IFNAR1 Expression Vectors, Lentivirus & CRISPR Knockout Vectors
Enhance your research with ready-to-use IFNAR1-specific vectors and viral particles designed for reliable IFNAR1 overexpression, knockout, and silencing across a wide range of experimental systems. abm offers a complete portfolio of validated molecular tools – including IFNAR1 CRISPR knockout vectors, lentiviral particles, AAV vectors, adenovirus, ORF clones, and siRNA constructs for both in vitro and in vivo applications.
Human IFNAR1 Gene Overview
| Gene Name | interferon alpha and beta receptor subunit 1 |
|---|---|
| Gene Symbol | IFNAR1 |
| Synonyms | AVP,IFRC,IFNAR,IFNBR,CRF2-1,IMD106,IFN-R-1,IFN-alpha-REC |
| NCBI ID | 3454 |
| Ensembl ID | ENSG00000142166 |
| Uniprot ID | P17181 |
| Gene Type | Protein coding |
Gene Summary
The protein encoded by this gene is a type I membrane protein that forms one of the two chains of a receptor for interferons alpha and beta. Binding and activation of the receptor stimulates Janus protein kinases, which in turn phosphorylate several proteins, including STAT1 and STAT2. The protein belongs to the type II cytokine receptor family and functions as an antiviral factor. [provided by RefSeq, Jul 2020]
Human IFNAR1 Related Products
| Product Type | Key Applications | Cat. No. | Product |
|---|---|---|---|
| Lentiviral Vector & Virus | Stable overexpression | LC124264 | View Product |
| AAV Vector & Virus | Long-term expression | VC124264 | View Product |
| Adenovirus | Transient expression | A124264 | View Product |
| CRISPR KO Tools | Gene knockout (Lentiviral) | LG124264 | View Product |
| Gene knockout (non-viral) | PG124264 | View Product | |
| Gene knockout (AAV) | VG124264 | View Product | |
| CRISPR Activation | Gene activation | LA124264 | View Product |
| siRNA Tools | Gene knockdown (Lentiviral) | LS124264 | View Product |
| Gene knockdown (AAV) | VS124264 | View Product | |
| ORF Vector | Template DNA | PC124264 | View Product |
Mouse Ifnar1 Gene Overview
| Gene Name | interferon (alpha and beta) receptor 1 |
|---|---|
| Gene Symbol | Ifnar1 |
| Synonyms | Ifar,Ifrc,Ifnar,Infar |
| NCBI ID | 15975 |
| Ensembl ID | ENSMUSG00000022967 |
| Uniprot ID | P33896 |
| Gene Type | Protein coding |
Gene Summary
Enables type I interferon binding activity and type I interferon receptor activity. Involved in several processes, including cellular response to interferon-alpha; defense response to other organism; and positive regulation of macromolecule biosynthetic process. Acts upstream of or within T cell activation; positive regulation of cytokine production; and regulation of peptidyl-tyrosine phosphorylation. Located in plasma membrane. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; integumental system; and sensory organ. Human ortholog(s) of this gene implicated in hepatitis C and immunodeficiency 106. Orthologous to human IFNAR1 (interferon alpha and beta receptor subunit 1). [provided by Alliance of Genome Resources, Apr 2025]
Mouse Ifnar1 Related Products
| Product Type | Key Applications | Cat. No. | Product |
|---|---|---|---|
| Lentiviral Vector & Virus | Stable overexpression | LC424264 | View Product |
| AAV Vector & Virus | Long-term expression | VC424264 | View Product |
| Adenovirus | Transient expression | A424264 | View Product |
| CRISPR KO Tools | Gene knockout (Lentiviral) | LG424264 | View Product |
| Gene knockout (non-viral) | PG424264 | View Product | |
| Gene knockout (AAV) | VG424264 | View Product | |
| CRISPR Activation | Gene activation | LA424264 | View Product |
| siRNA Tools | Gene knockdown (Lentiviral) | LS424264 | View Product |
| Gene knockdown (AAV) | VS424264 | View Product | |
| ORF Vector | Template DNA | PC424264 | View Product |
Rat Ifnar1 Gene Overview
| Gene Name | interferon alpha and beta receptor subunit 1 |
|---|---|
| Gene Symbol | Ifnar1 |
| Synonyms | |
| NCBI ID | 288264 |
| Ensembl ID | ENSRNOG00000028594 |
| Uniprot ID | |
| Gene Type | Protein coding |
Gene Summary
Predicted to enable JAK pathway signal transduction adaptor activity; type I interferon binding activity; and type I interferon receptor activity. Involved in cytokine-mediated signaling pathway. Predicted to be part of receptor complex. Predicted to be active in plasma membrane. Human ortholog(s) of this gene implicated in hepatitis C and immunodeficiency 106. Orthologous to human IFNAR1 (interferon alpha and beta receptor subunit 1). [provided by Alliance of Genome Resources, Apr 2025]
Rat Ifnar1 Related Products
| Product Type | Key Applications | Cat. No. | Product |
|---|---|---|---|
| Lentiviral Vector & Virus | Stable overexpression | LC624264 | View Product |
| AAV Vector & Virus | Long-term expression | VC624264 | View Product |
| Adenovirus | Transient expression | A624264 | View Product |
| CRISPR KO Tools | Gene knockout (Lentiviral) | LG624264 | View Product |
| Gene knockout (non-viral) | PG624264 | View Product | |
| Gene knockout (AAV) | VG624264 | View Product | |
| CRISPR Activation | Gene activation | LA624264 | View Product |
| siRNA Tools | Gene knockdown (Lentiviral) | LS624264 | View Product |
| Gene knockdown (AAV) | VS624264 | View Product | |
| ORF Vector | Template DNA | PC624264 | View Product |
Accelerate Discovery with Research-Ready Constructs
| Why Researchers Choose abm | Workflow Benefits |
|---|---|
| Gene-Specific Constructs | Eliminate time-consuming cloning and accelerate project timelines |
| Available as Plasmid DNA or Packaged Virus | Choose delivery format that best fits your experiment |
| Validated Sequence Design | Ensure reliable, reproducible experimental performance |
| Available in Multiple Species Options | Simplify cross-species and translational research studies |
| Flexible Customization Services | Tailor constructs with different promoters, tags, markers and other modifications |
| Expert Technical Support | Get guidance from gene delivery specialists |
Product Overview & Key Features
| System | Applications | Key Features |
|---|---|---|
| CRISPR Knockout Vectors & Viruses | Targeted gene disruption & functional knockout studies | •Pre-designed validated sgRNAs •Available in All-in-One Cas9 + sgRNA or sgRNA-only formats •Available as lentivirus, AAV and non-viral •Ideal for stable genome editing |
| Lentiviral Expression Vectors & Particles | Stable gene overexpression or delivery into difficult-to-transfect cells | •Long-term expression through genomic integration •Highly efficient in dividing and non-dividing cells •Ideal for stable cell line generation |
| AAV Vectors & Packaged Virus | In vivo delivery & transient expression with low immunogenicity | •Multiple serotypes available for tissue targeting •Excellent for animal studies and sensitive primary cells •Episomal expression with strong safety profile |
| Adenovirus | High-efficiency transient expression | •Rapid, robust gene expression •Large cargo capacity •Ideal for primary cells and strong short-term expression studies |
| ORF Vector | Template for coding sequence | •Ready-to-use full-length coding sequences •Low cost and convenient alternative to gene synthesis |
| siRNA Knockdown Tools | Temporary gene silencing & pathway validation | •Robust gene knockdown •Ideal for target validation and preliminary functional screening •Available as Lentivirus, AAV or synthetic dsRNA oligos |