IRF7 Expression Vectors, Lentivirus & CRISPR Knockout Vectors
Enhance your research with ready-to-use IRF7-specific vectors and viral particles designed for reliable IRF7 overexpression, knockout, and silencing across a wide range of experimental systems. abm offers a complete portfolio of validated molecular tools – including IRF7 CRISPR knockout vectors, lentiviral particles, AAV vectors, adenovirus, ORF clones, and siRNA constructs for both in vitro and in vivo applications.
Human IRF7 Gene Overview
| Gene Name | interferon regulatory factor 7 |
|---|---|
| Gene Symbol | IRF7 |
| Synonyms | IMD39,IRF-7,IRF7A,IRF7B,IRF7C,IRF7H,IRF-7H |
| NCBI ID | 3665 |
| Ensembl ID | ENSG00000185507 |
| Uniprot ID | Q92985 |
| Gene Type | Protein coding |
Gene Summary
This gene encodes interferon regulatory factor 7, a member of the interferon regulatory transcription factor (IRF) family. It has been shown to play a role in the transcriptional activation of virus-inducible cellular genes, including interferon beta chain genes. Inducible expression of IRF7 is largely restricted to lymphoid tissue. The encoded protein plays an important role in the innate immune response against DNA and RNA viruses. [provided by RefSeq, Jul 2021]
Human IRF7 Related Products
| Product Type | Key Applications | Cat. No. | Product |
|---|---|---|---|
| Lentiviral Vector & Virus | Stable overexpression | LC125087 | View Product |
| AAV Vector & Virus | Long-term expression | VC125087 | View Product |
| Adenovirus | Transient expression | A125087 | View Product |
| CRISPR KO Tools | Gene knockout (Lentiviral) | LG125087 | View Product |
| Gene knockout (non-viral) | PG125087 | View Product | |
| Gene knockout (AAV) | VG125087 | View Product | |
| CRISPR Activation | Gene activation | LA125087 | View Product |
| siRNA Tools | Gene knockdown (Lentiviral) | LS125087 | View Product |
| Gene knockdown (AAV) | VS125087 | View Product | |
| ORF Vector | Template DNA | PC125087 | View Product |
Mouse Irf7 Gene Overview
| Gene Name | interferon regulatory factor 7 |
|---|---|
| Gene Symbol | Irf7 |
| Synonyms | |
| NCBI ID | 54123 |
| Ensembl ID | ENSMUSG00000025498 |
| Uniprot ID | P70434 |
| Gene Type | Protein coding |
Gene Summary
Enables DNA-binding transcription factor activity, RNA polymerase II-specific and cis-regulatory region sequence-specific DNA binding activity. Involved in defense response to other organism; positive regulation of macromolecule biosynthetic process; and regulation of toll-like receptor signaling pathway. Acts upstream of or within immunoglobulin mediated immune response; positive regulation of type I interferon-mediated signaling pathway; and regulation of gene expression. Predicted to be located in chromatin; cytosol; and nucleoplasm. Predicted to be active in nucleus. Is expressed in apical ectodermal ridge; central nervous system; embryo; liver; and ureter. Human ortholog(s) of this gene implicated in immunodeficiency 39. Orthologous to human IRF7 (interferon regulatory factor 7). [provided by Alliance of Genome Resources, Apr 2025]
Mouse Irf7 Related Products
| Product Type | Key Applications | Cat. No. | Product |
|---|---|---|---|
| Lentiviral Vector & Virus | Stable overexpression | LC425087 | View Product |
| Stable overexpression | LC525087 | View Product | |
| AAV Vector & Virus | Long-term expression | VC425087 | View Product |
| Long-term expression | VC525087 | View Product | |
| Adenovirus | Transient expression | A425087 | View Product |
| Transient expression | A525087 | View Product | |
| CRISPR KO Tools | Gene knockout (Lentiviral) | LG425087 | View Product |
| Gene knockout (non-viral) | PG425087 | View Product | |
| Gene knockout (AAV) | VG425087 | View Product | |
| CRISPR Activation | Gene activation | LA425087 | View Product |
| siRNA Tools | Gene knockdown (Lentiviral) | LS425087 | View Product |
| Gene knockdown (AAV) | VS425087 | View Product | |
