CD44 Expression Vectors, Lentivirus & CRISPR Knockout Vectors
Enhance your research with ready-to-use CD44-specific vectors and viral particles designed for reliable CD44 overexpression, knockout, and silencing across a wide range of experimental systems. abm offers a complete portfolio of validated molecular tools – including CD44 CRISPR knockout vectors, lentiviral particles, AAV vectors, adenovirus, ORF clones, and siRNA constructs for both in vitro and in vivo applications.
Human CD44 Gene Overview
| Gene Name | CD44 molecule (IN blood group) |
|---|---|
| Gene Symbol | CD44 |
| Synonyms | LHR,MC56,MDU2,MDU3,MIC4,Pgp1,CDW44,CSPG8,H-CAM,HCELL,ECM-III,HUTCH-1,HUTCH-I,ECMR-III,Hermes-1 |
| NCBI ID | 960 |
| Ensembl ID | ENSG00000026508 |
| Uniprot ID | P16070 |
| Gene Type | Protein coding |
Gene Summary
The protein encoded by this gene is a cell-surface glycoprotein involved in cell-cell interactions, cell adhesion and migration. It is a receptor for hyaluronic acid (HA) and can also interact with other ligands, such as osteopontin, collagens, and matrix metalloproteinases (MMPs). This protein participates in a wide variety of cellular functions including lymphocyte activation, recirculation and homing, hematopoiesis, and tumor metastasis. Transcripts for this gene undergo complex alternative splicing that results in many functionally distinct isoforms, however, the full length nature of some of these variants has not been determined. Alternative splicing is the basis for the structural and functional diversity of this protein, and may be related to tumor metastasis. [provided by RefSeq, Jul 2008]
Human CD44 Related Products
| Product Type | Key Applications | Cat. No. | Product |
|---|---|---|---|
| Lentiviral Vector & Virus | Stable overexpression | LC115545 | View Product |
| AAV Vector & Virus | Long-term expression | VC115545 | View Product |
| Adenovirus | Transient expression | A115545 | View Product |
| CRISPR KO Tools | Gene knockout (Lentiviral) | LG115545 | View Product |
| Gene knockout (non-viral) | PG115545 | View Product | |
| Gene knockout (AAV) | VG115545 | View Product | |
| CRISPR Activation | Gene activation | LA115545 | View Product |
| siRNA Tools | Gene knockdown (Lentiviral) | LS115545 | View Product |
| Gene knockdown (AAV) | VS115545 | View Product | |
| ORF Vector | Template DNA | PC115545 | View Product |
Mouse Cd44 Gene Overview
| Gene Name | CD44 antigen |
|---|---|
| Gene Symbol | Cd44 |
| Synonyms | Ly-24,Pgp-1,HERMES |
| NCBI ID | 12505 |
| Ensembl ID | ENSMUSG00000005087 |
| Uniprot ID | P15379 |
| Gene Type | Protein coding |
Gene Summary
Enables cargo receptor activity; hyaluronic acid binding activity; and type II transforming growth factor beta receptor binding activity. Contributes to cytokine binding activity and cytokine receptor activity. Involved in several processes, including hyaluronan catabolic process; negative regulation of T cell activation; and regulation of intracellular signal transduction. Acts upstream of or within several processes, including Wnt signaling pathway; morphogenesis of a branching epithelium; and wound healing involved in inflammatory response. Located in basolateral plasma membrane; external side of plasma membrane; and microvillus. Part of macrophage migration inhibitory factor receptor complex. Is expressed in several structures, including alimentary system; branchial arch; central nervous system; genitourinary system; and limb. Human ortholog(s) of this gene implicated in breast carcinoma (multiple); carcinoma (multiple); and prostate cancer. Orthologous to human CD44 (CD44 molecule (IN blood group)). [provided by Alliance of Genome Resources, Jul 2025]
Mouse Cd44 Related Products
| Product Type | Key Applications | Cat. No. | Product |
|---|---|---|---|
| Lentiviral Vector & Virus | Stable overexpression | LC415545 | View Product |
| Stable overexpression | LC515545 | View Product | |
| AAV Vector & Virus | Long-term expression | VC415545 | View Product |
| Long-term expression | VC515545 | View Product | |
| Adenovirus | Transient expression | A415545 | View Product |
| Transient expression | A515545 | View Product | |
| CRISPR KO Tools | Gene knockout (Lentiviral) | LG415545 | View Product |
