GPR68 Expression Vectors, Lentivirus & CRISPR Knockout Vectors
Enhance your research with ready-to-use GPR68-specific vectors and viral particles designed for reliable GPR68 overexpression, knockout, and silencing across a wide range of experimental systems. abm offers a complete portfolio of validated molecular tools – including GPR68 CRISPR knockout vectors, lentiviral particles, AAV vectors, adenovirus, ORF clones, and siRNA constructs for both in vitro and in vivo applications.
Human GPR68 Gene Overview
| Gene Name | G protein-coupled receptor 68 |
|---|---|
| Gene Symbol | GPR68 |
| Synonyms | OGR1,AI2A6,GPR12A |
| NCBI ID | 8111 |
| Ensembl ID | ENSG00000119714 |
| Uniprot ID | Q15743 |
| Gene Type | Protein coding |
Gene Summary
The protein encoded by this gene is a G protein-coupled receptor for sphingosylphosphorylcholine. The encoded protein is a proton-sensing receptor, inactive at pH 7.8 but active at pH 6.8. Mutations in this gene are a cause of amelogenesis imperfecta. [provided by RefSeq, Feb 2017]
Human GPR68 Related Products
| Product Type | Key Applications | Cat. No. | Product |
|---|---|---|---|
| Lentiviral Vector & Virus | Stable overexpression | LC122581 | View Product |
| AAV Vector & Virus | Long-term expression | VC122581 | View Product |
| Adenovirus | Transient expression | A122581 | View Product |
| CRISPR KO Tools | Gene knockout (Lentiviral) | LG122581 | View Product |
| Gene knockout (non-viral) | PG122581 | View Product | |
| Gene knockout (AAV) | VG122581 | View Product | |
| CRISPR Activation | Gene activation | LA122581 | View Product |
| siRNA Tools | Gene knockdown (Lentiviral) | LS122581 | View Product |
| Gene knockdown (AAV) | VS122581 | View Product | |
| ORF Vector | Template DNA | PC122581 | View Product |
Mouse Gpr68 Gene Overview
| Gene Name | G protein-coupled receptor 68 |
|---|---|
| Gene Symbol | Gpr68 |
| Synonyms | Ogr1 |
| NCBI ID | 238377 |
| Ensembl ID | ENSMUSG00000047415 |
| Uniprot ID | Q8BFQ3 |
| Gene Type | Protein coding |
Gene Summary
Predicted to enable G protein-coupled receptor activity. Acts upstream of or within cellular response to pH; positive regulation of insulin secretion involved in cellular response to glucose stimulus; and regulation of myeloid leukocyte differentiation. Predicted to be located in plasma membrane. Is expressed in cerebral cortex; early conceptus; primary oocyte; and secondary oocyte. Human ortholog(s) of this gene implicated in amelogenesis imperfecta type 2A6. Orthologous to human GPR68 (G protein-coupled receptor 68). [provided by Alliance of Genome Resources, Apr 2025]
Mouse Gpr68 Related Products
| Product Type | Key Applications | Cat. No. | Product |
|---|---|---|---|
| Lentiviral Vector & Virus | Stable overexpression | LC422581 | View Product |
| Stable overexpression | LC522581 | View Product | |
| AAV Vector & Virus | Long-term expression | VC422581 | View Product |
| Long-term expression | VC522581 | View Product | |
| Adenovirus | Transient expression | A422581 | View Product |
| Transient expression | A522581 | View Product | |
| CRISPR KO Tools | Gene knockout (Lentiviral) | LG422581 | View Product |
| Gene knockout (non-viral) | PG422581 | View Product | |
| Gene knockout (AAV) | VG422581 | View Product | |
| CRISPR Activation | Gene activation | LA422581 | View Product |
| siRNA Tools | Gene knockdown (Lentiviral) | LS422581 | View Product |
| Gene knockdown (AAV) | VS422581 | View Product | |
| ORF Vector | Template DNA | PC422581 | View Product |
| Template DNA | PC522581 | View Product |
Rat Gpr68 Gene Overview
| Gene Name | G protein-coupled receptor 68 |
|---|---|
| Gene Symbol | Gpr68 |
| Synonyms | |
| NCBI ID | 314386 |
| Ensembl ID | ENSRNOG00000046309 |
| Uniprot ID | |
| Gene Type | Protein coding |
Gene Summary
Predicted to enable G protein-coupled receptor activity. Predicted to be involved in cellular response to pH. Predicted to act upstream of or within negative regulation of monocyte differentiation; positive regulation of insulin secretion involved in cellular response to glucose stimulus; and positive regulation of osteoclast development. Predicted to be located in plasma membrane. Human ortholog(s) of this gene implicated in amelogenesis imperfecta type 2A6. Orthologous to human GPR68 (G protein-coupled receptor 68). [provided by Alliance of Genome Resources, Apr 2025]
Rat Gpr68 Related Products
| Product Type | Key Applications | Cat. No. | Product |
|---|---|---|---|
| Lentiviral Vector & Virus | Stable overexpression | LC622581 | View Product |
| AAV Vector & Virus | Long-term expression | VC622581 | View Product |
| Adenovirus | Transient expression | A622581 | View Product |
| CRISPR KO Tools | Gene knockout (Lentiviral) | LG622581 | View Product |
| Gene knockout (non-viral) | PG622581 | View Product | |
| Gene knockout (AAV) | VG622581 | View Product | |
| CRISPR Activation | Gene activation | LA622581 | View Product |
| siRNA Tools | Gene knockdown (Lentiviral) | LS622581 | View Product |
| Gene knockdown (AAV) | VS622581 | View Product | |
| ORF Vector | Template DNA | PC622581 | View Product |
Accelerate Discovery with Research-Ready Constructs
| Why Researchers Choose abm | Workflow Benefits |
|---|---|
| Gene-Specific Constructs | Eliminate time-consuming cloning and accelerate project timelines |
| Available as Plasmid DNA or Packaged Virus | Choose delivery format that best fits your experiment |
| Validated Sequence Design | Ensure reliable, reproducible experimental performance |
| Available in Multiple Species Options | Simplify cross-species and translational research studies |
| Flexible Customization Services | Tailor constructs with different promoters, tags, markers and other modifications |
| Expert Technical Support | Get guidance from gene delivery specialists |
Product Overview & Key Features
| System | Applications | Key Features |
|---|---|---|
| CRISPR Knockout Vectors & Viruses | Targeted gene disruption & functional knockout studies | •Pre-designed validated sgRNAs •Available in All-in-One Cas9 + sgRNA or sgRNA-only formats •Available as lentivirus, AAV and non-viral •Ideal for stable genome editing |
| Lentiviral Expression Vectors & Particles | Stable gene overexpression or delivery into difficult-to-transfect cells | •Long-term expression through genomic integration •Highly efficient in dividing and non-dividing cells •Ideal for stable cell line generation |
| AAV Vectors & Packaged Virus | In vivo delivery & transient expression with low immunogenicity | •Multiple serotypes available for tissue targeting •Excellent for animal studies and sensitive primary cells •Episomal expression with strong safety profile |
| Adenovirus | High-efficiency transient expression | •Rapid, robust gene expression •Large cargo capacity •Ideal for primary cells and strong short-term expression studies |
| ORF Vector | Template for coding sequence | •Ready-to-use full-length coding sequences •Low cost and convenient alternative to gene synthesis |
| siRNA Knockdown Tools | Temporary gene silencing & pathway validation | •Robust gene knockdown •Ideal for target validation and preliminary functional screening •Available as Lentivirus, AAV or synthetic dsRNA oligos |