CXCL12 Expression Vectors, Lentivirus & CRISPR Knockout Vectors
Enhance your research with ready-to-use CXCL12-specific vectors and viral particles designed for reliable CXCL12 overexpression, knockout, and silencing across a wide range of experimental systems. abm offers a complete portfolio of validated molecular tools – including CXCL12 CRISPR knockout vectors, lentiviral particles, AAV vectors, adenovirus, ORF clones, and siRNA constructs for both in vitro and in vivo applications.
Human CXCL12 Gene Overview
| Gene Name | C-X-C motif chemokine ligand 12 |
|---|---|
| Gene Symbol | CXCL12 |
| Synonyms | IRH,PBSF,SDF1,TLSF,TPAR1,SCYB12 |
| NCBI ID | 6387 |
| Ensembl ID | ENSG00000107562 |
| Uniprot ID | P48061 |
| Gene Type | Protein coding |
Gene Summary
This antimicrobial gene encodes a stromal cell-derived alpha chemokine member of the intercrine family. The encoded protein functions as the ligand for the G-protein coupled receptor, chemokine (C-X-C motif) receptor 4, and plays a role in many diverse cellular functions, including embryogenesis, immune surveillance, inflammation response, tissue homeostasis, and tumor growth and metastasis. Mutations in this gene are associated with resistance to human immunodeficiency virus type 1 infections. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2014]
Human CXCL12 Related Products
| Product Type | Key Applications | Cat. No. | Product |
|---|---|---|---|
| Lentiviral Vector & Virus | Stable overexpression | LC117168 | View Product |
| AAV Vector & Virus | Long-term expression | VC117168 | View Product |
| Adenovirus | Transient expression | A117168 | View Product |
| CRISPR KO Tools | Gene knockout (Lentiviral) | LG117168 | View Product |
| Gene knockout (Lentiviral) | LG167291 | View Product | |
| Gene knockout (non-viral) | PG117168 | View Product | |
| Gene knockout (non-viral) | PG167291 | View Product | |
| Gene knockout (AAV) | VG117168 | View Product | |
| Gene knockout (AAV) | VG167291 | View Product | |
| CRISPR Activation | Gene activation | LA117168 | View Product |
| Gene activation | LA167291 | View Product | |
| siRNA Tools | Gene knockdown (Lentiviral) | LS117168 | View Product |
| Gene knockdown (AAV) | VS117168 | View Product | |
| Gene knockdown (AAV) | VS167291 | View Product | |
| ORF Vector | Template DNA | PC117168 | View Product |
Mouse Cxcl12 Gene Overview
| Gene Name | C-X-C motif chemokine ligand 12 |
|---|---|
| Gene Symbol | Cxcl12 |
| Synonyms | Pbsf,Sdf1,Tlsf,Tpar1,Scyb12 |
| NCBI ID | 20315 |
| Ensembl ID | ENSMUSG00000061353 |
| Uniprot ID | P40224 |
| Gene Type | Protein coding |
Gene Summary
This gene encodes a member of the alpha chemokine protein family. The encoded protein is secreted and functions as the ligand for the G-protein coupled receptor, chemokine (C-X-C motif) receptor 4. The encoded protein plays a role in many diverse cellular functions, including embryogenesis, immune surveillance, inflammation response, tissue homeostasis, and tumor growth and metastasis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2013]
Mouse Cxcl12 Related Products
| Product Type | Key Applications | Cat. No. | Product |
|---|---|---|---|
| Lentiviral Vector & Virus | Stable overexpression | LC417168 | View Product |
| Stable overexpression | LC517168 | View Product | |
| AAV Vector & Virus | Long-term expression | VC417168 | View Product |
| Long-term expression | VC517168 | View Product | |
| Adenovirus | Transient expression | A417168 | View Product |
| Transient expression | A517168 | View Product | |
| CRISPR KO Tools | Gene knockout (Lentiviral) | LG417168 | View Product |
| Gene knockout (non-viral) | PG417168 | View Product | |
| Gene knockout (AAV) | VG417168 | View Product | |
| CRISPR Activation | Gene activation | LA417168 | View Product |
| siRNA Tools | Gene knockdown (Lentiviral) | LS417168 | View Product |
| Gene knockdown (AAV) | VS417168 | View Product | |
| ORF Vector | Template DNA | PC417168 | View Product |
| Template DNA | PC517168 | View Product |
Rat Cxcl12 Gene Overview
