KDM1A Expression Vectors, Lentivirus & CRISPR Knockout Vectors
Enhance your research with ready-to-use KDM1A-specific vectors and viral particles designed for reliable KDM1A overexpression, knockout, and silencing across a wide range of experimental systems. abm offers a complete portfolio of validated molecular tools – including KDM1A CRISPR knockout vectors, lentiviral particles, AAV vectors, adenovirus, ORF clones, and siRNA constructs for both in vitro and in vivo applications.
Human KDM1A Gene Overview
| Gene Name | lysine demethylase 1A |
|---|---|
| Gene Symbol | KDM1A |
| Synonyms | AOF2,CPRF,KDM1,LSD1,AIMAH3,BHC110 |
| NCBI ID | 23028 |
| Ensembl ID | ENSG00000004487 |
| Uniprot ID | O60341 |
| Gene Type | Protein coding |
Gene Summary
This gene encodes a nuclear protein containing a SWIRM domain, a FAD-binding motif, and an amine oxidase domain. This protein is a component of several histone deacetylase complexes, though it silences genes by functioning as a histone demethylase. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2009]
Human KDM1A Related Products
| Product Type | Key Applications | Cat. No. | Product |
|---|---|---|---|
| Lentiviral Vector & Virus | Stable overexpression | LC125468 | View Product |
| AAV Vector & Virus | Long-term expression | VC125468 | View Product |
| Adenovirus | Transient expression | A125468 | View Product |
| CRISPR KO Tools | Gene knockout (Lentiviral) | LG125468 | View Product |
| Gene knockout (Lentiviral) | LG160835 | View Product | |
| Gene knockout (non-viral) | PG125468 | View Product | |
| Gene knockout (non-viral) | PG160835 | View Product | |
| Gene knockout (AAV) | VG125468 | View Product | |
| Gene knockout (AAV) | VG160835 | View Product | |
| CRISPR Activation | Gene activation | LA125468 | View Product |
| Gene activation | LA160835 | View Product | |
| siRNA Tools | Gene knockdown (Lentiviral) | LS125468 | View Product |
| Gene knockdown (Lentiviral) | LS160835 | View Product | |
| Gene knockdown (AAV) | VS125468 | View Product | |
| Gene knockdown (AAV) | VS160835 | View Product | |
| ORF Vector | Template DNA | PC125468 | View Product |
Mouse Kdm1a Gene Overview
| Gene Name | lysine (K)-specific demethylase 1A |
|---|---|
| Gene Symbol | Kdm1a |
| Synonyms | Aof2,Kdm1,Lsd1,mKIAA0601,D4Ertd478e,1810043O07Rik |
| NCBI ID | 99982 |
| Ensembl ID | ENSMUSG00000036940 |
| Uniprot ID | Q6ZQ88 |
| Gene Type | Protein coding |
Gene Summary
Enables several functions, including DNA-binding transcription factor binding activity; histone H3 demethylase activity; and transcription coregulator activity. Involved in several processes, including positive regulation of cell population proliferation; regulation of myeloid cell differentiation; and regulation of transcription by RNA polymerase II. Acts upstream of or within DNA repair-dependent chromatin remodeling; negative regulation of neurogenesis; and nervous system development. Located in chromatin and nucleus. Is expressed in several structures, including articular cartilage; brain; reproductive system; retina; and urinary system. Orthologous to human KDM1A (lysine demethylase 1A). [provided by Alliance of Genome Resources, Jul 2025]
Mouse Kdm1a Related Products
| Product Type | Key Applications | Cat. No. | Product |
|---|---|---|---|
| Lentiviral Vector & Virus | Stable overexpression | LC425468 | View Product |
| AAV Vector & Virus | Long-term expression | VC425468 | View Product |
| Adenovirus | Transient expression | A425468 | View Product |
| CRISPR KO Tools | Gene knockout (Lentiviral) | LG425468 | View Product |
| Gene knockout (non-viral) | PG425468 | View Product | |
| Gene knockout (AAV) | VG425468 | View Product | |
| CRISPR Activation | Gene activation | LA425468 | View Product |
