GLP1R Expression Vectors, Lentivirus & CRISPR Knockout Vectors
Enhance your research with ready-to-use GLP1R-specific vectors and viral particles designed for reliable GLP1R overexpression, knockout, and silencing across a wide range of experimental systems. abm offers a complete portfolio of validated molecular tools – including GLP1R CRISPR knockout vectors, lentiviral particles, AAV vectors, adenovirus, ORF clones, and siRNA constructs for both in vitro and in vivo applications.
Human GLP1R Gene Overview
| Gene Name | glucagon like peptide 1 receptor |
|---|---|
| Gene Symbol | GLP1R |
| Synonyms | GLP-1,GLP-1R,GLP-1-R |
| NCBI ID | 2740 |
| Ensembl ID | ENSG00000112164 |
| Uniprot ID | P43220 |
| Gene Type | Protein coding |
Gene Summary
This gene encodes a 7-transmembrane receptor for glucagon-like peptide 1 (GLP-1), which stimulates glucose-dependent insulin secretion. The receptor, located on the cell surface, is internalized upon ligand binding and triggers signaling pathways that regulate insulin release, appetite, gastric emptying, and energy balance. It also has neuroprotective and cardiovascular effects. Polymorphisms in this gene are linked to type 2 diabetes risk, and the receptor is a key drug target for diabetes, obesity, and stroke therapies. [provided by RefSeq, Mar 2026]
Human GLP1R Related Products
| Product Type | Key Applications | Cat. No. | Product |
|---|---|---|---|
| Lentiviral Vector & Virus | Stable overexpression | LC121614 | View Product |
| AAV Vector & Virus | Long-term expression | VC121614 | View Product |
| Adenovirus | Transient expression | A121614 | View Product |
| CRISPR KO Tools | Gene knockout (Lentiviral) | LG121614 | View Product |
| Gene knockout (non-viral) | PG121614 | View Product | |
| Gene knockout (AAV) | VG121614 | View Product | |
| CRISPR Activation | Gene activation | LA121614 | View Product |
| siRNA Tools | Gene knockdown (Lentiviral) | LS121614 | View Product |
| Gene knockdown (AAV) | VS121614 | View Product | |
| ORF Vector | Template DNA | PC121614 | View Product |
Mouse Glp1r Gene Overview
| Gene Name | glucagon-like peptide 1 receptor |
|---|---|
| Gene Symbol | Glp1r |
| Synonyms | GLP-1R,GLP1Rc |
| NCBI ID | 14652 |
| Ensembl ID | ENSMUSG00000024027 |
| Uniprot ID | O35659 |
| Gene Type | Protein coding |
Gene Summary
Predicted to enable glucagon receptor activity; glucagon-like peptide 1 receptor activity; and peptide hormone binding activity. Involved in several processes, including learning or memory; positive regulation of blood pressure; and response to psychosocial stress. Acts upstream of or within with a positive effect on hormone secretion. Acts upstream of or within post-translational protein targeting to membrane, translocation. Predicted to be active in plasma membrane. Is expressed in several structures, including central nervous system; genitourinary system; gut; liver; and lung. Human ortholog(s) of this gene implicated in obesity. Orthologous to human GLP1R (glucagon like peptide 1 receptor). [provided by Alliance of Genome Resources, Apr 2025]
Mouse Glp1r Related Products
| Product Type | Key Applications | Cat. No. | Product |
|---|---|---|---|
| Lentiviral Vector & Virus | Stable overexpression | LC421614 | View Product |
| AAV Vector & Virus | Long-term expression | VC421614 | View Product |
| Adenovirus | Transient expression | A421614 | View Product |
| CRISPR KO Tools | Gene knockout (Lentiviral) | LG421614 | View Product |
| Gene knockout (non-viral) | PG421614 | View Product | |
| Gene knockout (AAV) | VG421614 | View Product | |
| CRISPR Activation | Gene activation | LA421614 | View Product |
| siRNA Tools | Gene knockdown (Lentiviral) | LS421614 | View Product |
