GATA4 Expression Vectors, Lentivirus & CRISPR Knockout Vectors
Enhance your research with ready-to-use GATA4-specific vectors and viral particles designed for reliable GATA4 overexpression, knockout, and silencing across a wide range of experimental systems. abm offers a complete portfolio of validated molecular tools – including GATA4 CRISPR knockout vectors, lentiviral particles, AAV vectors, adenovirus, ORF clones, and siRNA constructs for both in vitro and in vivo applications.
Human GATA4 Gene Overview
| Gene Name | GATA binding protein 4 |
|---|---|
| Gene Symbol | GATA4 |
| Synonyms | TOF,ASD2,VSD1,TACHD |
| NCBI ID | 2626 |
| Ensembl ID | ENSG00000136574 |
| Uniprot ID | P43694 |
| Gene Type | Protein coding |
Gene Summary
This gene encodes a member of the GATA family of zinc-finger transcription factors. Members of this family recognize the GATA motif which is present in the promoters of many genes. This protein is thought to regulate genes involved in embryogenesis and in myocardial differentiation and function, and is necessary for normal testicular development. Mutations in this gene have been associated with cardiac septal defects. Additionally, alterations in gene expression have been associated with several cancer types. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2015]
Human GATA4 Related Products
| Product Type | Key Applications | Cat. No. | Product |
|---|---|---|---|
| Lentiviral Vector & Virus | Stable overexpression | LC121330 | View Product |
| AAV Vector & Virus | Long-term expression | VC121330 | View Product |
| Adenovirus | Transient expression | A121330 | View Product |
| CRISPR KO Tools | Gene knockout (Lentiviral) | LG121330 | View Product |
| Gene knockout (non-viral) | PG121330 | View Product | |
| Gene knockout (AAV) | VG121330 | View Product | |
| CRISPR Activation | Gene activation | LA121330 | View Product |
| siRNA Tools | Gene knockdown (Lentiviral) | LS121330 | View Product |
| Gene knockdown (AAV) | VS121330 | View Product | |
| ORF Vector | Template DNA | PC121330 | View Product |
Mouse Gata4 Gene Overview
| Gene Name | GATA binding protein 4 |
|---|---|
| Gene Symbol | Gata4 |
| Synonyms | Gata-4 |
| NCBI ID | 14463 |
| Ensembl ID | ENSMUSG00000021944 |
| Uniprot ID | Q08369 |
| Gene Type | Protein coding |
Gene Summary
Enables several functions, including DNA-binding transcription factor activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and transcription coactivator binding activity. Involved in several processes, including heart development; negative regulation of apoptotic process; and regulation of gene expression. Acts upstream of or within several processes, including embryonic morphogenesis; heart development; and male gonad development. Located in chromatin and nucleus. Is expressed in several structures, including early conceptus; embryo mesenchyme; gut; heart; and reproductive system. Used to study atrial heart septal defect 2 and congenital diaphragmatic hernia. Human ortholog(s) of this gene implicated in congenital heart disease (multiple). Orthologous to human GATA4 (GATA binding protein 4). [provided by Alliance of Genome Resources, Jul 2025]
Mouse Gata4 Related Products
| Product Type | Key Applications | Cat. No. | Product |
|---|---|---|---|
| Lentiviral Vector & Virus | Stable overexpression | LC421330 | View Product |
| AAV Vector & Virus | Long-term expression | VC421330 | View Product |
| Adenovirus | Transient expression | A521330 | View Product |
| CRISPR KO Tools | Gene knockout (Lentiviral) | LG421330 | View Product |
| Gene knockout (non-viral) | PG421330 | View Product | |
| Gene knockout (AAV) | VG421330 | View Product | |
| CRISPR Activation | Gene activation | LA421330 | View Product |
| siRNA Tools | Gene knockdown (Lentiviral) | LS421330 | View Product |
| Gene knockdown (AAV) | VS421330 | View Product | |
| ORF Vector | Template DNA | PC421330 | View Product |
