membrane. Predicted to be active in external side of plasma membrane. Orthologous to human CCR7 (C-C motif chemokine receptor 7). [provided by Alliance of Genome Resources, Apr 2025]
Rat Ccr7 Related Products
| Product Type | Key Applications | Cat. No. | Product |
|---|---|---|---|
| Lentiviral Vector & Virus | Stable overexpression | LC615431 | View Product |
| AAV Vector & Virus | Long-term expression | VC615431 | View Product |
| Adenovirus | Transient expression | A615431 | View Product |
| CRISPR KO Tools | Gene knockout (Lentiviral) | LG615431 | View Product |
| Gene knockout (non-viral) | PG615431 | View Product | |
| Gene knockout (AAV) | VG615431 | View Product | |
| CRISPR Activation | Gene activation | LA615431 | View Product |
| siRNA Tools | Gene knockdown (Lentiviral) | LS615431 | View Product |
| Gene knockdown (AAV) | VS615431 | View Product | |
| ORF Vector | Template DNA | PC615431 | View Product |
Accelerate Discovery with Research-Ready Constructs
| Why Researchers Choose abm | Workflow Benefits |
|---|---|
| Gene-Specific Constructs | Eliminate time-consuming cloning and accelerate project timelines |
| Available as Plasmid DNA or Packaged Virus | Choose delivery format that best fits your experiment |
| Validated Sequence Design | Ensure reliable, reproducible experimental performance |
| Available in Multiple Species Options | Simplify cross-species and translational research studies |
| Flexible Customization Services | Tailor constructs with different promoters, tags, markers and other modifications |
| Expert Technical Support | Get guidance from gene delivery specialists |
Product Overview & Key Features
| System | Applications | Key Features |
|---|---|---|
| CRISPR Knockout Vectors & Viruses | Targeted gene disruption & functional knockout studies | •Pre-designed validated sgRNAs •Available in All-in-One Cas9 + sgRNA or sgRNA-only formats •Available as lentivirus, AAV and non-viral •Ideal for stable genome editing |
| Lentiviral Expression Vectors & Particles | Stable gene overexpression or delivery into difficult-to-transfect cells | •Long-term expression through genomic integration •Highly efficient in dividing and non-dividing cells •Ideal for stable cell line generation |
| AAV Vectors & Packaged Virus | In vivo delivery & transient expression with low immunogenicity | •Multiple serotypes available for tissue targeting •Excellent for animal studies and sensitive primary cells •Episomal expression with strong safety profile |
| Adenovirus | High-efficiency transient expression | •Rapid, robust gene expression •Large cargo capacity •Ideal for primary cells and strong short-term expression studies |
| ORF Vector | Template for coding sequence | •Ready-to-use full-length coding sequences •Low cost and convenient alternative to gene synthesis |
| siRNA Knockdown Tools | Temporary gene silencing & pathway validation | •Robust gene knockdown •Ideal for target validation and preliminary functional screening •Available as Lentivirus, AAV or synthetic dsRNA oligos |