EGR1 Expression Vectors, Lentivirus & CRISPR Knockout Vectors
Enhance your research with ready-to-use EGR1-specific vectors and viral particles designed for reliable EGR1 overexpression, knockout, and silencing across a wide range of experimental systems. abm offers a complete portfolio of validated molecular tools – including EGR1 CRISPR knockout vectors, lentiviral particles, AAV vectors, adenovirus, ORF clones, and siRNA constructs for both in vitro and in vivo applications.
Human EGR1 Gene Overview
| Gene Name | early growth response 1 |
|---|---|
| Gene Symbol | EGR1 |
| Synonyms | TIS8,AT225,G0S30,NGFI-A,ZIF268,ZNF225,KROX-24,ZIF-268 |
| NCBI ID | 1958 |
| Ensembl ID | ENSG00000120738 |
| Uniprot ID | P18146 |
| Gene Type | Protein coding |
Gene Summary
The protein encoded by this gene belongs to the EGR family of C2H2-type zinc-finger proteins. It is a nuclear protein and functions as a transcriptional regulator. The products of target genes it activates are required for differentitation and mitogenesis. Studies suggest this is a cancer suppressor gene. [provided by RefSeq, Dec 2014]
Human EGR1 Related Products
| Product Type | Key Applications | Cat. No. | Product |
|---|---|---|---|
| Lentiviral Vector & Virus | Stable overexpression | LC119045 | View Product |
| AAV Vector & Virus | Long-term expression | VC119045 | View Product |
| Adenovirus | Transient expression | A119045 | View Product |
| CRISPR KO Tools | Gene knockout (Lentiviral) | LG119045 | View Product |
| Gene knockout (non-viral) | PG119045 | View Product | |
| Gene knockout (AAV) | VG119045 | View Product | |
| CRISPR Activation | Gene activation | LA119045 | View Product |
| siRNA Tools | Gene knockdown (Lentiviral) | LS119045 | View Product |
| Gene knockdown (AAV) | VS119045 | View Product | |
| ORF Vector | Template DNA | PC119045 | View Product |
Mouse Egr1 Gene Overview
| Gene Name | early growth response 1 |
|---|---|
| Gene Symbol | Egr1 |
| Synonyms | egr,TIS8,Zenk,Egr-1,NGFIA,Zfp-6,ETR103,Krox-1,Krox24,NGF1-A,NGFI-A,Zif268,Krox-24,A530045N19Rik |
| NCBI ID | 13653 |
| Ensembl ID | ENSMUSG00000038418 |
| Uniprot ID | P08046 |
| Gene Type | Protein coding |
Gene Summary
Enables DNA-binding transcription activator activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and enzyme binding activity. Involved in several processes, including cellular response to gamma radiation; circadian temperature homeostasis; and regulation of biosynthetic process. Acts upstream of or within several processes, including BMP signaling pathway; cellular response to hypoxia; and skeletal muscle cell differentiation. Located in nucleus. Is expressed in several structures, including brain; embryo mesenchyme; eye; genitourinary system; and jaw. Used to study myelodysplastic syndrome. Human ortholog(s) of this gene implicated in asthma. Orthologous to human EGR1 (early growth response 1). [provided by Alliance of Genome Resources, Apr 2025]
Mouse Egr1 Related Products
| Product Type | Key Applications | Cat. No. | Product |
|---|---|---|---|
| Lentiviral Vector & Virus | Stable overexpression | LC419045 | View Product |
| AAV Vector & Virus | Long-term expression | VC419045 | View Product |
| Adenovirus | Transient expression | A419045 | View Product |
| CRISPR KO Tools | Gene knockout (Lentiviral) | LG419045 | View Product |
| Gene knockout (non-viral) | PG419045 | View Product | |
| Gene knockout (AAV) | VG419045 | View Product | |
| CRISPR Activation | Gene activation | LA419045 | View Product |
| siRNA Tools | Gene knockdown (Lentiviral) | LS419045 | View Product |
| Gene knockdown (AAV) | VS419045 | View Product | |
| ORF Vector | Template DNA | PC419045 | View Product |
Rat Egr1 Gene Overview
| Gene Name | early growth response 1 |
|---|---|
| Gene Symbol | Egr1 |
| Synonyms | Ngf1,Ngfi,NGFI-A,Krox-24,zif-268 |
| NCBI ID | 24330 |
| Ensembl ID | ENSRNOG00000019422 |
| Uniprot ID | P08154 |
| Gene Type | Protein coding |
Gene Summary
Enables DNA-binding transcription activator activity, RNA polymerase II-specific; RNA polymerase II transcription regulatory region sequence-specific DNA binding activity; and promoter-specific chromatin binding activity. Involved in several processes, including positive regulation of cell population proliferation; regulation of synaptic plasticity; and response to isoquinoline alkaloid. Located in cytoplasm and nucleus. Biomarker of several diseases, including cocaine dependence; lung disease (multiple); middle cerebral artery infarction; pancreatitis; and pulmonary hypertension. Human ortholog(s) of this gene implicated in asthma. Orthologous to human EGR1 (early growth response 1). [provided by Alliance of Genome Resources, Jul 2025]
Rat Egr1 Related Products
| Product Type | Key Applications | Cat. No. | Product |
|---|---|---|---|
| Lentiviral Vector & Virus | Stable overexpression | LC619045 | View Product |
| AAV Vector & Virus | Long-term expression | VC619045 | View Product |
| siRNA Tools | Gene knockdown (AAV) | VS619045 | View Product |
| ORF Vector | Template DNA | PC619045 | View Product |
Accelerate Discovery with Research-Ready Constructs
| Why Researchers Choose abm | Workflow Benefits |
|---|---|
| Gene-Specific Constructs | Eliminate time-consuming cloning and accelerate project timelines |
| Available as Plasmid DNA or Packaged Virus | Choose delivery format that best fits your experiment |
| Validated Sequence Design | Ensure reliable, reproducible experimental performance |
| Available in Multiple Species Options | Simplify cross-species and translational research studies |
| Flexible Customization Services | Tailor constructs with different promoters, tags, markers and other modifications |
| Expert Technical Support | Get guidance from gene delivery specialists |
Product Overview & Key Features
| System | Applications | Key Features |
|---|---|---|
| CRISPR Knockout Vectors & Viruses | Targeted gene disruption & functional knockout studies | •Pre-designed validated sgRNAs •Available in All-in-One Cas9 + sgRNA or sgRNA-only formats •Available as lentivirus, AAV and non-viral •Ideal for stable genome editing |
| Lentiviral Expression Vectors & Particles | Stable gene overexpression or delivery into difficult-to-transfect cells | •Long-term expression through genomic integration •Highly efficient in dividing and non-dividing cells •Ideal for stable cell line generation |
| AAV Vectors & Packaged Virus | In vivo delivery & transient expression with low immunogenicity | •Multiple serotypes available for tissue targeting •Excellent for animal studies and sensitive primary cells •Episomal expression with strong safety profile |
| Adenovirus | High-efficiency transient expression | •Rapid, robust gene expression •Large cargo capacity •Ideal for primary cells and strong short-term expression studies |
| ORF Vector | Template for coding sequence | •Ready-to-use full-length coding sequences •Low cost and convenient alternative to gene synthesis |
| siRNA Knockdown Tools | Temporary gene silencing & pathway validation | •Robust gene knockdown •Ideal for target validation and preliminary functional screening •Available as Lentivirus, AAV or synthetic dsRNA oligos |