| Gene knockdown (AAV) | VS421614 | View Product | |
| ORF Vector | Template DNA | PC421614 | View Product |
Rat Glp1r Gene Overview
| Gene Name | glucagon-like peptide 1 receptor |
|---|---|
| Gene Symbol | Glp1r |
| Synonyms | Glip,RATGL1RCP |
| NCBI ID | 25051 |
| Ensembl ID | ENSRNOG00000001152 |
| Uniprot ID | P32301 |
| Gene Type | Protein coding |
Gene Summary
Enables glucagon-like peptide 1 receptor activity and peptide hormone binding activity. Involved in several processes, including cAMP/PKA signal transduction; learning or memory; and positive regulation of insulin secretion. Located in plasma membrane. Used to study hyperglycemia and hypertension. Biomarker of obesity. Human ortholog(s) of this gene implicated in obesity. Orthologous to human GLP1R (glucagon like peptide 1 receptor). [provided by Alliance of Genome Resources, Jul 2025]
Rat Glp1r Related Products
| Product Type | Key Applications | Cat. No. | Product |
|---|---|---|---|
| Lentiviral Vector & Virus | Stable overexpression | LC621614 | View Product |
| AAV Vector & Virus | Long-term expression | VC621614 | View Product |
| Adenovirus | Transient expression | A621614 | View Product |
| CRISPR KO Tools | Gene knockout (Lentiviral) | LG621614 | View Product |
| Gene knockout (non-viral) | PG621614 | View Product | |
| Gene knockout (AAV) | VG621614 | View Product | |
| CRISPR Activation | Gene activation | LA621614 | View Product |
| siRNA Tools | Gene knockdown (Lentiviral) | LS621614 | View Product |
| Gene knockdown (AAV) | VS621614 | View Product | |
| ORF Vector | Template DNA | PC621614 | View Product |
Accelerate Discovery with Research-Ready Constructs
| Why Researchers Choose abm | Workflow Benefits |
|---|---|
| Gene-Specific Constructs | Eliminate time-consuming cloning and accelerate project timelines |
| Available as Plasmid DNA or Packaged Virus | Choose delivery format that best fits your experiment |
| Validated Sequence Design | Ensure reliable, reproducible experimental performance |
| Available in Multiple Species Options | Simplify cross-species and translational research studies |
| Flexible Customization Services | Tailor constructs with different promoters, tags, markers and other modifications |
| Expert Technical Support | Get guidance from gene delivery specialists |
Product Overview & Key Features
| System | Applications | Key Features |
|---|---|---|
| CRISPR Knockout Vectors & Viruses | Targeted gene disruption & functional knockout studies | •Pre-designed validated sgRNAs •Available in All-in-One Cas9 + sgRNA or sgRNA-only formats •Available as lentivirus, AAV and non-viral •Ideal for stable genome editing |
| Lentiviral Expression Vectors & Particles | Stable gene overexpression or delivery into difficult-to-transfect cells | •Long-term expression through genomic integration •Highly efficient in dividing and non-dividing cells •Ideal for stable cell line generation |
| AAV Vectors & Packaged Virus | In vivo delivery & transient expression with low immunogenicity | •Multiple serotypes available for tissue targeting •Excellent for animal studies and sensitive primary cells •Episomal expression with strong safety profile |
| Adenovirus | High-efficiency transient expression | •Rapid, robust gene expression •Large cargo capacity •Ideal for primary cells and strong short-term expression studies |
| ORF Vector | Template for coding sequence | •Ready-to-use full-length coding sequences •Low cost and convenient alternative to gene synthesis |
| siRNA Knockdown Tools | Temporary gene silencing & pathway validation | •Robust gene knockdown •Ideal for target validation and preliminary functional screening •Available as Lentivirus, AAV or synthetic dsRNA oligos |