CXCL10 Expression Vectors, Lentivirus & CRISPR Knockout Vectors
Enhance your research with ready-to-use CXCL10-specific vectors and viral particles designed for reliable CXCL10 overexpression, knockout, and silencing across a wide range of experimental systems. abm offers a complete portfolio of validated molecular tools – including CXCL10 CRISPR knockout vectors, lentiviral particles, AAV vectors, adenovirus, ORF clones, and siRNA constructs for both in vitro and in vivo applications.
Human CXCL10 Gene Overview
| Gene Name | C-X-C motif chemokine ligand 10 |
|---|---|
| Gene Symbol | CXCL10 |
| Synonyms | C7,IFI10,INP10,IP-10,crg-2,mob-1,SCYB10,gIP-10 |
| NCBI ID | 3627 |
| Ensembl ID | ENSG00000169245 |
| Uniprot ID | P02778 |
| Gene Type | Protein coding |
Gene Summary
This antimicrobial gene encodes a chemokine of the CXC subfamily and ligand for the receptor CXCR3. Binding of this protein to CXCR3 results in pleiotropic effects, including stimulation of monocytes, natural killer and T-cell migration, and modulation of adhesion molecule expression. This gene may also be a key regulator of the 'cytokine storm' immune response to SARS-CoV-2 infection. [provided by RefSeq, Sep 2020]
Human CXCL10 Related Products
| Product Type | Key Applications | Cat. No. | Product |
|---|---|---|---|
| Lentiviral Vector & Virus | Stable overexpression | LC117166 | View Product |
| AAV Vector & Virus | Long-term expression | VC117166 | View Product |
| Adenovirus | Transient expression | A117166 | View Product |
| CRISPR KO Tools | Gene knockout (Lentiviral) | LG117166 | View Product |
| Gene knockout (non-viral) | PG117166 | View Product | |
| Gene knockout (AAV) | VG117166 | View Product | |
| CRISPR Activation | Gene activation | LA117166 | View Product |
| siRNA Tools | Gene knockdown (Lentiviral) | LS117166 | View Product |
| Gene knockdown (AAV) | VS117166 | View Product | |
| ORF Vector | Template DNA | PC117166 | View Product |
Mouse Cxcl10 Gene Overview
| Gene Name | C-X-C motif chemokine ligand 10 |
|---|---|
| Gene Symbol | Cxcl10 |
| Synonyms | C7,IP10,CRG-2,INP10,IP-10,Ifi10,mob-1,Scyb10,gIP-10 |
| NCBI ID | 15945 |
| Ensembl ID | ENSMUSG00000034855 |
| Uniprot ID | P17515 |
| Gene Type | Protein coding |
Gene Summary
Predicted to enable chemoattractant activity; chemokine receptor binding activity; and heparin binding activity. Involved in cellular response to interleukin-17. Acts upstream of or within several processes, including defense response to virus; negative regulation of myoblast differentiation; and negative regulation of myoblast fusion. Located in external side of plasma membrane and extracellular space. Is expressed in several structures, including alimentary system; axial skeleton; hemolymphoid system; lacrimal gland; and liver. Human ortholog(s) of this gene implicated in hepatitis B; middle cerebral artery infarction; and type 1 diabetes mellitus. Orthologous to human CXCL10 (C-X-C motif chemokine ligand 10). [provided by Alliance of Genome Resources, Jul 2025]
Mouse Cxcl10 Related Products
| Product Type | Key Applications | Cat. No. | Product |
|---|---|---|---|
| Lentiviral Vector & Virus | Stable overexpression | LC417166 | View Product |
| AAV Vector & Virus | Long-term expression | VC417166 | View Product |
| Adenovirus | Transient expression | A417166 | View Product |
| CRISPR KO Tools | Gene knockout (Lentiviral) | LG417166 | View Product |
| Gene knockout (non-viral) | PG417166 | View Product | |
| Gene knockout (AAV) | VG417166 | View Product | |
| CRISPR Activation | Gene activation | LA417166 | View Product |
| siRNA Tools | Gene knockdown (Lentiviral) | LS417166 | View Product |
| Gene knockdown (AAV) | VS417166 | View Product | |
| ORF Vector | Template DNA | PC417166 | View Product |
