EPCAM Expression Vectors, Lentivirus & CRISPR Knockout Vectors
Enhance your research with ready-to-use EPCAM-specific vectors and viral particles designed for reliable EPCAM overexpression, knockout, and silencing across a wide range of experimental systems. abm offers a complete portfolio of validated molecular tools – including EPCAM CRISPR knockout vectors, lentiviral particles, AAV vectors, adenovirus, ORF clones, and siRNA constructs for both in vitro and in vivo applications.
Human EPCAM Gene Overview
| Gene Name | epithelial cell adhesion molecule |
|---|---|
| Gene Symbol | EPCAM |
| Synonyms | ESA,KSA,M4S1,MK-1,DIAR5,EGP-2,EGP40,KS1/4,MIC18,TROP1,BerEp4,EGP314,HNPCC8,LYNCH8,MOC-31,Ber-Ep4,TACSTD1 |
| NCBI ID | 4072 |
| Ensembl ID | ENSG00000119888 |
| Uniprot ID | P16422 |
| Gene Type | Protein coding |
Gene Summary
This gene encodes a carcinoma-associated antigen and is a member of a family that includes at least two type I membrane proteins. This antigen is expressed on most normal epithelial cells and gastrointestinal carcinomas and functions as a homotypic calcium-independent cell adhesion molecule. The antigen is being used as a target for immunotherapy treatment of human carcinomas. Mutations in this gene result in congenital tufting enteropathy. [provided by RefSeq, Dec 2008]
Human EPCAM Related Products
| Product Type | Key Applications | Cat. No. | Product |
|---|---|---|---|
| Lentiviral Vector & Virus | Stable overexpression | LC119349 | View Product |
| AAV Vector & Virus | Long-term expression | VC119349 | View Product |
| Adenovirus | Transient expression | A119349 | View Product |
| CRISPR KO Tools | Gene knockout (Lentiviral) | LG119349 | View Product |
| Gene knockout (non-viral) | PG119349 | View Product | |
| Gene knockout (AAV) | VG119349 | View Product | |
| CRISPR Activation | Gene activation | LA119349 | View Product |
| siRNA Tools | Gene knockdown (Lentiviral) | LS219349 | View Product |
| Gene knockdown (AAV) | VS119349 | View Product | |
| Gene knockdown (AAV) | VS219349 | View Product | |
| ORF Vector | Template DNA | PC119349 | View Product |
Mouse Epcam Gene Overview
| Gene Name | epithelial cell adhesion molecule |
|---|---|
| Gene Symbol | Epcam |
| Synonyms | EGP,Ly74,gp40,CD326,EGP-2,TROP1,Egp314,Ep-CAM,EpCAM1,Tacsd1,GA733-2,Tacstd1 |
| NCBI ID | 17075 |
| Ensembl ID | ENSMUSG00000045394 |
| Uniprot ID | Q99JW5 |
| Gene Type | Protein coding |
Gene Summary
Predicted to enable cadherin binding activity involved in cell-cell adhesion. Involved in ureteric bud development. Located in cell surface. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; respiratory system; and sensory organ. Used to study congenital diarrhea 5 with tufting enteropathy. Human ortholog(s) of this gene implicated in congenital diarrhea 5 with tufting enteropathy and hereditary nonpolyposis colorectal cancer type 8. Orthologous to human EPCAM (epithelial cell adhesion molecule). [provided by Alliance of Genome Resources, Jul 2025]
Mouse Epcam Related Products
| Product Type | Key Applications | Cat. No. | Product |
|---|---|---|---|
| Lentiviral Vector & Virus | Stable overexpression | LC419349 | View Product |
| AAV Vector & Virus | Long-term expression | VC419349 | View Product |
| Adenovirus | Transient expression | A419349 | View Product |
| CRISPR KO Tools | Gene knockout (Lentiviral) | LG419349 | View Product |
| Gene knockout (non-viral) | PG419349 | View Product | |
| Gene knockout (AAV) | VG419349 | View Product | |
| CRISPR Activation | Gene activation | LA419349 | View Product |
| siRNA Tools | Gene knockdown (Lentiviral) | LS419349 | View Product |
| Gene knockdown (AAV) | VS419349 | View Product | |
| ORF Vector | Template DNA | PC419349 | View Product |
