FOXA2 Expression Vectors, Lentivirus & CRISPR Knockout Vectors
Enhance your research with ready-to-use FOXA2-specific vectors and viral particles designed for reliable FOXA2 overexpression, knockout, and silencing across a wide range of experimental systems. abm offers a complete portfolio of validated molecular tools – including FOXA2 CRISPR knockout vectors, lentiviral particles, AAV vectors, adenovirus, ORF clones, and siRNA constructs for both in vitro and in vivo applications.
Human FOXA2 Gene Overview
| Gene Name | forkhead box A2 |
|---|---|
| Gene Symbol | FOXA2 |
| Synonyms | HNF3B,TCF3B,HNF-3-beta |
| NCBI ID | 3170 |
| Ensembl ID | ENSG00000125798 |
| Uniprot ID | Q9Y261 |
| Gene Type | Protein coding |
Gene Summary
This gene encodes a member of the forkhead class of DNA-binding proteins. These hepatocyte nuclear factors are transcriptional activators for liver-specific genes such as albumin and transthyretin, and they also interact with chromatin. Similar family members in mice have roles in the regulation of metabolism and in the differentiation of the pancreas and liver. This gene has been linked to sporadic cases of maturity-onset diabetes of the young. Transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Oct 2008]
Human FOXA2 Related Products
| Product Type | Key Applications | Cat. No. | Product |
|---|---|---|---|
| Lentiviral Vector & Virus | Stable overexpression | LC120750 | View Product |
| AAV Vector & Virus | Long-term expression | VC120750 | View Product |
| Adenovirus | Transient expression | A120750 | View Product |
| CRISPR KO Tools | Gene knockout (Lentiviral) | LG120750 | View Product |
| Gene knockout (non-viral) | PG120750 | View Product | |
| Gene knockout (AAV) | VG120750 | View Product | |
| CRISPR Activation | Gene activation | LA120750 | View Product |
| siRNA Tools | Gene knockdown (Lentiviral) | LS120750 | View Product |
| Gene knockdown (AAV) | VS120750 | View Product | |
| ORF Vector | Template DNA | PC120750 | View Product |
Mouse Foxa2 Gene Overview
| Gene Name | forkhead box A2 |
|---|---|
| Gene Symbol | Foxa2 |
| Synonyms | Hnf3b,Tcf3b,Hnf-3b,Tcf-3b,HNF3beta,HNF3-beta |
| NCBI ID | 15376 |
| Ensembl ID | ENSMUSG00000037025 |
| Uniprot ID | P35583 |
| Gene Type | Protein coding |
Gene Summary
Enables DNA-binding transcription factor activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and chromatin binding activity. Involved in several processes, including positive regulation of gastrulation; primitive streak formation; and regulation of DNA-templated transcription. Acts upstream of or within several processes, including chordate embryonic development; lung development; and regulation of neuron differentiation. Located in nucleus. Part of transcription regulator complex. Is expressed in several structures, including central nervous system; endoderm; genitourinary system; gut; and respiratory system. Human ortholog(s) of this gene implicated in type 2 diabetes mellitus. Orthologous to human FOXA2 (forkhead box A2). [provided by Alliance of Genome Resources, Jul 2025]
Mouse Foxa2 Related Products
| Product Type | Key Applications | Cat. No. | Product |
|---|---|---|---|
| Lentiviral Vector & Virus | Stable overexpression | LC420750 | View Product |
| AAV Vector & Virus | Long-term expression | VC420750 | View Product |
| Adenovirus | Transient expression | A420750 | View Product |
| CRISPR KO Tools | Gene knockout (Lentiviral) | LG420750 | View Product |
| Gene knockout (non-viral) | PG420750 | View Product | |
| Gene knockout (AAV) | VG420750 | View Product | |
| CRISPR Activation | Gene activation | LA420750 | View Product |
| siRNA Tools | Gene knockdown (Lentiviral) | LS420750 | View Product |
| Gene knockdown (AAV) | VS420750 | View Product | |
| ORF Vector | Template DNA | PC420750 | View Product |
Rat Foxa2 Gene Overview
| Gene Name | forkhead box A2 |
|---|---|
| Gene Symbol | Foxa2 |
| Synonyms | Hnf3b |
| NCBI ID | 25099 |
| Ensembl ID | ENSRNOG00000013133 |
| Uniprot ID | P32182 |
| Gene Type | Protein coding |
Gene Summary
Enables several functions, including DNA-binding transcription activator activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and SMAD binding activity. Involved in positive regulation of transcription by RNA polymerase II and response to insulin. Located in nucleus. Human ortholog(s) of this gene implicated in type 2 diabetes mellitus. Orthologous to human FOXA2 (forkhead box A2). [provided by Alliance of Genome Resources, Apr 2025]
Rat Foxa2 Related Products
| Product Type | Key Applications | Cat. No. | Product |
|---|---|---|---|
| Lentiviral Vector & Virus | Stable overexpression | LC620750 | View Product |
| AAV Vector & Virus | Long-term expression | VC620750 | View Product |
| Adenovirus | Transient expression | A620750 | View Product |
| CRISPR KO Tools | Gene knockout (Lentiviral) | LG620750 | View Product |
| Gene knockout (non-viral) | PG620750 | View Product | |
| Gene knockout (AAV) | VG620750 | View Product | |
| CRISPR Activation | Gene activation | LA620750 | View Product |
| siRNA Tools | Gene knockdown (Lentiviral) | LS620750 | View Product |
| Gene knockdown (AAV) | VS620750 | View Product | |
| ORF Vector | Template DNA | PC620750 | View Product |
Accelerate Discovery with Research-Ready Constructs
| Why Researchers Choose abm | Workflow Benefits |
|---|---|
| Gene-Specific Constructs | Eliminate time-consuming cloning and accelerate project timelines |
| Available as Plasmid DNA or Packaged Virus | Choose delivery format that best fits your experiment |
| Validated Sequence Design | Ensure reliable, reproducible experimental performance |
| Available in Multiple Species Options | Simplify cross-species and translational research studies |
| Flexible Customization Services | Tailor constructs with different promoters, tags, markers and other modifications |
| Expert Technical Support | Get guidance from gene delivery specialists |
Product Overview & Key Features
| System | Applications | Key Features |
|---|---|---|
| CRISPR Knockout Vectors & Viruses | Targeted gene disruption & functional knockout studies | •Pre-designed validated sgRNAs •Available in All-in-One Cas9 + sgRNA or sgRNA-only formats •Available as lentivirus, AAV and non-viral •Ideal for stable genome editing |
| Lentiviral Expression Vectors & Particles | Stable gene overexpression or delivery into difficult-to-transfect cells | •Long-term expression through genomic integration •Highly efficient in dividing and non-dividing cells •Ideal for stable cell line generation |
| AAV Vectors & Packaged Virus | In vivo delivery & transient expression with low immunogenicity | •Multiple serotypes available for tissue targeting •Excellent for animal studies and sensitive primary cells •Episomal expression with strong safety profile |
| Adenovirus | High-efficiency transient expression | •Rapid, robust gene expression •Large cargo capacity •Ideal for primary cells and strong short-term expression studies |
| ORF Vector | Template for coding sequence | •Ready-to-use full-length coding sequences •Low cost and convenient alternative to gene synthesis |
| siRNA Knockdown Tools | Temporary gene silencing & pathway validation | •Robust gene knockdown •Ideal for target validation and preliminary functional screening •Available as Lentivirus, AAV or synthetic dsRNA oligos |