CD276 Expression Vectors, Lentivirus & CRISPR Knockout Vectors
Enhance your research with ready-to-use CD276-specific vectors and viral particles designed for reliable CD276 overexpression, knockout, and silencing across a wide range of experimental systems. abm offers a complete portfolio of validated molecular tools – including CD276 CRISPR knockout vectors, lentiviral particles, AAV vectors, adenovirus, ORF clones, and siRNA constructs for both in vitro and in vivo applications.
Human CD276 Gene Overview
| Gene Name | CD276 molecule |
|---|---|
| Gene Symbol | CD276 |
| Synonyms | B7H3,B7-H3,B7RP-2,4Ig-B7-H3 |
| NCBI ID | 80381 |
| Ensembl ID | ENSG00000103855 |
| Uniprot ID | Q5ZPR3 |
| Gene Type | Protein coding |
Gene Summary
The protein encoded by this gene belongs to the immunoglobulin superfamily, and thought to participate in the regulation of T-cell-mediated immune response. Studies show that while the transcript of this gene is ubiquitously expressed in normal tissues and solid tumors, the protein is preferentially expressed only in tumor tissues. Additionally, it was observed that the 3' UTR of this transcript contains a target site for miR29 microRNA, and there is an inverse correlation between the expression of this protein and miR29 levels, suggesting regulation of expression of this gene product by miR29. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011]
Human CD276 Related Products
| Product Type | Key Applications | Cat. No. | Product |
|---|---|---|---|
| Lentiviral Vector & Virus | Stable overexpression | LC115517 | View Product |
| AAV Vector & Virus | Long-term expression | VC115517 | View Product |
| Adenovirus | Transient expression | A115517 | View Product |
| CRISPR KO Tools | Gene knockout (Lentiviral) | LG115517 | View Product |
| Gene knockout (non-viral) | PG115517 | View Product | |
| Gene knockout (AAV) | VG115517 | View Product | |
| CRISPR Activation | Gene activation | LA115517 | View Product |
| siRNA Tools | Gene knockdown (Lentiviral) | LS115517 | View Product |
| Gene knockdown (AAV) | VS115517 | View Product | |
| ORF Vector | Template DNA | PC115517 | View Product |
Mouse Cd276 Gene Overview
| Gene Name | CD276 antigen |
|---|---|
| Gene Symbol | Cd276 |
| Synonyms | B7h3,B7-H3,B7RP-2,6030411F23Rik |
| NCBI ID | 102657 |
| Ensembl ID | ENSMUSG00000035914 |
| Uniprot ID | Q8VE98 |
| Gene Type | Protein coding |
Gene Summary
Enables identical protein binding activity and signaling receptor binding activity. Acts upstream of or within several processes, including positive regulation of osteoblast differentiation; regulation of T cell proliferation; and regulation of cytokine production. Located in external side of plasma membrane. Is expressed in several structures, including embryo endoderm; genitourinary system; hemolymphoid system; liver; and musculoskeletal system. Orthologous to human CD276 (CD276 molecule). [provided by Alliance of Genome Resources, Jul 2025]
Mouse Cd276 Related Products
| Product Type | Key Applications | Cat. No. | Product |
|---|---|---|---|
| Lentiviral Vector & Virus | Stable overexpression | LC415517 | View Product |
| AAV Vector & Virus | Long-term expression | VC415517 | View Product |
| Adenovirus | Transient expression | A415517 | View Product |
| CRISPR KO Tools | Gene knockout (Lentiviral) | LG415517 | View Product |
| Gene knockout (non-viral) | PG415517 | View Product | |
| Gene knockout (AAV) | VG415517 | View Product | |
| CRISPR Activation | Gene activation | LA415517 | View Product |
| siRNA Tools | Gene knockdown (Lentiviral) | LS415517 | View Product |
| Gene knockdown (AAV) | VS415517 | View Product | |
| ORF Vector | Template DNA | PC415517 | View Product |
Rat Cd276 Gene Overview
| Gene Name | Cd276 molecule |
|---|---|
| Gene Symbol | Cd276 |
| Synonyms | B7h3,B7RP-2 |
| NCBI ID | 315716 |
| Ensembl ID | ENSRNOG00000033608 |
| Uniprot ID | Q7TPB4 |
| Gene Type | Protein coding |
Gene Summary
Predicted to enable identical protein binding activity and signaling receptor binding activity. Predicted to be involved in T cell activation; T cell receptor signaling pathway; and positive regulation of type II interferon production. Predicted to act upstream of or within several processes, including positive regulation of osteoblast differentiation; regulation of T cell proliferation; and regulation of cytokine production. Predicted to be located in membrane. Predicted to be active in external side of plasma membrane. Orthologous to human CD276 (CD276 molecule). [provided by Alliance of Genome Resources, Jul 2025]
Rat Cd276 Related Products
| Product Type | Key Applications | Cat. No. | Product |
|---|---|---|---|
| Lentiviral Vector & Virus | Stable overexpression | LC615517 | View Product |
| AAV Vector & Virus | Long-term expression | VC615517 | View Product |
| Adenovirus | Transient expression | A615517 | View Product |
| CRISPR KO Tools | Gene knockout (Lentiviral) | LG615517 | View Product |
| Gene knockout (non-viral) | PG615517 | View Product | |
| Gene knockout (AAV) | VG615517 | View Product | |
| CRISPR Activation | Gene activation | LA615517 | View Product |
| siRNA Tools | Gene knockdown (Lentiviral) | LS615517 | View Product |
| Gene knockdown (AAV) | VS615517 | View Product | |
| ORF Vector | Template DNA | PC615517 | View Product |
Accelerate Discovery with Research-Ready Constructs
| Why Researchers Choose abm | Workflow Benefits |
|---|---|
| Gene-Specific Constructs | Eliminate time-consuming cloning and accelerate project timelines |
| Available as Plasmid DNA or Packaged Virus | Choose delivery format that best fits your experiment |
| Validated Sequence Design | Ensure reliable, reproducible experimental performance |
| Available in Multiple Species Options | Simplify cross-species and translational research studies |
| Flexible Customization Services | Tailor constructs with different promoters, tags, markers and other modifications |
| Expert Technical Support | Get guidance from gene delivery specialists |
Product Overview & Key Features
| System | Applications | Key Features |
|---|---|---|
| CRISPR Knockout Vectors & Viruses | Targeted gene disruption & functional knockout studies | •Pre-designed validated sgRNAs •Available in All-in-One Cas9 + sgRNA or sgRNA-only formats •Available as lentivirus, AAV and non-viral •Ideal for stable genome editing |
| Lentiviral Expression Vectors & Particles | Stable gene overexpression or delivery into difficult-to-transfect cells | •Long-term expression through genomic integration •Highly efficient in dividing and non-dividing cells •Ideal for stable cell line generation |
| AAV Vectors & Packaged Virus | In vivo delivery & transient expression with low immunogenicity | •Multiple serotypes available for tissue targeting •Excellent for animal studies and sensitive primary cells •Episomal expression with strong safety profile |
| Adenovirus | High-efficiency transient expression | •Rapid, robust gene expression •Large cargo capacity •Ideal for primary cells and strong short-term expression studies |
| ORF Vector | Template for coding sequence | •Ready-to-use full-length coding sequences •Low cost and convenient alternative to gene synthesis |
| siRNA Knockdown Tools | Temporary gene silencing & pathway validation | •Robust gene knockdown •Ideal for target validation and preliminary functional screening •Available as Lentivirus, AAV or synthetic dsRNA oligos |