| ORF Vector | Template DNA | PC425087 | View Product |
| Template DNA | PC525087 | View Product |
Rat Irf7 Gene Overview
| Gene Name | interferon regulatory factor 7 |
|---|---|
| Gene Symbol | Irf7 |
| Synonyms | |
| NCBI ID | 293624 |
| Ensembl ID | ENSRNOG00000017414 |
| Uniprot ID | |
| Gene Type | Protein coding |
Gene Summary
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in several processes, including defense response to other organism; positive regulation of macromolecule biosynthetic process; and regulation of innate immune response. Predicted to act upstream of or within immunoglobulin mediated immune response; positive regulation of type I interferon production; and positive regulation of type I interferon-mediated signaling pathway. Predicted to be located in cytosol and nucleoplasm. Predicted to be active in chromatin and nucleus. Human ortholog(s) of this gene implicated in immunodeficiency 39. Orthologous to human IRF7 (interferon regulatory factor 7). [provided by Alliance of Genome Resources, Apr 2025]
Rat Irf7 Related Products
| Product Type | Key Applications | Cat. No. | Product |
|---|---|---|---|
| Lentiviral Vector & Virus | Stable overexpression | LC625087 | View Product |
| AAV Vector & Virus | Long-term expression | VC625087 | View Product |
| Adenovirus | Transient expression | A625087 | View Product |
| CRISPR KO Tools | Gene knockout (Lentiviral) | LG625087 | View Product |
| Gene knockout (non-viral) | PG625087 | View Product | |
| Gene knockout (AAV) | VG625087 | View Product | |
| CRISPR Activation | Gene activation | LA625087 | View Product |
| siRNA Tools | Gene knockdown (Lentiviral) | LS625087 | View Product |
| Gene knockdown (AAV) | VS625087 | View Product | |
| ORF Vector | Template DNA | PC625087 | View Product |
Accelerate Discovery with Research-Ready Constructs
| Why Researchers Choose abm | Workflow Benefits |
|---|---|
| Gene-Specific Constructs | Eliminate time-consuming cloning and accelerate project timelines |
| Available as Plasmid DNA or Packaged Virus | Choose delivery format that best fits your experiment |
| Validated Sequence Design | Ensure reliable, reproducible experimental performance |
| Available in Multiple Species Options | Simplify cross-species and translational research studies |
| Flexible Customization Services | Tailor constructs with different promoters, tags, markers and other modifications |
| Expert Technical Support | Get guidance from gene delivery specialists |
Product Overview & Key Features
| System | Applications | Key Features |
|---|---|---|
| CRISPR Knockout Vectors & Viruses | Targeted gene disruption & functional knockout studies | •Pre-designed validated sgRNAs •Available in All-in-One Cas9 + sgRNA or sgRNA-only formats •Available as lentivirus, AAV and non-viral •Ideal for stable genome editing |
| Lentiviral Expression Vectors & Particles | Stable gene overexpression or delivery into difficult-to-transfect cells | •Long-term expression through genomic integration •Highly efficient in dividing and non-dividing cells •Ideal for stable cell line generation |
| AAV Vectors & Packaged Virus | In vivo delivery & transient expression with low immunogenicity | •Multiple serotypes available for tissue targeting •Excellent for animal studies and sensitive primary cells •Episomal expression with strong safety profile |
| Adenovirus | High-efficiency transient expression | •Rapid, robust gene expression •Large cargo capacity •Ideal for primary cells and strong short-term expression studies |
| ORF Vector | Template for coding sequence | •Ready-to-use full-length coding sequences •Low cost and convenient alternative to gene synthesis |
| siRNA Knockdown Tools | Temporary gene silencing & pathway validation | •Robust gene knockdown •Ideal for target validation and preliminary functional screening •Available as Lentivirus, AAV or synthetic dsRNA oligos |