Rat Cxcl10 Gene Overview
| Gene Name | C-X-C motif chemokine ligand 10 |
|---|---|
| Gene Symbol | Cxcl10 |
| Synonyms | IP-10,Scyb10 |
| NCBI ID | 245920 |
| Ensembl ID | ENSRNOG00000022256 |
| Uniprot ID | P48973 |
| Gene Type | Protein coding |
Gene Summary
Enables chemokine activity. Involved in several processes, including response to auditory stimulus; response to gamma radiation; and response to vitamin D. Located in extracellular space. Used to study adult respiratory distress syndrome; myocarditis; proteinuria; renovascular hypertension; and type 1 diabetes mellitus. Biomarker of brain infarction; brain ischemia; encephalitis; interstitial cystitis; and uveitis. Human ortholog(s) of this gene implicated in hepatitis B and middle cerebral artery infarction. Orthologous to human CXCL10 (C-X-C motif chemokine ligand 10). [provided by Alliance of Genome Resources, Jul 2025]
Rat Cxcl10 Related Products
| Product Type | Key Applications | Cat. No. | Product |
|---|---|---|---|
| Lentiviral Vector & Virus | Stable overexpression | LC617166 | View Product |
| AAV Vector & Virus | Long-term expression | VC617166 | View Product |
| Adenovirus | Transient expression | A617166 | View Product |
| CRISPR KO Tools | Gene knockout (Lentiviral) | LG617166 | View Product |
| Gene knockout (non-viral) | PG617166 | View Product | |
| Gene knockout (AAV) | VG617166 | View Product | |
| CRISPR Activation | Gene activation | LA617166 | View Product |
| siRNA Tools | Gene knockdown (Lentiviral) | LS617166 | View Product |
| Gene knockdown (AAV) | VS617166 | View Product | |
| ORF Vector | Template DNA | PC617166 | View Product |
Accelerate Discovery with Research-Ready Constructs
| Why Researchers Choose abm | Workflow Benefits |
|---|---|
| Gene-Specific Constructs | Eliminate time-consuming cloning and accelerate project timelines |
| Available as Plasmid DNA or Packaged Virus | Choose delivery format that best fits your experiment |
| Validated Sequence Design | Ensure reliable, reproducible experimental performance |
| Available in Multiple Species Options | Simplify cross-species and translational research studies |
| Flexible Customization Services | Tailor constructs with different promoters, tags, markers and other modifications |
| Expert Technical Support | Get guidance from gene delivery specialists |
Product Overview & Key Features
| System | Applications | Key Features |
|---|---|---|
| CRISPR Knockout Vectors & Viruses | Targeted gene disruption & functional knockout studies | •Pre-designed validated sgRNAs •Available in All-in-One Cas9 + sgRNA or sgRNA-only formats •Available as lentivirus, AAV and non-viral •Ideal for stable genome editing |
| Lentiviral Expression Vectors & Particles | Stable gene overexpression or delivery into difficult-to-transfect cells | •Long-term expression through genomic integration •Highly efficient in dividing and non-dividing cells •Ideal for stable cell line generation |
| AAV Vectors & Packaged Virus | In vivo delivery & transient expression with low immunogenicity | •Multiple serotypes available for tissue targeting •Excellent for animal studies and sensitive primary cells •Episomal expression with strong safety profile |
| Adenovirus | High-efficiency transient expression | •Rapid, robust gene expression •Large cargo capacity •Ideal for primary cells and strong short-term expression studies |
| ORF Vector | Template for coding sequence | •Ready-to-use full-length coding sequences •Low cost and convenient alternative to gene synthesis |
| siRNA Knockdown Tools | Temporary gene silencing & pathway validation | •Robust gene knockdown •Ideal for target validation and preliminary functional screening •Available as Lentivirus, AAV or synthetic dsRNA oligos |