IL33 Expression Vectors, Lentivirus & CRISPR Knockout Vectors
Enhance your research with ready-to-use IL33-specific vectors and viral particles designed for reliable IL33 overexpression, knockout, and silencing across a wide range of experimental systems. abm offers a complete portfolio of validated molecular tools – including IL33 CRISPR knockout vectors, lentiviral particles, AAV vectors, adenovirus, ORF clones, and siRNA constructs for both in vitro and in vivo applications.
Human IL33 Gene Overview
| Gene Name | interleukin 33 |
|---|---|
| Gene Symbol | IL33 |
| Synonyms | DVS27,IL1F11,NF-HEV,NFEHEV,C9orf26 |
| NCBI ID | 90865 |
| Ensembl ID | ENSG00000137033 |
| Uniprot ID | O95760 |
| Gene Type | Protein coding |
Gene Summary
The protein encoded by this gene is a cytokine that binds to the IL1RL1/ST2 receptor. The encoded protein is involved in the maturation of Th2 cells and the activation of mast cells, basophils, eosinophils and natural killer cells. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2015]
Human IL33 Related Products
| Product Type | Key Applications | Cat. No. | Product |
|---|---|---|---|
| Lentiviral Vector & Virus | Stable overexpression | LC124885 | View Product |
| AAV Vector & Virus | Long-term expression | VC124885 | View Product |
| Adenovirus | Transient expression | A124885 | View Product |
| CRISPR KO Tools | Gene knockout (Lentiviral) | LG124885 | View Product |
| Gene knockout (non-viral) | PG124885 | View Product | |
| Gene knockout (AAV) | VG124885 | View Product | |
| CRISPR Activation | Gene activation | LA124885 | View Product |
| siRNA Tools | Gene knockdown (Lentiviral) | LS124885 | View Product |
| Gene knockdown (AAV) | VS124885 | View Product | |
| ORF Vector | Template DNA | PC124885 | View Product |
Mouse Il33 Gene Overview
| Gene Name | interleukin 33 |
|---|---|
| Gene Symbol | Il33 |
| Synonyms | Il-33,Il1f11,NF-HEV,9230117N10Rik |
| NCBI ID | 77125 |
| Ensembl ID | ENSMUSG00000024810 |
| Uniprot ID | Q8BVZ5 |
| Gene Type | Protein coding |
Gene Summary
Enables cytokine activity and interleukin-33 receptor binding activity. Involved in several processes, including antibacterial innate immune response; regulation of gene expression; and regulation of inflammatory response. Acts upstream of or within several processes, including negative regulation of macrophage proliferation; positive regulation of cellular defense response; and positive regulation of macromolecule metabolic process. Located in nucleus. Is active in extracellular space. Is expressed in several structures, including alimentary system; genitourinary system; integumental system; nervous system; and sensory organ. Used to study Alzheimer's disease. Human ortholog(s) of this gene implicated in candidiasis; inflammatory bowel disease; and peptic ulcer disease. Orthologous to human IL33 (interleukin 33). [provided by Alliance of Genome Resources, Jul 2025]
Mouse Il33 Related Products
| Product Type | Key Applications | Cat. No. | Product |
|---|---|---|---|
| Lentiviral Vector & Virus | Stable overexpression | LC424885 | View Product |
| Stable overexpression | LC524885 | View Product | |
| AAV Vector & Virus | Long-term expression | VC424885 | View Product |
| Long-term expression | VC524885 | View Product | |
| Adenovirus | Transient expression | A424885 | View Product |
| CRISPR KO Tools | Gene knockout (Lentiviral) | LG424885 | View Product |
| Gene knockout (non-viral) | PG424885 | View Product | |
| Gene knockout (AAV) | VG424885 | View Product | |
| CRISPR Activation | Gene activation | LA424885 | View Product |
| siRNA Tools | Gene knockdown (Lentiviral) | LS424885 | View Product |
| Gene knockdown (AAV) | VS424885 | View Product | |
| ORF Vector | Template DNA | PC424885 | View Product |
