HSF1 Expression Vectors, Lentivirus & CRISPR Knockout Vectors
Enhance your research with ready-to-use HSF1-specific vectors and viral particles designed for reliable HSF1 overexpression, knockout, and silencing across a wide range of experimental systems. abm offers a complete portfolio of validated molecular tools – including HSF1 CRISPR knockout vectors, lentiviral particles, AAV vectors, adenovirus, ORF clones, and siRNA constructs for both in vitro and in vivo applications.
Human HSF1 Gene Overview
| Gene Name | heat shock transcription factor 1 |
|---|---|
| Gene Symbol | HSF1 |
| Synonyms | HSTF1 |
| NCBI ID | 3297 |
| Ensembl ID | ENSG00000185122 |
| Uniprot ID | Q00613 |
| Gene Type | Protein coding |
Gene Summary
The product of this gene is a transcription factor that is rapidly induced after temperature stress and binds heat shock promoter elements (HSE). This protein plays a role in the regulation of lifespan. Expression of this gene is repressed by phosphorylation, which promotes binding by heat shock protein 90. [provided by RefSeq, Jul 2017]
Human HSF1 Related Products
| Product Type | Key Applications | Cat. No. | Product |
|---|---|---|---|
| Lentiviral Vector & Virus | Stable overexpression | LC123960 | View Product |
| AAV Vector & Virus | Long-term expression | VC123960 | View Product |
| Adenovirus | Transient expression | A123960 | View Product |
| CRISPR KO Tools | Gene knockout (Lentiviral) | LG123960 | View Product |
| Gene knockout (non-viral) | PG123960 | View Product | |
| Gene knockout (AAV) | VG123960 | View Product | |
| CRISPR Activation | Gene activation | LA123960 | View Product |
| siRNA Tools | Gene knockdown (Lentiviral) | LS123960 | View Product |
| Gene knockdown (AAV) | VS123960 | View Product | |
| ORF Vector | Template DNA | PC123960 | View Product |
Mouse Hsf1 Gene Overview
| Gene Name | heat shock factor 1 |
|---|---|
| Gene Symbol | Hsf1 |
| Synonyms | HSTF,HSTF 1,Hsf1beta,Hsf1alpha |
| NCBI ID | 15499 |
| Ensembl ID | ENSMUSG00000022556 |
| Uniprot ID | P38532 |
| Gene Type | Protein coding |
Gene Summary
Enables RNA polymerase II cis-regulatory region sequence-specific DNA binding activity and chromatin binding activity. Involved in positive regulation of cold-induced thermogenesis and positive regulation of gene expression. Acts upstream of or within several processes, including embryo development; negative regulation of tumor necrosis factor production; and response to lipopolysaccharide. Located in cytoplasm and pronucleus. Part of protein-containing complex. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; heart; and hemolymphoid system. Human ortholog(s) of this gene implicated in Huntington's disease. Orthologous to human HSF1 (heat shock transcription factor 1). [provided by Alliance of Genome Resources, Jul 2025]
Mouse Hsf1 Related Products
| Product Type | Key Applications | Cat. No. | Product |
|---|---|---|---|
| Lentiviral Vector & Virus | Stable overexpression | LC423960 | View Product |
| AAV Vector & Virus | Long-term expression | VC423960 | View Product |
| Adenovirus | Transient expression | A423960 | View Product |
| CRISPR KO Tools | Gene knockout (Lentiviral) | LG423960 | View Product |
| Gene knockout (non-viral) | PG423960 | View Product | |
| Gene knockout (AAV) | VG423960 | View Product | |
| CRISPR Activation | Gene activation | LA423960 | View Product |
| siRNA Tools | Gene knockdown (Lentiviral) | LS423960 | View Product |
| Gene knockdown (AAV) | VS423960 | View Product | |
| ORF Vector | Template DNA | PC423960 | View Product |
Rat Hsf1 Gene Overview
| Gene Name | heat shock transcription factor 1 |
|---|---|
| Gene Symbol | Hsf1 |
| Synonyms | |
| NCBI ID | 79245 |
| Ensembl ID | ENSRNOG00000021732 |
| Uniprot ID | |
| Gene Type | Protein coding |
Gene Summary
Enables several functions, including STAT family protein binding activity; promoter-specific chromatin binding activity; and sequence-specific single stranded DNA binding activity. Involved in several processes, including regulation of apoptotic process; regulation of inclusion body assembly; and regulation of macromolecule metabolic process. Located in euchromatin and heterochromatin. Used to study Parkinson's disease; muscular atrophy; and transient cerebral ischemia. Biomarker of Alzheimer's disease; Parkinson's disease; congestive heart failure; cryptorchidism; and transient cerebral ischemia. Human ortholog(s) of this gene implicated in Huntington's disease. Orthologous to human HSF1 (heat shock transcription factor 1). [provided by Alliance of Genome Resources, Jul 2025]
Rat Hsf1 Related Products
| Product Type | Key Applications | Cat. No. | Product |
|---|---|---|---|
| Lentiviral Vector & Virus | Stable overexpression | LC623960 | View Product |
| AAV Vector & Virus | Long-term expression | VC623960 | View Product |
| Adenovirus | Transient expression | A623960 | View Product |
| CRISPR KO Tools | Gene knockout (Lentiviral) | LG623960 | View Product |
| Gene knockout (non-viral) | PG623960 | View Product | |
| Gene knockout (AAV) | VG623960 | View Product | |
| CRISPR Activation | Gene activation | LA623960 | View Product |
| siRNA Tools | Gene knockdown (Lentiviral) | LS623960 | View Product |
| Gene knockdown (AAV) | VS623960 | View Product | |
| ORF Vector | Template DNA | PC623960 | View Product |
Accelerate Discovery with Research-Ready Constructs
| Why Researchers Choose abm | Workflow Benefits |
|---|---|
| Gene-Specific Constructs | Eliminate time-consuming cloning and accelerate project timelines |
| Available as Plasmid DNA or Packaged Virus | Choose delivery format that best fits your experiment |
| Validated Sequence Design | Ensure reliable, reproducible experimental performance |
| Available in Multiple Species Options | Simplify cross-species and translational research studies |
| Flexible Customization Services | Tailor constructs with different promoters, tags, markers and other modifications |
| Expert Technical Support | Get guidance from gene delivery specialists |
Product Overview & Key Features
| System | Applications | Key Features |
|---|---|---|
| CRISPR Knockout Vectors & Viruses | Targeted gene disruption & functional knockout studies | •Pre-designed validated sgRNAs •Available in All-in-One Cas9 + sgRNA or sgRNA-only formats •Available as lentivirus, AAV and non-viral •Ideal for stable genome editing |
| Lentiviral Expression Vectors & Particles | Stable gene overexpression or delivery into difficult-to-transfect cells | •Long-term expression through genomic integration •Highly efficient in dividing and non-dividing cells •Ideal for stable cell line generation |
| AAV Vectors & Packaged Virus | In vivo delivery & transient expression with low immunogenicity | •Multiple serotypes available for tissue targeting •Excellent for animal studies and sensitive primary cells •Episomal expression with strong safety profile |
| Adenovirus | High-efficiency transient expression | •Rapid, robust gene expression •Large cargo capacity •Ideal for primary cells and strong short-term expression studies |
| ORF Vector | Template for coding sequence | •Ready-to-use full-length coding sequences •Low cost and convenient alternative to gene synthesis |
| siRNA Knockdown Tools | Temporary gene silencing & pathway validation | •Robust gene knockdown •Ideal for target validation and preliminary functional screening •Available as Lentivirus, AAV or synthetic dsRNA oligos |