HES1 Expression Vectors, Lentivirus & CRISPR Knockout Vectors
Enhance your research with ready-to-use HES1-specific vectors and viral particles designed for reliable HES1 overexpression, knockout, and silencing across a wide range of experimental systems. abm offers a complete portfolio of validated molecular tools – including HES1 CRISPR knockout vectors, lentiviral particles, AAV vectors, adenovirus, ORF clones, and siRNA constructs for both in vitro and in vivo applications.
Human HES1 Gene Overview
| Gene Name | hes family bHLH transcription factor 1 |
|---|---|
| Gene Symbol | HES1 |
| Synonyms | HHL,HRY,HES-1,bHLHb39 |
| NCBI ID | 3280 |
| Ensembl ID | ENSG00000114315 |
| Uniprot ID | Q14469 |
| Gene Type | Protein coding |
Gene Summary
This protein belongs to the basic helix-loop-helix family of transcription factors. It is a transcriptional repressor of genes that require a bHLH protein for their transcription. The protein has a particular type of basic domain that contains a helix interrupting protein that binds to the N-box rather than the canonical E-box. [provided by RefSeq, Jul 2008]
Human HES1 Related Products
| Product Type | Key Applications | Cat. No. | Product |
|---|---|---|---|
| Lentiviral Vector & Virus | Stable overexpression | LC123213 | View Product |
| AAV Vector & Virus | Long-term expression | VC123213 | View Product |
| Adenovirus | Transient expression | A123213 | View Product |
| CRISPR KO Tools | Gene knockout (Lentiviral) | LG123213 | View Product |
| Gene knockout (non-viral) | PG123213 | View Product | |
| Gene knockout (AAV) | VG123213 | View Product | |
| CRISPR Activation | Gene activation | LA123213 | View Product |
| siRNA Tools | Gene knockdown (Lentiviral) | LS123213 | View Product |
| Gene knockdown (AAV) | VS123213 | View Product | |
| ORF Vector | Template DNA | PC123213 | View Product |
Mouse Hes1 Gene Overview
| Gene Name | hes family bHLH transcription factor 1 |
|---|---|
| Gene Symbol | Hes1 |
| Synonyms | Hry,bHLHb39 |
| NCBI ID | 15205 |
| Ensembl ID | ENSMUSG00000022528 |
| Uniprot ID | P35428 |
| Gene Type | Protein coding |
Gene Summary
Enables several functions, including DNA-binding transcription repressor activity, RNA polymerase II-specific; HLH domain binding activity; and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in several processes, including circulatory system development; kidney development; and regulation of gliogenesis. Acts upstream of or within several processes, including hepaticobiliary system development; negative regulation of cell differentiation; and nervous system development. Located in cytoplasm and nucleus. Part of protein-containing complex. Is expressed in several structures, including alimentary system; central nervous system; embryo mesenchyme; foot bone; and sensory organ. Orthologous to human HES1 (hes family bHLH transcription factor 1). [provided by Alliance of Genome Resources, Jul 2025]
Mouse Hes1 Related Products
| Product Type | Key Applications | Cat. No. | Product |
|---|---|---|---|
| Lentiviral Vector & Virus | Stable overexpression | LC423213 | View Product |
| AAV Vector & Virus | Long-term expression | VC423213 | View Product |
| Adenovirus | Transient expression | A423213 | View Product |
| CRISPR KO Tools | Gene knockout (Lentiviral) | LG423213 | View Product |
| Gene knockout (non-viral) | PG423213 | View Product | |
| Gene knockout (AAV) | VG423213 | View Product | |
| CRISPR Activation | Gene activation | LA423213 | View Product |
| siRNA Tools | Gene knockdown (Lentiviral) | LS423213 | View Product |
| Gene knockdown (AAV) | VS423213 | View Product | |
| ORF Vector | Template DNA | PC423213 | View Product |
Rat Hes1 Gene Overview
| Gene Name | hes family bHLH transcription factor 1 |
|---|---|
| Gene Symbol | Hes1 |
| Synonyms | |
| NCBI ID | 29577 |
| Ensembl ID | ENSRNOG00000001720 |
| Uniprot ID | Q04666 |
| Gene Type | Protein coding |
Gene Summary
Enables several functions, including JUN kinase binding activity; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and transcription corepressor binding activity. Involved in several processes, including cellular response to cytokine stimulus; regulation of gene expression; and regulation of gliogenesis. Located in chromatin and nuclear matrix. Used to study chronic myeloid leukemia and epilepsy. Biomarker of acute kidney failure. Orthologous to human HES1 (hes family bHLH transcription factor 1). [provided by Alliance of Genome Resources, Jul 2025]
Rat Hes1 Related Products
| Product Type | Key Applications | Cat. No. | Product |
|---|---|---|---|
| Lentiviral Vector & Virus | Stable overexpression | LC623213 | View Product |
| AAV Vector & Virus | Long-term expression | VC623213 | View Product |
| Adenovirus | Transient expression | A623213 | View Product |
| CRISPR KO Tools | Gene knockout (Lentiviral) | LG623213 | View Product |
| Gene knockout (non-viral) | PG623213 | View Product | |
| Gene knockout (AAV) | VG623213 | View Product | |
| CRISPR Activation | Gene activation | LA623213 | View Product |
| siRNA Tools | Gene knockdown (Lentiviral) | LS623213 | View Product |
| Gene knockdown (AAV) | VS623213 | View Product | |
| ORF Vector | Template DNA | PC623213 | View Product |
Accelerate Discovery with Research-Ready Constructs
| Why Researchers Choose abm | Workflow Benefits |
|---|---|
| Gene-Specific Constructs | Eliminate time-consuming cloning and accelerate project timelines |
| Available as Plasmid DNA or Packaged Virus | Choose delivery format that best fits your experiment |
| Validated Sequence Design | Ensure reliable, reproducible experimental performance |
| Available in Multiple Species Options | Simplify cross-species and translational research studies |
| Flexible Customization Services | Tailor constructs with different promoters, tags, markers and other modifications |
| Expert Technical Support | Get guidance from gene delivery specialists |
Product Overview & Key Features
| System | Applications | Key Features |
|---|---|---|
| CRISPR Knockout Vectors & Viruses | Targeted gene disruption & functional knockout studies | •Pre-designed validated sgRNAs •Available in All-in-One Cas9 + sgRNA or sgRNA-only formats •Available as lentivirus, AAV and non-viral •Ideal for stable genome editing |
| Lentiviral Expression Vectors & Particles | Stable gene overexpression or delivery into difficult-to-transfect cells | •Long-term expression through genomic integration •Highly efficient in dividing and non-dividing cells •Ideal for stable cell line generation |
| AAV Vectors & Packaged Virus | In vivo delivery & transient expression with low immunogenicity | •Multiple serotypes available for tissue targeting •Excellent for animal studies and sensitive primary cells •Episomal expression with strong safety profile |
| Adenovirus | High-efficiency transient expression | •Rapid, robust gene expression •Large cargo capacity •Ideal for primary cells and strong short-term expression studies |
| ORF Vector | Template for coding sequence | •Ready-to-use full-length coding sequences •Low cost and convenient alternative to gene synthesis |
| siRNA Knockdown Tools | Temporary gene silencing & pathway validation | •Robust gene knockdown •Ideal for target validation and preliminary functional screening •Available as Lentivirus, AAV or synthetic dsRNA oligos |