IL1A Expression Vectors, Lentivirus & CRISPR Knockout Vectors
Enhance your research with ready-to-use IL1A-specific vectors and viral particles designed for reliable IL1A overexpression, knockout, and silencing across a wide range of experimental systems. abm offers a complete portfolio of validated molecular tools – including IL1A CRISPR knockout vectors, lentiviral particles, AAV vectors, adenovirus, ORF clones, and siRNA constructs for both in vitro and in vivo applications.
Human IL1A Gene Overview
| Gene Name | interleukin 1 alpha |
|---|---|
| Gene Symbol | IL1A |
| Synonyms | IL1,IL-1A,IL1F1,IL1-ALPHA,IL-1 alpha |
| NCBI ID | 3552 |
| Ensembl ID | ENSG00000115008 |
| Uniprot ID | P01583 |
| Gene Type | Protein coding |
Gene Summary
The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is a pleiotropic cytokine involved in various immune responses, inflammatory processes, and hematopoiesis. This cytokine is produced by monocytes and macrophages as a proprotein, which is proteolytically processed and released in response to cell injury, and thus induces apoptosis. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. It has been suggested that the polymorphism of these genes is associated with rheumatoid arthritis and Alzheimer's disease. [provided by RefSeq, Jul 2008]
Human IL1A Related Products
| Product Type | Key Applications | Cat. No. | Product |
|---|---|---|---|
| Lentiviral Vector & Virus | Stable overexpression | LC124841 | View Product |
| AAV Vector & Virus | Long-term expression | VC124841 | View Product |
| Adenovirus | Transient expression | A124841 | View Product |
| CRISPR KO Tools | Gene knockout (Lentiviral) | LG124841 | View Product |
| Gene knockout (non-viral) | PG124841 | View Product | |
| Gene knockout (AAV) | VG124841 | View Product | |
| CRISPR Activation | Gene activation | LA124841 | View Product |
| siRNA Tools | Gene knockdown (Lentiviral) | LS124841 | View Product |
| Gene knockdown (AAV) | VS124841 | View Product | |
| ORF Vector | Template DNA | PC124841 | View Product |
Mouse Il1a Gene Overview
| Gene Name | interleukin 1 alpha |
|---|---|
| Gene Symbol | Il1a |
| Synonyms | Il-1a |
| NCBI ID | 16175 |
| Ensembl ID | ENSMUSG00000027399 |
| Uniprot ID | P01582 |
| Gene Type | Protein coding |
Gene Summary
Enables cytokine activity. Involved in positive regulation of angiogenesis and positive regulation of vascular endothelial growth factor production. Acts upstream of or within several processes, including connective tissue replacement involved in inflammatory response wound healing; ectopic germ cell programmed cell death; and extrinsic apoptotic signaling pathway in absence of ligand. Located in extracellular space. Is expressed in several structures, including alimentary system; brain; early conceptus; genitourinary system; and hemolymphoid system. Human ortholog(s) of this gene implicated in several diseases, including Fabry disease; Schnitzler syndrome; autoimmune disease (multiple); hematologic cancer (multiple); and lung disease (multiple). Orthologous to human IL1A (interleukin 1 alpha). [provided by Alliance of Genome Resources, Jul 2025]
Mouse Il1a Related Products
| Product Type | Key Applications | Cat. No. | Product |
|---|---|---|---|
| Lentiviral Vector & Virus | Stable overexpression | LC424841 | View Product |
| AAV Vector & Virus | Long-term expression | VC424841 | View Product |
| Adenovirus | Transient expression | A424841 | View Product |
| CRISPR KO Tools | Gene knockout (Lentiviral) | LG424841 | View Product |
| Gene knockout (non-viral) | PG424841 | View Product | |
| Gene knockout (AAV) | VG424841 | View Product | |
| CRISPR Activation | Gene activation | LA424841 | View Product |
| siRNA Tools | Gene knockdown (Lentiviral) | LS424841 | View Product |
| Gene knockdown (AAV) | VS424841 | View Product | |
| ORF Vector | Template DNA | PC424841 | View Product |