| Gene knockout (non-viral) | PG415545 | View Product | |
| Gene knockout (AAV) | VG415545 | View Product | |
| CRISPR Activation | Gene activation | LA415545 | View Product |
| siRNA Tools | Gene knockdown (Lentiviral) | LS415545 | View Product |
| Gene knockdown (AAV) | VS415545 | View Product | |
| ORF Vector | Template DNA | PC415545 | View Product |
| Template DNA | PC515545 | View Product |
Rat Cd44 Gene Overview
| Gene Name | CD44 molecule |
|---|---|
| Gene Symbol | Cd44 |
| Synonyms | CD44A,METAA,RHAMM |
| NCBI ID | 25406 |
| Ensembl ID | ENSRNOG00000006094 |
| Uniprot ID | P26051 |
| Gene Type | Protein coding |
Gene Summary
Enables epidermal growth factor receptor binding activity; phosphoprotein binding activity; and protein kinase binding activity. Involved in several processes, including blood vessel maturation; macrophage fusion; and positive regulation of neutrophil apoptotic process. Located in apical plasma membrane; basolateral plasma membrane; and cell surface. Part of protein-containing complex. Is active in glutamatergic synapse; postsynapse; and presynapse. Biomarker of borna disease and cholestasis. Human ortholog(s) of this gene implicated in breast carcinoma (multiple); carcinoma (multiple); and prostate cancer. Orthologous to human CD44 (CD44 molecule (IN blood group)). [provided by Alliance of Genome Resources, Jul 2025]
Rat Cd44 Related Products
| Product Type | Key Applications | Cat. No. | Product |
|---|---|---|---|
| Lentiviral Vector & Virus | Stable overexpression | LC615545 | View Product |
| AAV Vector & Virus | Long-term expression | VC615545 | View Product |
| Adenovirus | Transient expression | A615545 | View Product |
| CRISPR KO Tools | Gene knockout (Lentiviral) | LG615545 | View Product |
| Gene knockout (non-viral) | PG615545 | View Product | |
| Gene knockout (AAV) | VG615545 | View Product | |
| CRISPR Activation | Gene activation | LA615545 | View Product |
| siRNA Tools | Gene knockdown (Lentiviral) | LS615545 | View Product |
| Gene knockdown (AAV) | VS615545 | View Product | |
| ORF Vector | Template DNA | PC615545 | View Product |
Accelerate Discovery with Research-Ready Constructs
| Why Researchers Choose abm | Workflow Benefits |
|---|---|
| Gene-Specific Constructs | Eliminate time-consuming cloning and accelerate project timelines |
| Available as Plasmid DNA or Packaged Virus | Choose delivery format that best fits your experiment |
| Validated Sequence Design | Ensure reliable, reproducible experimental performance |
| Available in Multiple Species Options | Simplify cross-species and translational research studies |
| Flexible Customization Services | Tailor constructs with different promoters, tags, markers and other modifications |
| Expert Technical Support | Get guidance from gene delivery specialists |
Product Overview & Key Features
| System | Applications | Key Features |
|---|---|---|
| CRISPR Knockout Vectors & Viruses | Targeted gene disruption & functional knockout studies | •Pre-designed validated sgRNAs •Available in All-in-One Cas9 + sgRNA or sgRNA-only formats •Available as lentivirus, AAV and non-viral •Ideal for stable genome editing |
| Lentiviral Expression Vectors & Particles | Stable gene overexpression or delivery into difficult-to-transfect cells | •Long-term expression through genomic integration •Highly efficient in dividing and non-dividing cells •Ideal for stable cell line generation |
| AAV Vectors & Packaged Virus | In vivo delivery & transient expression with low immunogenicity | •Multiple serotypes available for tissue targeting •Excellent for animal studies and sensitive primary cells •Episomal expression with strong safety profile |
| Adenovirus | High-efficiency transient expression | •Rapid, robust gene expression •Large cargo capacity •Ideal for primary cells and strong short-term expression studies |
| ORF Vector | Template for coding sequence | •Ready-to-use full-length coding sequences •Low cost and convenient alternative to gene synthesis |
| siRNA Knockdown Tools | Temporary gene silencing & pathway validation | •Robust gene knockdown •Ideal for target validation and preliminary functional screening •Available as Lentivirus, AAV or synthetic dsRNA oligos |