CX3CR1 Expression Vectors, Lentivirus & CRISPR Knockout Vectors
Enhance your research with ready-to-use CX3CR1-specific vectors and viral particles designed for reliable CX3CR1 overexpression, knockout, and silencing across a wide range of experimental systems. abm offers a complete portfolio of validated molecular tools – including CX3CR1 CRISPR knockout vectors, lentiviral particles, AAV vectors, adenovirus, ORF clones, and siRNA constructs for both in vitro and in vivo applications.
Human CX3CR1 Gene Overview
| Gene Name | C-X3-C motif chemokine receptor 1 |
|---|---|
| Gene Symbol | CX3CR1 |
| Synonyms | V28,CCRL1,GPR13,CMKDR1,GPRV28,CMKBRL1 |
| NCBI ID | 1524 |
| Ensembl ID | ENSG00000168329 |
| Uniprot ID | P49238 |
| Gene Type | Protein coding |
Gene Summary
Fractalkine is a transmembrane protein and chemokine involved in the adhesion and migration of leukocytes. The protein encoded by this gene is a receptor for fractalkine. The encoded protein also is a coreceptor for HIV-1, and some variations in this gene lead to increased susceptibility to HIV-1 infection and rapid progression to AIDS. Four transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jan 2010]
Human CX3CR1 Related Products
| Product Type | Key Applications | Cat. No. | Product |
|---|---|---|---|
| Lentiviral Vector & Virus | Stable overexpression | LC117158 | View Product |
| AAV Vector & Virus | Long-term expression | VC117158 | View Product |
| Adenovirus | Transient expression | A117158 | View Product |
| CRISPR KO Tools | Gene knockout (Lentiviral) | LG117158 | View Product |
| Gene knockout (non-viral) | PG117158 | View Product | |
| Gene knockout (AAV) | VG117158 | View Product | |
| CRISPR Activation | Gene activation | LA117158 | View Product |
| siRNA Tools | Gene knockdown (Lentiviral) | LS117158 | View Product |
| Gene knockdown (AAV) | VS117158 | View Product | |
| ORF Vector | Template DNA | PC117158 | View Product |
Mouse Cx3cr1 Gene Overview
| Gene Name | C-X3-C motif chemokine receptor 1 |
|---|---|
| Gene Symbol | Cx3cr1 |
| Synonyms | mCX3CR1 |
| NCBI ID | 13051 |
| Ensembl ID | ENSMUSG00000052336 |
| Uniprot ID | Q9Z0D9 |
| Gene Type | Protein coding |
Gene Summary
Enables C-X3-C chemokine binding activity and C-X3-C chemokine receptor activity. Involved in several processes, including antifungal innate immune response; central nervous system development; and synapse organization. Located in cell surface. Is expressed in several structures, including brain; colon; genitourinary system; head mesenchyme; and meninges. Used to study age related macular degeneration 12. Human ortholog(s) of this gene implicated in several diseases, including human immunodeficiency virus infectious disease; obesity; pulmonary hypertension; retinal disease (multiple); and systemic scleroderma. Orthologous to human CX3CR1 (C-X3-C motif chemokine receptor 1). [provided by Alliance of Genome Resources, Jul 2025]
Mouse Cx3cr1 Related Products
| Product Type | Key Applications | Cat. No. | Product |
|---|---|---|---|
| Lentiviral Vector & Virus | Stable overexpression | LC417158 | View Product |
| AAV Vector & Virus | Long-term expression | VC417158 | View Product |
| Adenovirus | Transient expression | A417158 | View Product |
| CRISPR KO Tools | Gene knockout (Lentiviral) | LG417158 | View Product |
| Gene knockout (non-viral) | PG417158 | View Product | |
| Gene knockout (AAV) | VG417158 | View Product | |
| CRISPR Activation | Gene activation | LA417158 | View Product |
| siRNA Tools | Gene knockdown (Lentiviral) | LS417158 | View Product |
| Gene knockdown (AAV) | VS417158 | View Product | |
| ORF Vector | Template DNA | PC417158 | View Product |
Rat Cx3cr1 Gene Overview
| Gene Name | C-X3-C motif chemokine receptor 1 |
|---|---|
| Gene Symbol | Cx3cr1 |
| Synonyms | Rbs11 |
| NCBI ID | 171056 |
| Ensembl ID | ENSRNOG00000018509 |