| Gene Name | C-X-C motif chemokine ligand 12 |
|---|---|
| Gene Symbol | Cxcl12 |
| Synonyms | Sdf1 |
| NCBI ID | 24772 |
| Ensembl ID | ENSRNOG00000013589 |
| Uniprot ID | |
| Gene Type | Protein coding |
Gene Summary
Predicted to enable CXCR chemokine receptor binding activity; chemokine activity; and integrin binding activity. Involved in several processes, including detection of stimulus involved in sensory perception of pain; nervous system development; and positive regulation of cell differentiation. Located in extracellular space. Used to study myocardial infarction. Biomarker of anti-basement membrane glomerulonephritis; brain ischemia (multiple); myocardial infarction; status epilepticus; and traumatic brain injury. Human ortholog(s) of this gene implicated in breast carcinoma; diabetic angiopathy; human immunodeficiency virus infectious disease; and type 1 diabetes mellitus. Orthologous to human CXCL12 (C-X-C motif chemokine ligand 12). [provided by Alliance of Genome Resources, Jul 2025]
Rat Cxcl12 Related Products
| Product Type | Key Applications | Cat. No. | Product |
|---|---|---|---|
| Lentiviral Vector & Virus | Stable overexpression | LC617168 | View Product |
| Stable overexpression | LC717168 | View Product | |
| AAV Vector & Virus | Long-term expression | VC617168 | View Product |
| Long-term expression | VC717168 | View Product | |
| Adenovirus | Transient expression | A617168 | View Product |
| Transient expression | A717168 | View Product | |
| CRISPR KO Tools | Gene knockout (Lentiviral) | LG617168 | View Product |
| Gene knockout (non-viral) | PG617168 | View Product | |
| Gene knockout (AAV) | VG617168 | View Product | |
| CRISPR Activation | Gene activation | LA617168 | View Product |
| siRNA Tools | Gene knockdown (Lentiviral) | LS617168 | View Product |
| Gene knockdown (AAV) | VS617168 | View Product | |
| ORF Vector | Template DNA | PC617168 | View Product |
| Template DNA | PC717168 | View Product |
Accelerate Discovery with Research-Ready Constructs
| Why Researchers Choose abm | Workflow Benefits |
|---|---|
| Gene-Specific Constructs | Eliminate time-consuming cloning and accelerate project timelines |
| Available as Plasmid DNA or Packaged Virus | Choose delivery format that best fits your experiment |
| Validated Sequence Design | Ensure reliable, reproducible experimental performance |
| Available in Multiple Species Options | Simplify cross-species and translational research studies |
| Flexible Customization Services | Tailor constructs with different promoters, tags, markers and other modifications |
| Expert Technical Support | Get guidance from gene delivery specialists |
Product Overview & Key Features
| System | Applications | Key Features |
|---|---|---|
| CRISPR Knockout Vectors & Viruses | Targeted gene disruption & functional knockout studies | •Pre-designed validated sgRNAs •Available in All-in-One Cas9 + sgRNA or sgRNA-only formats •Available as lentivirus, AAV and non-viral •Ideal for stable genome editing |
| Lentiviral Expression Vectors & Particles | Stable gene overexpression or delivery into difficult-to-transfect cells | •Long-term expression through genomic integration •Highly efficient in dividing and non-dividing cells •Ideal for stable cell line generation |
| AAV Vectors & Packaged Virus | In vivo delivery & transient expression with low immunogenicity | •Multiple serotypes available for tissue targeting •Excellent for animal studies and sensitive primary cells •Episomal expression with strong safety profile |
| Adenovirus | High-efficiency transient expression | •Rapid, robust gene expression •Large cargo capacity •Ideal for primary cells and strong short-term expression studies |
| ORF Vector | Template for coding sequence | •Ready-to-use full-length coding sequences •Low cost and convenient alternative to gene synthesis |
| siRNA Knockdown Tools | Temporary gene silencing & pathway validation | •Robust gene knockdown •Ideal for target validation and preliminary functional screening •Available as Lentivirus, AAV or synthetic dsRNA oligos |