| siRNA Tools | Gene knockdown (Lentiviral) | LS425468 | View Product |
| Gene knockdown (AAV) | VS425468 | View Product | |
| ORF Vector | Template DNA | PC425468 | View Product |
Rat Kdm1a Gene Overview
| Gene Name | lysine demethylase 1A |
|---|---|
| Gene Symbol | Kdm1a |
| Synonyms | Aof2,Kdm1,Lsd1,RGD1562975 |
| NCBI ID | 500569 |
| Ensembl ID | ENSRNOG00000022372 |
| Uniprot ID | A0A8I6G2K8 |
| Gene Type | Protein coding |
Gene Summary
Enables chromatin binding activity. Involved in several processes, including cellular response to cAMP; nervous system development; and positive regulation of cell size. Located in chromatin. Biomarker of breast cancer; diabetic retinopathy; schizophrenia; and transient cerebral ischemia. Orthologous to human KDM1A (lysine demethylase 1A). [provided by Alliance of Genome Resources, Jul 2025]
Rat Kdm1a Related Products
| Product Type | Key Applications | Cat. No. | Product |
|---|---|---|---|
| Lentiviral Vector & Virus | Stable overexpression | LC625468 | View Product |
| AAV Vector & Virus | Long-term expression | VC625468 | View Product |
| Adenovirus | Transient expression | A625468 | View Product |
| CRISPR KO Tools | Gene knockout (Lentiviral) | LG625468 | View Product |
| Gene knockout (non-viral) | PG625468 | View Product | |
| Gene knockout (AAV) | VG625468 | View Product | |
| CRISPR Activation | Gene activation | LA625468 | View Product |
| siRNA Tools | Gene knockdown (Lentiviral) | LS625468 | View Product |
| Gene knockdown (AAV) | VS625468 | View Product | |
| ORF Vector | Template DNA | PC625468 | View Product |
Accelerate Discovery with Research-Ready Constructs
| Why Researchers Choose abm | Workflow Benefits |
|---|---|
| Gene-Specific Constructs | Eliminate time-consuming cloning and accelerate project timelines |
| Available as Plasmid DNA or Packaged Virus | Choose delivery format that best fits your experiment |
| Validated Sequence Design | Ensure reliable, reproducible experimental performance |
| Available in Multiple Species Options | Simplify cross-species and translational research studies |
| Flexible Customization Services | Tailor constructs with different promoters, tags, markers and other modifications |
| Expert Technical Support | Get guidance from gene delivery specialists |
Product Overview & Key Features
| System | Applications | Key Features |
|---|---|---|
| CRISPR Knockout Vectors & Viruses | Targeted gene disruption & functional knockout studies | •Pre-designed validated sgRNAs •Available in All-in-One Cas9 + sgRNA or sgRNA-only formats •Available as lentivirus, AAV and non-viral •Ideal for stable genome editing |
| Lentiviral Expression Vectors & Particles | Stable gene overexpression or delivery into difficult-to-transfect cells | •Long-term expression through genomic integration •Highly efficient in dividing and non-dividing cells •Ideal for stable cell line generation |
| AAV Vectors & Packaged Virus | In vivo delivery & transient expression with low immunogenicity | •Multiple serotypes available for tissue targeting •Excellent for animal studies and sensitive primary cells •Episomal expression with strong safety profile |
| Adenovirus | High-efficiency transient expression | •Rapid, robust gene expression •Large cargo capacity •Ideal for primary cells and strong short-term expression studies |
| ORF Vector | Template for coding sequence | •Ready-to-use full-length coding sequences •Low cost and convenient alternative to gene synthesis |
| siRNA Knockdown Tools | Temporary gene silencing & pathway validation | •Robust gene knockdown •Ideal for target validation and preliminary functional screening •Available as Lentivirus, AAV or synthetic dsRNA oligos |