CD70 Expression Vectors, Lentivirus & CRISPR Knockout Vectors
Enhance your research with ready-to-use CD70-specific vectors and viral particles designed for reliable CD70 overexpression, knockout, and silencing across a wide range of experimental systems. abm offers a complete portfolio of validated molecular tools – including CD70 CRISPR knockout vectors, lentiviral particles, AAV vectors, adenovirus, ORF clones, and siRNA constructs for both in vitro and in vivo applications.
Human CD70 Gene Overview
| Gene Name | CD70 molecule |
|---|---|
| Gene Symbol | CD70 |
| Synonyms | CD27L,LPFS3,CD27-L,CD27LG,TNFSF7,TNLG8A |
| NCBI ID | 970 |
| Ensembl ID | ENSG00000125726 |
| Uniprot ID | P32970 |
| Gene Type | Protein coding |
Gene Summary
The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for TNFRSF27/CD27. It is a surface antigen on activated, but not on resting, T and B lymphocytes. It induces proliferation of costimulated T cells, enhances the generation of cytolytic T cells, and contributes to T cell activation. This cytokine is also reported to play a role in regulating B-cell activation, cytotoxic function of natural killer cells, and immunoglobulin sythesis. [provided by RefSeq, Jul 2008]
Human CD70 Related Products
| Product Type | Key Applications | Cat. No. | Product |
|---|---|---|---|
| Lentiviral Vector & Virus | Stable overexpression | LC115564 | View Product |
| AAV Vector & Virus | Long-term expression | VC115564 | View Product |
| Adenovirus | Transient expression | A115564 | View Product |
| CRISPR KO Tools | Gene knockout (Lentiviral) | LG115564 | View Product |
| Gene knockout (non-viral) | PG115564 | View Product | |
| Gene knockout (AAV) | VG115564 | View Product | |
| CRISPR Activation | Gene activation | LA115564 | View Product |
| siRNA Tools | Gene knockdown (Lentiviral) | LS115564 | View Product |
| Gene knockdown (AAV) | VS115564 | View Product | |
| ORF Vector | Template DNA | PC115564 | View Product |
Mouse Cd70 Gene Overview
| Gene Name | CD70 antigen |
|---|---|
| Gene Symbol | Cd70 |
| Synonyms | Cd27l,CD27LG,Tnfsf7,Tnlg8a |
| NCBI ID | 21948 |
| Ensembl ID | ENSMUSG00000019489 |
| Uniprot ID | O55237 |
| Gene Type | Protein coding |
Gene Summary
Enables receptor ligand activity. Involved in T cell proliferation. Is active in plasma membrane. Is expressed in Meckel's cartilage; hip; and skeleton. Human ortholog(s) of this gene implicated in lymphoproliferative syndrome. Orthologous to human CD70 (CD70 molecule). [provided by Alliance of Genome Resources, Jul 2025]
Mouse Cd70 Related Products
| Product Type | Key Applications | Cat. No. | Product |
|---|---|---|---|
| Lentiviral Vector & Virus | Stable overexpression | LC415564 | View Product |
| AAV Vector & Virus | Long-term expression | VC415564 | View Product |
| Adenovirus | Transient expression | A415564 | View Product |
| CRISPR KO Tools | Gene knockout (Lentiviral) | LG415564 | View Product |
| Gene knockout (non-viral) | PG415564 | View Product | |
| Gene knockout (AAV) | VG415564 | View Product | |
| CRISPR Activation | Gene activation | LA415564 | View Product |
| siRNA Tools | Gene knockdown (Lentiviral) | LS415564 | View Product |
| Gene knockdown (AAV) | VS415564 | View Product | |
| ORF Vector | Template DNA | PC415564 | View Product |
Rat Cd70 Gene Overview
| Gene Name | Cd70 molecule |
|---|---|
| Gene Symbol | Cd70 |
| Synonyms | |
| NCBI ID | 301132 |
| Ensembl ID | ENSRNOG00000051015 |
| Uniprot ID | |
| Gene Type | Protein coding |
Gene Summary
Predicted to enable receptor ligand activity. Predicted to be involved in several processes, including adaptive immune memory response involving T cells and B cells; cell surface receptor signaling pathway; and lymphocyte proliferation. Predicted to be active in plasma membrane. Human ortholog(s) of this gene implicated in lymphoproliferative syndrome. Orthologous to human CD70 (CD70 molecule). [provided by Alliance of Genome Resources, Apr 2025]
Rat Cd70 Related Products
| Product Type | Key Applications | Cat. No. | Product |
|---|---|---|---|
| Lentiviral Vector & Virus | Stable overexpression | LC615564 | View Product |
| AAV Vector & Virus | Long-term expression | VC615564 | View Product |
| Adenovirus | Transient expression | A615564 | View Product |
| CRISPR KO Tools | Gene knockout (Lentiviral) | LG615564 | View Product |
| Gene knockout (non-viral) | PG615564 | View Product | |
| Gene knockout (AAV) | VG615564 | View Product | |
| CRISPR Activation | Gene activation | LA615564 | View Product |
| siRNA Tools | Gene knockdown (Lentiviral) | LS615564 | View Product |
| Gene knockdown (AAV) | VS615564 | View Product | |
| ORF Vector | Template DNA | PC615564 | View Product |
Accelerate Discovery with Research-Ready Constructs
| Why Researchers Choose abm | Workflow Benefits |
|---|---|
| Gene-Specific Constructs | Eliminate time-consuming cloning and accelerate project timelines |
| Available as Plasmid DNA or Packaged Virus | Choose delivery format that best fits your experiment |
| Validated Sequence Design | Ensure reliable, reproducible experimental performance |
| Available in Multiple Species Options | Simplify cross-species and translational research studies |
| Flexible Customization Services | Tailor constructs with different promoters, tags, markers and other modifications |
| Expert Technical Support | Get guidance from gene delivery specialists |
Product Overview & Key Features
| System | Applications | Key Features |
|---|---|---|
| CRISPR Knockout Vectors & Viruses | Targeted gene disruption & functional knockout studies | •Pre-designed validated sgRNAs •Available in All-in-One Cas9 + sgRNA or sgRNA-only formats •Available as lentivirus, AAV and non-viral •Ideal for stable genome editing |
| Lentiviral Expression Vectors & Particles | Stable gene overexpression or delivery into difficult-to-transfect cells | •Long-term expression through genomic integration •Highly efficient in dividing and non-dividing cells •Ideal for stable cell line generation |
| AAV Vectors & Packaged Virus | In vivo delivery & transient expression with low immunogenicity | •Multiple serotypes available for tissue targeting •Excellent for animal studies and sensitive primary cells •Episomal expression with strong safety profile |
| Adenovirus | High-efficiency transient expression | •Rapid, robust gene expression •Large cargo capacity •Ideal for primary cells and strong short-term expression studies |
| ORF Vector | Template for coding sequence | •Ready-to-use full-length coding sequences •Low cost and convenient alternative to gene synthesis |
| siRNA Knockdown Tools | Temporary gene silencing & pathway validation | •Robust gene knockdown •Ideal for target validation and preliminary functional screening •Available as Lentivirus, AAV or synthetic dsRNA oligos |