KHK Expression Vectors, Lentivirus & CRISPR Knockout Vectors
Enhance your research with ready-to-use KHK-specific vectors and viral particles designed for reliable KHK overexpression, knockout, and silencing across a wide range of experimental systems. abm offers a complete portfolio of validated molecular tools – including KHK CRISPR knockout vectors, lentiviral particles, AAV vectors, adenovirus, ORF clones, and siRNA constructs for both in vitro and in vivo applications.
Human KHK Gene Overview
| Gene Name | ketohexokinase |
|---|---|
| Gene Symbol | KHK |
| Synonyms | FRUCTU |
| NCBI ID | 3795 |
| Ensembl ID | ENSG00000138030 |
| Uniprot ID | P50053 |
| Gene Type | Protein coding |
Gene Summary
This gene encodes ketohexokinase that catalyzes conversion of fructose to fructose-1-phosphate. The product of this gene is the first enzyme with a specialized pathway that catabolizes dietary fructose. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
Human KHK Related Products
| Product Type | Key Applications | Cat. No. | Product |
|---|---|---|---|
| Lentiviral Vector & Virus | Stable overexpression | LC125508 | View Product |
| AAV Vector & Virus | Long-term expression | VC125508 | View Product |
| Adenovirus | Transient expression | A125508 | View Product |
| CRISPR KO Tools | Gene knockout (Lentiviral) | LG125508 | View Product |
| Gene knockout (non-viral) | PG125508 | View Product | |
| Gene knockout (AAV) | VG125508 | View Product | |
| CRISPR Activation | Gene activation | LA125508 | View Product |
| siRNA Tools | Gene knockdown (Lentiviral) | LS125508 | View Product |
| Gene knockdown (AAV) | VS125508 | View Product | |
| ORF Vector | Template DNA | PC125508 | View Product |
Mouse Khk Gene Overview
| Gene Name | ketohexokinase |
|---|---|
| Gene Symbol | Khk |
| Synonyms | |
| NCBI ID | 16548 |
| Ensembl ID | ENSMUSG00000029162 |
| Uniprot ID | P97328 |
| Gene Type | Protein coding |
Gene Summary
Enables ketohexokinase activity. Involved in fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate. Acts upstream of or within fructose metabolic process and regulation of glycogen metabolic process. Located in cytoplasm and nucleus. Is active in cytosol. Is expressed in alimentary system; central nervous system; liver; and retina. Human ortholog(s) of this gene implicated in essential fructosuria. Orthologous to human KHK (ketohexokinase). [provided by Alliance of Genome Resources, Jul 2025]
Mouse Khk Related Products
| Product Type | Key Applications | Cat. No. | Product |
|---|---|---|---|
| Lentiviral Vector & Virus | Stable overexpression | LC425508 | View Product |
| AAV Vector & Virus | Long-term expression | VC425508 | View Product |
| Adenovirus | Transient expression | A425508 | View Product |
| CRISPR KO Tools | Gene knockout (Lentiviral) | LG425508 | View Product |
| Gene knockout (non-viral) | PG425508 | View Product | |
| Gene knockout (AAV) | VG425508 | View Product | |
| CRISPR Activation | Gene activation | LA425508 | View Product |
| siRNA Tools | Gene knockdown (Lentiviral) | LS425508 | View Product |
| Gene knockdown (AAV) | VS425508 | View Product | |
| ORF Vector | Template DNA | PC425508 | View Product |
Rat Khk Gene Overview
| Gene Name | ketohexokinase |
|---|---|
| Gene Symbol | Khk |
| Synonyms | KETHPRO |
| NCBI ID | 25659 |
| Ensembl ID | ENSRNOG00000008047 |
| Uniprot ID | Q02974 |
| Gene Type | Protein coding |
Gene Summary
Enables ketohexokinase activity. Involved in several processes, including response to hexose; response to insulin; and response to sucrose. Predicted to be located in nucleus. Predicted to be active in cytosol. Human ortholog(s) of this gene implicated in essential fructosuria. Orthologous to human KHK (ketohexokinase). [provided by Alliance of Genome Resources, Jul 2025]
Rat Khk Related Products
| Product Type | Key Applications | Cat. No. | Product |
|---|---|---|---|
| Lentiviral Vector & Virus | Stable overexpression | LC625508 | View Product |
| AAV Vector & Virus | Long-term expression | VC625508 | View Product |
| Adenovirus | Transient expression | A625508 | View Product |
| CRISPR KO Tools | Gene knockout (Lentiviral) | LG625508 | View Product |
| Gene knockout (non-viral) | PG625508 | View Product | |
| Gene knockout (AAV) | VG625508 | View Product | |
| CRISPR Activation | Gene activation | LA625508 | View Product |
| siRNA Tools | Gene knockdown (Lentiviral) | LS625508 | View Product |
| Gene knockdown (AAV) | VS625508 | View Product | |
| ORF Vector | Template DNA | PC625508 | View Product |
Accelerate Discovery with Research-Ready Constructs
| Why Researchers Choose abm | Workflow Benefits |
|---|---|
| Gene-Specific Constructs | Eliminate time-consuming cloning and accelerate project timelines |
| Available as Plasmid DNA or Packaged Virus | Choose delivery format that best fits your experiment |
| Validated Sequence Design | Ensure reliable, reproducible experimental performance |
| Available in Multiple Species Options | Simplify cross-species and translational research studies |
| Flexible Customization Services | Tailor constructs with different promoters, tags, markers and other modifications |
| Expert Technical Support | Get guidance from gene delivery specialists |
Product Overview & Key Features
| System | Applications | Key Features |
|---|---|---|
| CRISPR Knockout Vectors & Viruses | Targeted gene disruption & functional knockout studies | •Pre-designed validated sgRNAs •Available in All-in-One Cas9 + sgRNA or sgRNA-only formats •Available as lentivirus, AAV and non-viral •Ideal for stable genome editing |
| Lentiviral Expression Vectors & Particles | Stable gene overexpression or delivery into difficult-to-transfect cells | •Long-term expression through genomic integration •Highly efficient in dividing and non-dividing cells •Ideal for stable cell line generation |
| AAV Vectors & Packaged Virus | In vivo delivery & transient expression with low immunogenicity | •Multiple serotypes available for tissue targeting •Excellent for animal studies and sensitive primary cells •Episomal expression with strong safety profile |
| Adenovirus | High-efficiency transient expression | •Rapid, robust gene expression •Large cargo capacity •Ideal for primary cells and strong short-term expression studies |
| ORF Vector | Template for coding sequence | •Ready-to-use full-length coding sequences •Low cost and convenient alternative to gene synthesis |
| siRNA Knockdown Tools | Temporary gene silencing & pathway validation | •Robust gene knockdown •Ideal for target validation and preliminary functional screening •Available as Lentivirus, AAV or synthetic dsRNA oligos |