| Uniprot ID | P35411 |
| Gene Type | Protein coding |
Gene Summary
Enables C-X3-C chemokine receptor activity. Involved in several processes, including cellular response to cytokine stimulus; regulation of cell migration; and regulation of signal transduction. Located in several cellular components, including cell surface; neuronal cell body membrane; and perinuclear region of cytoplasm. Used to study Parkinsonism; glomerulonephritis; hepatopulmonary syndrome; and status epilepticus. Biomarker of several diseases, including anti-basement membrane glomerulonephritis; artery disease (multiple); borna disease; portal hypertension; and sciatic neuropathy. Human ortholog(s) of this gene implicated in several diseases, including human immunodeficiency virus infectious disease; obesity; pulmonary hypertension; retinal disease (multiple); and systemic scleroderma. Orthologous to human CX3CR1 (C-X3-C motif chemokine receptor 1). [provided by Alliance of Genome Resources, Jul 2025]
Rat Cx3cr1 Related Products
| Product Type | Key Applications | Cat. No. | Product |
|---|---|---|---|
| Lentiviral Vector & Virus | Stable overexpression | LC617158 | View Product |
| AAV Vector & Virus | Long-term expression | VC617158 | View Product |
| Adenovirus | Transient expression | A617158 | View Product |
| CRISPR KO Tools | Gene knockout (Lentiviral) | LG617158 | View Product |
| Gene knockout (non-viral) | PG617158 | View Product | |
| Gene knockout (AAV) | VG617158 | View Product | |
| CRISPR Activation | Gene activation | LA617158 | View Product |
| siRNA Tools | Gene knockdown (Lentiviral) | LS617158 | View Product |
| Gene knockdown (AAV) | VS617158 | View Product | |
| ORF Vector | Template DNA | PC617158 | View Product |
Accelerate Discovery with Research-Ready Constructs
| Why Researchers Choose abm | Workflow Benefits |
|---|---|
| Gene-Specific Constructs | Eliminate time-consuming cloning and accelerate project timelines |
| Available as Plasmid DNA or Packaged Virus | Choose delivery format that best fits your experiment |
| Validated Sequence Design | Ensure reliable, reproducible experimental performance |
| Available in Multiple Species Options | Simplify cross-species and translational research studies |
| Flexible Customization Services | Tailor constructs with different promoters, tags, markers and other modifications |
| Expert Technical Support | Get guidance from gene delivery specialists |
Product Overview & Key Features
| System | Applications | Key Features |
|---|---|---|
| CRISPR Knockout Vectors & Viruses | Targeted gene disruption & functional knockout studies | •Pre-designed validated sgRNAs •Available in All-in-One Cas9 + sgRNA or sgRNA-only formats •Available as lentivirus, AAV and non-viral •Ideal for stable genome editing |
| Lentiviral Expression Vectors & Particles | Stable gene overexpression or delivery into difficult-to-transfect cells | •Long-term expression through genomic integration •Highly efficient in dividing and non-dividing cells •Ideal for stable cell line generation |
| AAV Vectors & Packaged Virus | In vivo delivery & transient expression with low immunogenicity | •Multiple serotypes available for tissue targeting •Excellent for animal studies and sensitive primary cells •Episomal expression with strong safety profile |
| Adenovirus | High-efficiency transient expression | •Rapid, robust gene expression •Large cargo capacity •Ideal for primary cells and strong short-term expression studies |
| ORF Vector | Template for coding sequence | •Ready-to-use full-length coding sequences •Low cost and convenient alternative to gene synthesis |
| siRNA Knockdown Tools | Temporary gene silencing & pathway validation | •Robust gene knockdown •Ideal for target validation and preliminary functional screening •Available as Lentivirus, AAV or synthetic dsRNA oligos |