Rat Il1a Gene Overview
| Gene Name | interleukin 1 alpha |
|---|---|
| Gene Symbol | Il1a |
| Synonyms | IL-1F1,IL-1 alpha |
| NCBI ID | 24493 |
| Ensembl ID | ENSRNOG00000004575 |
| Uniprot ID | P16598 |
| Gene Type | Protein coding |
Gene Summary
Predicted to enable copper ion binding activity and cytokine activity. Involved in several processes, including negative regulation of establishment of Sertoli cell barrier; positive regulation of intracellular signal transduction; and response to benzene. Located in cell surface and extracellular space. Used to study interstitial lung disease. Biomarker of several diseases, including endometritis; lung disease (multiple); urinary tract infection; uveitis; and varicocele. Human ortholog(s) of this gene implicated in several diseases, including Fabry disease; Schnitzler syndrome; autoimmune disease (multiple); hematologic cancer (multiple); and lung disease (multiple). Orthologous to human IL1A (interleukin 1 alpha). [provided by Alliance of Genome Resources, Jul 2025]
Rat Il1a Related Products
| Product Type | Key Applications | Cat. No. | Product |
|---|---|---|---|
| Lentiviral Vector & Virus | Stable overexpression | LC624841 | View Product |
| AAV Vector & Virus | Long-term expression | VC624841 | View Product |
| Adenovirus | Transient expression | A624841 | View Product |
| CRISPR KO Tools | Gene knockout (Lentiviral) | LG624841 | View Product |
| Gene knockout (non-viral) | PG624841 | View Product | |
| Gene knockout (AAV) | VG624841 | View Product | |
| CRISPR Activation | Gene activation | LA624841 | View Product |
| siRNA Tools | Gene knockdown (Lentiviral) | LS624841 | View Product |
| Gene knockdown (AAV) | VS624841 | View Product | |
| ORF Vector | Template DNA | PC624841 | View Product |
Accelerate Discovery with Research-Ready Constructs
| Why Researchers Choose abm | Workflow Benefits |
|---|---|
| Gene-Specific Constructs | Eliminate time-consuming cloning and accelerate project timelines |
| Available as Plasmid DNA or Packaged Virus | Choose delivery format that best fits your experiment |
| Validated Sequence Design | Ensure reliable, reproducible experimental performance |
| Available in Multiple Species Options | Simplify cross-species and translational research studies |
| Flexible Customization Services | Tailor constructs with different promoters, tags, markers and other modifications |
| Expert Technical Support | Get guidance from gene delivery specialists |
Product Overview & Key Features
| System | Applications | Key Features |
|---|---|---|
| CRISPR Knockout Vectors & Viruses | Targeted gene disruption & functional knockout studies | •Pre-designed validated sgRNAs •Available in All-in-One Cas9 + sgRNA or sgRNA-only formats •Available as lentivirus, AAV and non-viral •Ideal for stable genome editing |
| Lentiviral Expression Vectors & Particles | Stable gene overexpression or delivery into difficult-to-transfect cells | •Long-term expression through genomic integration •Highly efficient in dividing and non-dividing cells •Ideal for stable cell line generation |
| AAV Vectors & Packaged Virus | In vivo delivery & transient expression with low immunogenicity | •Multiple serotypes available for tissue targeting •Excellent for animal studies and sensitive primary cells •Episomal expression with strong safety profile |
| Adenovirus | High-efficiency transient expression | •Rapid, robust gene expression •Large cargo capacity •Ideal for primary cells and strong short-term expression studies |
| ORF Vector | Template for coding sequence | •Ready-to-use full-length coding sequences •Low cost and convenient alternative to gene synthesis |
| siRNA Knockdown Tools | Temporary gene silencing & pathway validation | •Robust gene knockdown •Ideal for target validation and preliminary functional screening •Available as Lentivirus, AAV or synthetic dsRNA oligos |