CSF2 Expression Vectors, Lentivirus & CRISPR Knockout Vectors
Enhance your research with ready-to-use CSF2-specific vectors and viral particles designed for reliable CSF2 overexpression, knockout, and silencing across a wide range of experimental systems. abm offers a complete portfolio of validated molecular tools – including CSF2 CRISPR knockout vectors, lentiviral particles, AAV vectors, adenovirus, ORF clones, and siRNA constructs for both in vitro and in vivo applications.
Human CSF2 Gene Overview
| Gene Name | colony stimulating factor 2 |
|---|---|
| Gene Symbol | CSF2 |
| Synonyms | CSF,GMCSF |
| NCBI ID | 1437 |
| Ensembl ID | ENSG00000164400 |
| Uniprot ID | P04141 |
| Gene Type | Protein coding |
Gene Summary
The protein encoded by this gene is a cytokine that controls the production, differentiation, and function of granulocytes and macrophages. The active form of the protein is found extracellularly as a homodimer. This gene has been localized to a cluster of related genes at chromosome region 5q31, which is known to be associated with interstitial deletions in the 5q- syndrome and acute myelogenous leukemia. Other genes in the cluster include those encoding interleukins 4, 5, and 13. This gene plays a role in promoting tissue inflammation. Elevated levels of cytokines, including the one produced by this gene, have been detected in SARS-CoV-2 infected patients that develop acute respiratory distress syndrome. Mice deficient in this gene or its receptor develop pulmonary alveolar proteinosis. [provided by RefSeq, Aug 2020]
Human CSF2 Related Products
| Product Type | Key Applications | Cat. No. | Product |
|---|---|---|---|
| Lentiviral Vector & Virus | Stable overexpression | LC116914 | View Product |
| AAV Vector & Virus | Long-term expression | VC116914 | View Product |
| Adenovirus | Transient expression | A116914 | View Product |
| CRISPR KO Tools | Gene knockout (Lentiviral) | LG116914 | View Product |
| Gene knockout (non-viral) | PG116914 | View Product | |
| Gene knockout (AAV) | VG116914 | View Product | |
| CRISPR Activation | Gene activation | LA116914 | View Product |
| siRNA Tools | Gene knockdown (Lentiviral) | LS116914 | View Product |
| Gene knockdown (AAV) | VS116914 | View Product | |
| ORF Vector | Template DNA | PC116914 | View Product |
Mouse Csf2 Gene Overview
| Gene Name | colony stimulating factor 2 (granulocyte-macrophage) |
|---|---|
| Gene Symbol | Csf2 |
| Synonyms | CSF,Csfgm,GMCSF,Gm-CSf,MGI-IGM |
| NCBI ID | 12981 |
| Ensembl ID | ENSMUSG00000018916 |
| Uniprot ID | P01587 |
| Gene Type | Protein coding |
Gene Summary
Enables cytokine activity. Acts upstream of or within several processes, including embryonic placenta development; myeloid leukocyte differentiation; and positive regulation of cell population proliferation. Located in extracellular space. Is expressed in several structures, including genitourinary system; hemolymphoid system; liver; lung; and trophectoderm. Used to study pulmonary alveolar proteinosis. Human ortholog(s) of this gene implicated in acute myeloid leukemia; juvenile myelomonocytic leukemia; neutropenia; pulmonary alveolar proteinosis; and visceral leishmaniasis. Orthologous to human CSF2 (colony stimulating factor 2). [provided by Alliance of Genome Resources, Jul 2025]
Mouse Csf2 Related Products
| Product Type | Key Applications | Cat. No. | Product |
|---|---|---|---|
| Lentiviral Vector & Virus | Stable overexpression | LC416914 | View Product |
| AAV Vector & Virus | Long-term expression | VC416914 | View Product |
| Adenovirus | Transient expression | A416914 | View Product |
| CRISPR KO Tools | Gene knockout (Lentiviral) | LG416914 | View Product |
| Gene knockout (non-viral) | PG416914 | View Product | |
| Gene knockout (AAV) | VG416914 | View Product | |
| CRISPR Activation | Gene activation | LA416914 | View Product |
| siRNA Tools | Gene knockdown (Lentiviral) | LS416914 | View Product |
| Gene knockdown (AAV) | VS416914 | View Product | |
| ORF Vector | Template DNA | PC416914 | View Product |
Rat Csf2 Gene Overview
| Gene Name | colony stimulating factor 2 |
|---|---|
| Gene Symbol | Csf2 |
| Synonyms | Gmcsf,Gm-csf |
| NCBI ID | 116630 |
| Ensembl ID | ENSRNOG00000026805 |
| Uniprot ID | P48750 |
| Gene Type | Protein coding |
Gene Summary
Enables cytokine activity. Involved in several processes, including cellular response to lipopolysaccharide; epithelial fluid transport; and response to silicon dioxide. Located in extracellular space. Used to study Parkinsonism and myocardial infarction. Biomarker of abdominal aortic aneurysm; interstitial cystitis; and lung disease (multiple). Human ortholog(s) of this gene implicated in acute myeloid leukemia; juvenile myelomonocytic leukemia; neutropenia; pulmonary alveolar proteinosis; and visceral leishmaniasis. Orthologous to human CSF2 (colony stimulating factor 2). [provided by Alliance of Genome Resources, Jul 2025]
Rat Csf2 Related Products
| Product Type | Key Applications | Cat. No. | Product |
|---|
Accelerate Discovery with Research-Ready Constructs
| Why Researchers Choose abm | Workflow Benefits |
|---|---|
| Gene-Specific Constructs | Eliminate time-consuming cloning and accelerate project timelines |
| Available as Plasmid DNA or Packaged Virus | Choose delivery format that best fits your experiment |
| Validated Sequence Design | Ensure reliable, reproducible experimental performance |
| Available in Multiple Species Options | Simplify cross-species and translational research studies |
| Flexible Customization Services | Tailor constructs with different promoters, tags, markers and other modifications |
| Expert Technical Support | Get guidance from gene delivery specialists |
Product Overview & Key Features
| System | Applications | Key Features |
|---|---|---|
| CRISPR Knockout Vectors & Viruses | Targeted gene disruption & functional knockout studies | •Pre-designed validated sgRNAs •Available in All-in-One Cas9 + sgRNA or sgRNA-only formats •Available as lentivirus, AAV and non-viral •Ideal for stable genome editing |
| Lentiviral Expression Vectors & Particles | Stable gene overexpression or delivery into difficult-to-transfect cells | •Long-term expression through genomic integration •Highly efficient in dividing and non-dividing cells •Ideal for stable cell line generation |
| AAV Vectors & Packaged Virus | In vivo delivery & transient expression with low immunogenicity | •Multiple serotypes available for tissue targeting •Excellent for animal studies and sensitive primary cells •Episomal expression with strong safety profile |
| Adenovirus | High-efficiency transient expression | •Rapid, robust gene expression •Large cargo capacity •Ideal for primary cells and strong short-term expression studies |
| ORF Vector | Template for coding sequence | •Ready-to-use full-length coding sequences •Low cost and convenient alternative to gene synthesis |
| siRNA Knockdown Tools | Temporary gene silencing & pathway validation | •Robust gene knockdown •Ideal for target validation and preliminary functional screening •Available as Lentivirus, AAV or synthetic dsRNA oligos |