FOXP3 Expression Vectors, Lentivirus & CRISPR Knockout Vectors
Enhance your research with ready-to-use FOXP3-specific vectors and viral particles designed for reliable FOXP3 overexpression, knockout, and silencing across a wide range of experimental systems. abm offers a complete portfolio of validated molecular tools – including FOXP3 CRISPR knockout vectors, lentiviral particles, AAV vectors, adenovirus, ORF clones, and siRNA constructs for both in vitro and in vivo applications.
Human FOXP3 Gene Overview
| Gene Name | forkhead box P3 |
|---|---|
| Gene Symbol | FOXP3 |
| Synonyms | JM2,AIID,IPEX,PIDX,XPID,DIETER |
| NCBI ID | 50943 |
| Ensembl ID | ENSG00000049768 |
| Uniprot ID | Q9BZS1 |
| Gene Type | Protein coding |
Gene Summary
The protein encoded by this gene is a member of the forkhead/winged-helix family of transcriptional regulators. Defects in this gene are the cause of immunodeficiency polyendocrinopathy, enteropathy, X-linked syndrome (IPEX), also known as X-linked autoimmunity-immunodeficiency syndrome. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
Human FOXP3 Related Products
| Product Type | Key Applications | Cat. No. | Product |
|---|---|---|---|
| Lentiviral Vector & Virus | Stable overexpression | LC120798 | View Product |
| AAV Vector & Virus | Long-term expression | VC120798 | View Product |
| Adenovirus | Transient expression | A120798 | View Product |
| CRISPR KO Tools | Gene knockout (Lentiviral) | LG120798 | View Product |
| Gene knockout (non-viral) | PG120798 | View Product | |
| Gene knockout (AAV) | VG120798 | View Product | |
| CRISPR Activation | Gene activation | LA120798 | View Product |
| siRNA Tools | Gene knockdown (Lentiviral) | LS120798 | View Product |
| Gene knockdown (AAV) | VS120798 | View Product | |
| ORF Vector | Template DNA | PC120798 | View Product |
Mouse Foxp3 Gene Overview
| Gene Name | forkhead box P3 |
|---|---|
| Gene Symbol | Foxp3 |
| Synonyms | sf,JM2,scurfin |
| NCBI ID | 20371 |
| Ensembl ID | ENSMUSG00000039521 |
| Uniprot ID | Q99JB6 |
| Gene Type | Protein coding |
Gene Summary
The protein encoded by this gene is a member of the forkhead/winged-helix family of transcriptional regulators. Defects in this gene result in the scurfy phenotype (sf). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2015]
Mouse Foxp3 Related Products
| Product Type | Key Applications | Cat. No. | Product |
|---|---|---|---|
| Lentiviral Vector & Virus | Stable overexpression | LC420798 | View Product |
| Stable overexpression | LC520798 | View Product | |
| AAV Vector & Virus | Long-term expression | VC420798 | View Product |
| Long-term expression | VC520798 | View Product | |
| Adenovirus | Transient expression | A420798 | View Product |
| Transient expression | A520798 | View Product | |
| CRISPR KO Tools | Gene knockout (Lentiviral) | LG420798 | View Product |
| Gene knockout (non-viral) | PG420798 | View Product | |
| Gene knockout (AAV) | VG420798 | View Product | |
| CRISPR Activation | Gene activation | LA420798 | View Product |
| siRNA Tools | Gene knockdown (Lentiviral) | LS420798 | View Product |
| Gene knockdown (AAV) | VS420798 | View Product | |
| ORF Vector | Template DNA | PC420798 | View Product |
| Template DNA | PC520798 | View Product |
Rat Foxp3 Gene Overview
| Gene Name | forkhead box P3 |
|---|---|
| Gene Symbol | Foxp3 |
| Synonyms | RGD1562112 |
| NCBI ID | 317382 |
| Ensembl ID | ENSRNOG00000011702 |
| Uniprot ID | |
| Gene Type | Protein coding |
Gene Summary
Predicted to enable several functions, including DNA-binding transcription factor activity, RNA polymerase II-specific; NFAT protein binding activity; and enzyme binding activity. Involved in several processes, including establishment of endothelial blood-brain barrier; negative regulation of defense response to virus; and response to rapamycin. Predicted to be located in cytosol and nucleoplasm. Predicted to be active in nucleus. Used to study intrahepatic cholangiocarcinoma. Biomarker of Korean hemorrhagic fever; bronchial disease (multiple); graft-versus-host disease; hypertension; and hypothyroidism. Human ortholog(s) of this gene implicated in Human papillomavirus infectious disease; colorectal cancer; immune dysregulation-polyendocrinopathy-enteropathy-X-linked syndrome; pulmonary tuberculosis; and type 1 diabetes mellitus. Orthologous to human FOXP3 (forkhead box P3). [provided by Alliance of Genome Resources, Jul 2025]
Rat Foxp3 Related Products
| Product Type | Key Applications | Cat. No. | Product |
|---|---|---|---|
| Lentiviral Vector & Virus | Stable overexpression | LC620798 | View Product |
| AAV Vector & Virus | Long-term expression | VC620798 | View Product |
| Adenovirus | Transient expression | A620798 | View Product |
| CRISPR KO Tools | Gene knockout (Lentiviral) | LG620798 | View Product |
| Gene knockout (non-viral) | PG620798 | View Product | |
| Gene knockout (AAV) | VG620798 | View Product | |
| CRISPR Activation | Gene activation | LA620798 | View Product |
| siRNA Tools | Gene knockdown (Lentiviral) | LS620798 | View Product |
| Gene knockdown (AAV) | VS620798 | View Product | |
| ORF Vector | Template DNA | PC620798 | View Product |
Accelerate Discovery with Research-Ready Constructs
| Why Researchers Choose abm | Workflow Benefits |
|---|---|
| Gene-Specific Constructs | Eliminate time-consuming cloning and accelerate project timelines |
| Available as Plasmid DNA or Packaged Virus | Choose delivery format that best fits your experiment |
| Validated Sequence Design | Ensure reliable, reproducible experimental performance |
| Available in Multiple Species Options | Simplify cross-species and translational research studies |
| Flexible Customization Services | Tailor constructs with different promoters, tags, markers and other modifications |
| Expert Technical Support | Get guidance from gene delivery specialists |
Product Overview & Key Features
| System | Applications | Key Features |
|---|---|---|
| CRISPR Knockout Vectors & Viruses | Targeted gene disruption & functional knockout studies | •Pre-designed validated sgRNAs •Available in All-in-One Cas9 + sgRNA or sgRNA-only formats •Available as lentivirus, AAV and non-viral •Ideal for stable genome editing |
| Lentiviral Expression Vectors & Particles | Stable gene overexpression or delivery into difficult-to-transfect cells | •Long-term expression through genomic integration •Highly efficient in dividing and non-dividing cells •Ideal for stable cell line generation |
| AAV Vectors & Packaged Virus | In vivo delivery & transient expression with low immunogenicity | •Multiple serotypes available for tissue targeting •Excellent for animal studies and sensitive primary cells •Episomal expression with strong safety profile |
| Adenovirus | High-efficiency transient expression | •Rapid, robust gene expression •Large cargo capacity •Ideal for primary cells and strong short-term expression studies |
| ORF Vector | Template for coding sequence | •Ready-to-use full-length coding sequences •Low cost and convenient alternative to gene synthesis |
| siRNA Knockdown Tools | Temporary gene silencing & pathway validation | •Robust gene knockdown •Ideal for target validation and preliminary functional screening •Available as Lentivirus, AAV or synthetic dsRNA oligos |