CLTC Expression Vectors, Lentivirus & CRISPR Knockout Vectors
Enhance your research with ready-to-use CLTC-specific vectors and viral particles designed for reliable CLTC overexpression, knockout, and silencing across a wide range of experimental systems. abm offers a complete portfolio of validated molecular tools – including CLTC CRISPR knockout vectors, lentiviral particles, AAV vectors, adenovirus, ORF clones, and siRNA constructs for both in vitro and in vivo applications.
Human CLTC Gene Overview
| Gene Name | clathrin heavy chain |
|---|---|
| Gene Symbol | CLTC |
| Synonyms | Hc,CHC,CHC17,MRD56,CLH-17,CLTCL2 |
| NCBI ID | 1213 |
| Ensembl ID | ENSG00000141367 |
| Uniprot ID | Q00610 |
| Gene Type | Protein coding |
Gene Summary
Clathrin is a major protein component of the cytoplasmic face of intracellular organelles, called coated vesicles and coated pits. These specialized organelles are involved in the intracellular trafficking of receptors and endocytosis of a variety of macromolecules. The basic subunit of the clathrin coat is composed of three heavy chains and three light chains. [provided by RefSeq, Jul 2008]
Human CLTC Related Products
| Product Type | Key Applications | Cat. No. | Product |
|---|---|---|---|
| Adenovirus | Transient expression | A116388 | View Product |
| CRISPR KO Tools | Gene knockout (Lentiviral) | LG116388 | View Product |
| Gene knockout (non-viral) | PG116388 | View Product | |
| Gene knockout (AAV) | VG116388 | View Product | |
| CRISPR Activation | Gene activation | LA116388 | View Product |
| siRNA Tools | Gene knockdown (Lentiviral) | LS116388 | View Product |
| Gene knockdown (AAV) | VS116388 | View Product | |
| ORF Vector | Template DNA | PC116388 | View Product |
Mouse Cltc Gene Overview
| Gene Name | clathrin heavy chain |
|---|---|
| Gene Symbol | Cltc |
| Synonyms | CHC,3110065L21Rik |
| NCBI ID | 67300 |
| Ensembl ID | ENSMUSG00000047126 |
| Uniprot ID | Q68FD5 |
| Gene Type | Protein coding |
Gene Summary
Enables protein kinase binding activity. Predicted to be involved in several processes, including amyloid-beta clearance by transcytosis; endocytosis; and negative regulation of hyaluronan biosynthetic process. Predicted to act upstream of or within mitotic spindle assembly. Located in clathrin-coated pit. Part of membrane coat. Is active in several cellular components, including photoreceptor ribbon synapse; postsynaptic endocytic zone; and presynaptic endocytic zone membrane. Is expressed in several structures, including brain; early embryo; placenta; and unsegmented mesenchyme. Human ortholog(s) of this gene implicated in autosomal dominant intellectual developmental disorder 56. Orthologous to human CLTC (clathrin heavy chain). [provided by Alliance of Genome Resources, Jul 2025]
Mouse Cltc Related Products
| Product Type | Key Applications | Cat. No. | Product |
|---|---|---|---|
| Adenovirus | Transient expression | A416388 | View Product |
| CRISPR KO Tools | Gene knockout (Lentiviral) | LG416388 | View Product |
| Gene knockout (non-viral) | PG416388 | View Product | |
| Gene knockout (AAV) | VG416388 | View Product | |
| CRISPR Activation | Gene activation | LA416388 | View Product |
| siRNA Tools | Gene knockdown (Lentiviral) | LS416388 | View Product |
| Gene knockdown (AAV) | VS416388 | View Product | |
| ORF Vector | Template DNA | PC416388 | View Product |
Rat Cltc Gene Overview
| Gene Name | clathrin heavy chain |
|---|---|
| Gene Symbol | Cltc |
| Synonyms | |
| NCBI ID | 54241 |
| Ensembl ID | ENSRNOG00000004291 |
| Uniprot ID | P11442 |
| Gene Type | Protein coding |
Gene Summary
Enables several functions, including ankyrin binding activity; heat shock protein binding activity; and protein serine/threonine kinase binding activity. Involved in Golgi organization; endocytosis; and mitotic cell cycle. Located in T-tubule and spindle. Part of clathrin coat. Is extrinsic component of synaptic vesicle membrane. Human ortholog(s) of this gene implicated in autosomal dominant intellectual developmental disorder 56. Orthologous to human CLTC (clathrin heavy chain). [provided by Alliance of Genome Resources, Jul 2025]
Rat Cltc Related Products
| Product Type | Key Applications | Cat. No. | Product |
|---|---|---|---|
| Adenovirus | Transient expression | A616388 | View Product |
| CRISPR KO Tools | Gene knockout (Lentiviral) | LG616388 | View Product |
| Gene knockout (non-viral) | PG616388 | View Product | |
| Gene knockout (AAV) | VG616388 | View Product | |
| CRISPR Activation | Gene activation | LA616388 | View Product |
| siRNA Tools | Gene knockdown (Lentiviral) | LS616388 | View Product |
| Gene knockdown (AAV) | VS616388 | View Product | |
| ORF Vector | Template DNA | PC616388 | View Product |
Accelerate Discovery with Research-Ready Constructs
| Why Researchers Choose abm | Workflow Benefits |
|---|---|
| Gene-Specific Constructs | Eliminate time-consuming cloning and accelerate project timelines |
| Available as Plasmid DNA or Packaged Virus | Choose delivery format that best fits your experiment |
| Validated Sequence Design | Ensure reliable, reproducible experimental performance |
| Available in Multiple Species Options | Simplify cross-species and translational research studies |
| Flexible Customization Services | Tailor constructs with different promoters, tags, markers and other modifications |
| Expert Technical Support | Get guidance from gene delivery specialists |
Product Overview & Key Features
| System | Applications | Key Features |
|---|---|---|
| CRISPR Knockout Vectors & Viruses | Targeted gene disruption & functional knockout studies | •Pre-designed validated sgRNAs •Available in All-in-One Cas9 + sgRNA or sgRNA-only formats •Available as lentivirus, AAV and non-viral •Ideal for stable genome editing |
| Lentiviral Expression Vectors & Particles | Stable gene overexpression or delivery into difficult-to-transfect cells | •Long-term expression through genomic integration •Highly efficient in dividing and non-dividing cells •Ideal for stable cell line generation |
| AAV Vectors & Packaged Virus | In vivo delivery & transient expression with low immunogenicity | •Multiple serotypes available for tissue targeting •Excellent for animal studies and sensitive primary cells •Episomal expression with strong safety profile |
| Adenovirus | High-efficiency transient expression | •Rapid, robust gene expression •Large cargo capacity •Ideal for primary cells and strong short-term expression studies |
| ORF Vector | Template for coding sequence | •Ready-to-use full-length coding sequences •Low cost and convenient alternative to gene synthesis |
| siRNA Knockdown Tools | Temporary gene silencing & pathway validation | •Robust gene knockdown •Ideal for target validation and preliminary functional screening •Available as Lentivirus, AAV or synthetic dsRNA oligos |