| Template DNA | PC524885 | View Product |
Rat Il33 Gene Overview
| Gene Name | interleukin 33 |
|---|---|
| Gene Symbol | Il33 |
| Synonyms | RGD1311155 |
| NCBI ID | 361749 |
| Ensembl ID | ENSRNOG00000016456 |
| Uniprot ID | Q66H70 |
| Gene Type | Protein coding |
Gene Summary
Predicted to enable cytokine activity and interleukin-33 receptor binding activity. Involved in cellular response to mechanical stimulus and positive regulation of oligodendrocyte differentiation. Predicted to be located in cytoplasm and nucleoplasm. Predicted to be active in extracellular space. Biomarker of acute myocardial infarction; colon cancer; and diabetes mellitus. Human ortholog(s) of this gene implicated in candidiasis; inflammatory bowel disease; and peptic ulcer disease. Orthologous to human IL33 (interleukin 33). [provided by Alliance of Genome Resources, Jul 2025]
Rat Il33 Related Products
| Product Type | Key Applications | Cat. No. | Product |
|---|---|---|---|
| Lentiviral Vector & Virus | Stable overexpression | LC624885 | View Product |
| AAV Vector & Virus | Long-term expression | VC624885 | View Product |
| Adenovirus | Transient expression | A624885 | View Product |
| CRISPR KO Tools | Gene knockout (Lentiviral) | LG624885 | View Product |
| Gene knockout (non-viral) | PG624885 | View Product | |
| Gene knockout (AAV) | VG624885 | View Product | |
| CRISPR Activation | Gene activation | LA624885 | View Product |
| siRNA Tools | Gene knockdown (Lentiviral) | LS624885 | View Product |
| Gene knockdown (AAV) | VS624885 | View Product | |
| ORF Vector | Template DNA | PC624885 | View Product |
Accelerate Discovery with Research-Ready Constructs
| Why Researchers Choose abm | Workflow Benefits |
|---|---|
| Gene-Specific Constructs | Eliminate time-consuming cloning and accelerate project timelines |
| Available as Plasmid DNA or Packaged Virus | Choose delivery format that best fits your experiment |
| Validated Sequence Design | Ensure reliable, reproducible experimental performance |
| Available in Multiple Species Options | Simplify cross-species and translational research studies |
| Flexible Customization Services | Tailor constructs with different promoters, tags, markers and other modifications |
| Expert Technical Support | Get guidance from gene delivery specialists |
Product Overview & Key Features
| System | Applications | Key Features |
|---|---|---|
| CRISPR Knockout Vectors & Viruses | Targeted gene disruption & functional knockout studies | •Pre-designed validated sgRNAs •Available in All-in-One Cas9 + sgRNA or sgRNA-only formats •Available as lentivirus, AAV and non-viral •Ideal for stable genome editing |
| Lentiviral Expression Vectors & Particles | Stable gene overexpression or delivery into difficult-to-transfect cells | •Long-term expression through genomic integration •Highly efficient in dividing and non-dividing cells •Ideal for stable cell line generation |
| AAV Vectors & Packaged Virus | In vivo delivery & transient expression with low immunogenicity | •Multiple serotypes available for tissue targeting •Excellent for animal studies and sensitive primary cells •Episomal expression with strong safety profile |
| Adenovirus | High-efficiency transient expression | •Rapid, robust gene expression •Large cargo capacity •Ideal for primary cells and strong short-term expression studies |
| ORF Vector | Template for coding sequence | •Ready-to-use full-length coding sequences •Low cost and convenient alternative to gene synthesis |
| siRNA Knockdown Tools | Temporary gene silencing & pathway validation | •Robust gene knockdown •Ideal for target validation and preliminary functional screening •Available as Lentivirus, AAV or synthetic dsRNA oligos |