CD47 Expression Vectors, Lentivirus & CRISPR Knockout Vectors
Enhance your research with ready-to-use CD47-specific vectors and viral particles designed for reliable CD47 overexpression, knockout, and silencing across a wide range of experimental systems. abm offers a complete portfolio of validated molecular tools – including CD47 CRISPR knockout vectors, lentiviral particles, AAV vectors, adenovirus, ORF clones, and siRNA constructs for both in vitro and in vivo applications.
Human CD47 Gene Overview
| Gene Name | CD47 molecule |
|---|---|
| Gene Symbol | CD47 |
| Synonyms | IAP,OA3,MER6 |
| NCBI ID | 961 |
| Ensembl ID | ENSG00000196776 |
| Uniprot ID | Q08722 |
| Gene Type | Protein coding |
Gene Summary
This gene encodes a membrane protein, which is involved in the increase in intracellular calcium concentration that occurs upon cell adhesion to extracellular matrix. The encoded protein is also a receptor for the C-terminal cell binding domain of thrombospondin, and it may play a role in membrane transport and signal transduction. This gene has broad tissue distribution, and is reduced in expression on Rh erythrocytes. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jul 2010]
Human CD47 Related Products
| Product Type | Key Applications | Cat. No. | Product |
|---|---|---|---|
| Lentiviral Vector & Virus | Stable overexpression | LC115548 | View Product |
| AAV Vector & Virus | Long-term expression | VC115548 | View Product |
| Adenovirus | Transient expression | A115548 | View Product |
| CRISPR KO Tools | Gene knockout (Lentiviral) | LG115548 | View Product |
| Gene knockout (non-viral) | PG115548 | View Product | |
| Gene knockout (AAV) | VG115548 | View Product | |
| CRISPR Activation | Gene activation | LA115548 | View Product |
| siRNA Tools | Gene knockdown (Lentiviral) | LS115548 | View Product |
| Gene knockdown (AAV) | VS115548 | View Product | |
| ORF Vector | Template DNA | PC115548 | View Product |
Mouse Cd47 Gene Overview
| Gene Name | CD47 antigen (Rh-related antigen, integrin-associated signal transducer) |
|---|---|
| Gene Symbol | Cd47 |
| Synonyms | IAP,Itgp,9130415E20Rik,B430305P08Rik |
| NCBI ID | 16423 |
| Ensembl ID | ENSMUSG00000055447 |
| Uniprot ID | Q61735 |
| Gene Type | Protein coding |
Gene Summary
Predicted to enable protein binding activity involved in heterotypic cell-cell adhesion and thrombospondin receptor activity. Involved in positive regulation of activation-induced cell death of T cells; regulation of nitric oxide biosynthetic process; and regulation of synapse pruning. Acts upstream of or within several processes, including monocyte aggregation; opsonization; and positive regulation of phagocytosis. Located in extracellular exosome and plasma membrane. Is active in glutamatergic synapse and presynapse. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; hemolymphoid system gland; and liver and biliary system. Orthologous to human CD47 (CD47 molecule). [provided by Alliance of Genome Resources, Apr 2025]
Mouse Cd47 Related Products
| Product Type | Key Applications | Cat. No. | Product |
|---|---|---|---|
| Lentiviral Vector & Virus | Stable overexpression | LC415548 | View Product |
| AAV Vector & Virus | Long-term expression | VC415548 | View Product |
| Adenovirus | Transient expression | A415548 | View Product |
| CRISPR KO Tools | Gene knockout (Lentiviral) | LG415548 | View Product |
| Gene knockout (non-viral) | PG415548 | View Product | |
| Gene knockout (AAV) | VG415548 | View Product | |
| CRISPR Activation | Gene activation | LA415548 | View Product |
| siRNA Tools | Gene knockdown (Lentiviral) | LS415548 | View Product |
| Gene knockdown (AAV) | VS415548 | View Product | |
| ORF Vector | Template DNA | PC415548 | View Product |
Rat Cd47 Gene Overview
| Gene Name | Cd47 molecule |
|---|---|
| Gene Symbol | Cd47 |
| Synonyms | Itgp |
| NCBI ID | 29364 |
| Ensembl ID | ENSRNOG00000001964 |
| Uniprot ID | P97829 |
| Gene Type | Protein coding |
Gene Summary
Enables protein binding activity involved in heterotypic cell-cell adhesion. Involved in several processes, including cellular response to cytokine stimulus; positive regulation of monocyte extravasation; and regulation of phagocytosis. Located in cell surface. Orthologous to human CD47 (CD47 molecule). [provided by Alliance of Genome Resources, Jul 2025]
Rat Cd47 Related Products
| Product Type | Key Applications | Cat. No. | Product |
|---|---|---|---|
| Lentiviral Vector & Virus | Stable overexpression | LC615548 | View Product |
| AAV Vector & Virus | Long-term expression | VC615548 | View Product |
| Adenovirus | Transient expression | A615548 | View Product |
| CRISPR KO Tools | Gene knockout (Lentiviral) | LG615548 | View Product |
| Gene knockout (non-viral) | PG615548 | View Product | |
| Gene knockout (AAV) | VG615548 | View Product | |
| CRISPR Activation | Gene activation | LA615548 | View Product |
| siRNA Tools | Gene knockdown (Lentiviral) | LS615548 | View Product |
| Gene knockdown (AAV) | VS615548 | View Product | |
| ORF Vector | Template DNA | PC615548 | View Product |
Accelerate Discovery with Research-Ready Constructs
| Why Researchers Choose abm | Workflow Benefits |
|---|---|
| Gene-Specific Constructs | Eliminate time-consuming cloning and accelerate project timelines |
| Available as Plasmid DNA or Packaged Virus | Choose delivery format that best fits your experiment |
| Validated Sequence Design | Ensure reliable, reproducible experimental performance |
| Available in Multiple Species Options | Simplify cross-species and translational research studies |
| Flexible Customization Services | Tailor constructs with different promoters, tags, markers and other modifications |
| Expert Technical Support | Get guidance from gene delivery specialists |
Product Overview & Key Features
| System | Applications | Key Features |
|---|---|---|
| CRISPR Knockout Vectors & Viruses | Targeted gene disruption & functional knockout studies | •Pre-designed validated sgRNAs •Available in All-in-One Cas9 + sgRNA or sgRNA-only formats •Available as lentivirus, AAV and non-viral •Ideal for stable genome editing |
| Lentiviral Expression Vectors & Particles | Stable gene overexpression or delivery into difficult-to-transfect cells | •Long-term expression through genomic integration •Highly efficient in dividing and non-dividing cells •Ideal for stable cell line generation |
| AAV Vectors & Packaged Virus | In vivo delivery & transient expression with low immunogenicity | •Multiple serotypes available for tissue targeting •Excellent for animal studies and sensitive primary cells •Episomal expression with strong safety profile |
| Adenovirus | High-efficiency transient expression | •Rapid, robust gene expression •Large cargo capacity •Ideal for primary cells and strong short-term expression studies |
| ORF Vector | Template for coding sequence | •Ready-to-use full-length coding sequences •Low cost and convenient alternative to gene synthesis |
| siRNA Knockdown Tools | Temporary gene silencing & pathway validation | •Robust gene knockdown •Ideal for target validation and preliminary functional screening •Available as Lentivirus, AAV or synthetic dsRNA oligos |