Rat Gata4 Gene Overview
| Gene Name | GATA binding protein 4 |
|---|---|
| Gene Symbol | Gata4 |
| Synonyms | |
| NCBI ID | 54254 |
| Ensembl ID | ENSRNOG00000010708 |
| Uniprot ID | P46152 |
| Gene Type | Protein coding |
Gene Summary
Enables several functions, including DNA-binding transcription factor activity, RNA polymerase II-specific; NFAT protein binding activity; and cis-regulatory region sequence-specific DNA binding activity. Involved in several processes, including cell growth involved in cardiac muscle cell development; positive regulation of BMP signaling pathway; and transdifferentiation. Predicted to be located in chromatin and nuclear body. Predicted to be part of RNA polymerase II transcription regulator complex. Predicted to be active in nucleus. Used to study myocardial infarction. Biomarker of congenital heart disease and pulmonary hypertension. Human ortholog(s) of this gene implicated in congenital heart disease (multiple). Orthologous to human GATA4 (GATA binding protein 4). [provided by Alliance of Genome Resources, Jul 2025]
Rat Gata4 Related Products
| Product Type | Key Applications | Cat. No. | Product |
|---|---|---|---|
| Lentiviral Vector & Virus | Stable overexpression | LC621330 | View Product |
| AAV Vector & Virus | Long-term expression | VC621330 | View Product |
| Adenovirus | Transient expression | A621330 | View Product |
| CRISPR KO Tools | Gene knockout (Lentiviral) | LG621330 | View Product |
| Gene knockout (non-viral) | PG621330 | View Product | |
| Gene knockout (AAV) | VG621330 | View Product | |
| CRISPR Activation | Gene activation | LA621330 | View Product |
| siRNA Tools | Gene knockdown (Lentiviral) | LS621330 | View Product |
| Gene knockdown (AAV) | VS621330 | View Product | |
| ORF Vector | Template DNA | PC621330 | View Product |
Accelerate Discovery with Research-Ready Constructs
| Why Researchers Choose abm | Workflow Benefits |
|---|---|
| Gene-Specific Constructs | Eliminate time-consuming cloning and accelerate project timelines |
| Available as Plasmid DNA or Packaged Virus | Choose delivery format that best fits your experiment |
| Validated Sequence Design | Ensure reliable, reproducible experimental performance |
| Available in Multiple Species Options | Simplify cross-species and translational research studies |
| Flexible Customization Services | Tailor constructs with different promoters, tags, markers and other modifications |
| Expert Technical Support | Get guidance from gene delivery specialists |
Product Overview & Key Features
| System | Applications | Key Features |
|---|---|---|
| CRISPR Knockout Vectors & Viruses | Targeted gene disruption & functional knockout studies | •Pre-designed validated sgRNAs •Available in All-in-One Cas9 + sgRNA or sgRNA-only formats •Available as lentivirus, AAV and non-viral •Ideal for stable genome editing |
| Lentiviral Expression Vectors & Particles | Stable gene overexpression or delivery into difficult-to-transfect cells | •Long-term expression through genomic integration •Highly efficient in dividing and non-dividing cells •Ideal for stable cell line generation |
| AAV Vectors & Packaged Virus | In vivo delivery & transient expression with low immunogenicity | •Multiple serotypes available for tissue targeting •Excellent for animal studies and sensitive primary cells •Episomal expression with strong safety profile |
| Adenovirus | High-efficiency transient expression | •Rapid, robust gene expression •Large cargo capacity •Ideal for primary cells and strong short-term expression studies |
| ORF Vector | Template for coding sequence | •Ready-to-use full-length coding sequences •Low cost and convenient alternative to gene synthesis |
| siRNA Knockdown Tools | Temporary gene silencing & pathway validation | •Robust gene knockdown •Ideal for target validation and preliminary functional screening •Available as Lentivirus, AAV or synthetic dsRNA oligos |