Rat Epcam Gene Overview
| Gene Name | epithelial cell adhesion molecule |
|---|---|
| Gene Symbol | Epcam |
| Synonyms | Egp314,Tacstd1 |
| NCBI ID | 171577 |
| Ensembl ID | ENSRNOG00000015667 |
| Uniprot ID | O55159 |
| Gene Type | Protein coding |
Gene Summary
Enables cadherin binding activity involved in cell-cell adhesion. Involved in cell-cell adhesion via plasma-membrane adhesion molecules; negative regulation of apoptotic process; and positive regulation of cell motility. Located in bicellular tight junction; cell surface; and lateral plasma membrane. Biomarker of middle cerebral artery infarction. Human ortholog(s) of this gene implicated in congenital diarrhea 5 with tufting enteropathy and hereditary nonpolyposis colorectal cancer type 8. Orthologous to human EPCAM (epithelial cell adhesion molecule). [provided by Alliance of Genome Resources, Jul 2025]
Rat Epcam Related Products
| Product Type | Key Applications | Cat. No. | Product |
|---|---|---|---|
| Lentiviral Vector & Virus | Stable overexpression | LC619349 | View Product |
| AAV Vector & Virus | Long-term expression | VC619349 | View Product |
| Adenovirus | Transient expression | A619349 | View Product |
| CRISPR KO Tools | Gene knockout (Lentiviral) | LG619349 | View Product |
| Gene knockout (non-viral) | PG619349 | View Product | |
| Gene knockout (AAV) | VG619349 | View Product | |
| CRISPR Activation | Gene activation | LA619349 | View Product |
| siRNA Tools | Gene knockdown (Lentiviral) | LS619349 | View Product |
| Gene knockdown (AAV) | VS619349 | View Product | |
| ORF Vector | Template DNA | PC619349 | View Product |
Accelerate Discovery with Research-Ready Constructs
| Why Researchers Choose abm | Workflow Benefits |
|---|---|
| Gene-Specific Constructs | Eliminate time-consuming cloning and accelerate project timelines |
| Available as Plasmid DNA or Packaged Virus | Choose delivery format that best fits your experiment |
| Validated Sequence Design | Ensure reliable, reproducible experimental performance |
| Available in Multiple Species Options | Simplify cross-species and translational research studies |
| Flexible Customization Services | Tailor constructs with different promoters, tags, markers and other modifications |
| Expert Technical Support | Get guidance from gene delivery specialists |
Product Overview & Key Features
| System | Applications | Key Features |
|---|---|---|
| CRISPR Knockout Vectors & Viruses | Targeted gene disruption & functional knockout studies | •Pre-designed validated sgRNAs •Available in All-in-One Cas9 + sgRNA or sgRNA-only formats •Available as lentivirus, AAV and non-viral •Ideal for stable genome editing |
| Lentiviral Expression Vectors & Particles | Stable gene overexpression or delivery into difficult-to-transfect cells | •Long-term expression through genomic integration •Highly efficient in dividing and non-dividing cells •Ideal for stable cell line generation |
| AAV Vectors & Packaged Virus | In vivo delivery & transient expression with low immunogenicity | •Multiple serotypes available for tissue targeting •Excellent for animal studies and sensitive primary cells •Episomal expression with strong safety profile |
| Adenovirus | High-efficiency transient expression | •Rapid, robust gene expression •Large cargo capacity •Ideal for primary cells and strong short-term expression studies |
| ORF Vector | Template for coding sequence | •Ready-to-use full-length coding sequences •Low cost and convenient alternative to gene synthesis |
| siRNA Knockdown Tools | Temporary gene silencing & pathway validation | •Robust gene knockdown •Ideal for target validation and preliminary functional screening •Available as Lentivirus, AAV or synthetic dsRNA oligos |