LGALS3 Expression Vectors, Lentivirus & CRISPR Knockout Vectors
Enhance your research with ready-to-use LGALS3-specific vectors and viral particles designed for reliable LGALS3 overexpression, knockout, and silencing across a wide range of experimental systems. abm offers a complete portfolio of validated molecular tools – including LGALS3 CRISPR knockout vectors, lentiviral particles, AAV vectors, adenovirus, ORF clones, and siRNA constructs for both in vitro and in vivo applications.
Human LGALS3 Gene Overview
| Gene Name | galectin 3 |
|---|---|
| Gene Symbol | LGALS3 |
| Synonyms | L31,GAL3,MAC2,CBP35,GALBP,GALIG,LGALS2 |
| NCBI ID | 3958 |
| Ensembl ID | ENSG00000131981 |
| Uniprot ID | P17931 |
| Gene Type | Protein coding |
Gene Summary
This gene encodes a member of the galectin family of carbohydrate binding proteins. Members of this protein family have an affinity for beta-galactosides. The encoded protein is characterized by an N-terminal proline-rich tandem repeat domain and a single C-terminal carbohydrate recognition domain. This protein can self-associate through the N-terminal domain allowing it to bind to multivalent saccharide ligands. This protein localizes to the extracellular matrix, the cytoplasm and the nucleus. This protein plays a role in numerous cellular functions including apoptosis, innate immunity, cell adhesion and T-cell regulation. The protein exhibits antimicrobial activity against bacteria and fungi. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Oct 2014]
Human LGALS3 Related Products
| Product Type | Key Applications | Cat. No. | Product |
|---|---|---|---|
| Lentiviral Vector & Virus | Stable overexpression | LC126466 | View Product |
| AAV Vector & Virus | Long-term expression | VC126466 | View Product |
| Adenovirus | Transient expression | A126466 | View Product |
| CRISPR KO Tools | Gene knockout (Lentiviral) | LG126466 | View Product |
| Gene knockout (non-viral) | PG126466 | View Product | |
| Gene knockout (AAV) | VG126466 | View Product | |
| CRISPR Activation | Gene activation | LA126466 | View Product |
| siRNA Tools | Gene knockdown (AAV) | VS126466 | View Product |
| ORF Vector | Template DNA | PC126466 | View Product |
Mouse Lgals3 Gene Overview
| Gene Name | lectin, galactose binding, soluble 3 |
|---|---|
| Gene Symbol | Lgals3 |
| Synonyms | GBP,L-34,gal3,Mac-2 |
| NCBI ID | 16854 |
| Ensembl ID | ENSMUSG00000050335 |
| Uniprot ID | P16110 |
| Gene Type | Protein coding |
Gene Summary
Predicted to enable several functions, including IgE binding activity; advanced glycation end-product receptor activity; and signaling receptor binding activity. Involved in negative regulation of T cell receptor signaling pathway; negative regulation of endocytosis; and negative regulation of lymphocyte activation. Acts upstream of or within extracellular matrix organization and skeletal system development. Located in several cellular components, including external side of plasma membrane; glial cell projection; and immunological synapse. Is active in cornified envelope. Is expressed in several structures, including alimentary system; genitourinary system; hemolymphoid system; skeleton; and skin. Used to study steatotic liver disease. Human ortholog(s) of this gene implicated in asthma. Orthologous to human LGALS3 (galectin 3). [provided by Alliance of Genome Resources, Jul 2025]
Mouse Lgals3 Related Products
| Product Type | Key Applications | Cat. No. | Product |
|---|---|---|---|
| Lentiviral Vector & Virus | Stable overexpression | LC426466 | View Product |
| Stable overexpression | LC526466 | View Product | |
| AAV Vector & Virus | Long-term expression | VC426466 | View Product |
| Long-term expression | VC526466 | View Product | |
| Adenovirus | Transient expression | A426466 | View Product |
| Transient expression | A526466 | View Product | |
| CRISPR KO Tools | Gene knockout (Lentiviral) | LG426466 | View Product |
| Gene knockout (non-viral) | PG426466 | View Product | |
| Gene knockout (AAV) | VG426466 | View Product | |
| CRISPR Activation | Gene activation | LA426466 | View Product |
| siRNA Tools | Gene knockdown (Lentiviral) | LS426466 | View Product |
| Gene knockdown (AAV) | VS426466 | View Product | |
| ORF Vector | Template DNA | PC426466 | View Product |
| Template DNA | PC526466 | View Product |
Rat Lgals3 Gene Overview
| Gene Name | galectin 3 |
|---|---|
| Gene Symbol | Lgals3 |
| Synonyms | L-34,CBP30,gal-3,AGE-R3 |
| NCBI ID | 83781 |
| Ensembl ID | ENSRNOG00000010645 |
| Uniprot ID | P08699 |
| Gene Type | Protein coding |
Gene Summary
Enables several functions, including Fc-gamma receptor I complex binding activity; IgE binding activity; and advanced glycation end-product receptor activity. Involved in several processes, including negative regulation of cell proliferation in bone marrow; positive regulation of serotonin secretion; and response to quercetin. Located in cell surface and extracellular space. Biomarker of several diseases, including acute kidney failure; attention deficit hyperactivity disorder; brain ischemia; colon cancer; and congestive heart failure. Human ortholog(s) of this gene implicated in asthma. Orthologous to human LGALS3 (galectin 3). [provided by Alliance of Genome Resources, Apr 2025]
Rat Lgals3 Related Products
| Product Type | Key Applications | Cat. No. | Product |
|---|---|---|---|
| Lentiviral Vector & Virus | Stable overexpression | LC626466 | View Product |
| AAV Vector & Virus | Long-term expression | VC626466 | View Product |
| Adenovirus | Transient expression | A626466 | View Product |
| CRISPR KO Tools | Gene knockout (Lentiviral) | LG626466 | View Product |
| Gene knockout (non-viral) | PG626466 | View Product | |
| Gene knockout (AAV) | VG626466 | View Product | |
| CRISPR Activation | Gene activation | LA626466 | View Product |
| siRNA Tools | Gene knockdown (Lentiviral) | LS626466 | View Product |
| Gene knockdown (AAV) | VS626466 | View Product | |
| ORF Vector | Template DNA | PC626466 | View Product |
Accelerate Discovery with Research-Ready Constructs
| Why Researchers Choose abm | Workflow Benefits |
|---|---|
| Gene-Specific Constructs | Eliminate time-consuming cloning and accelerate project timelines |
| Available as Plasmid DNA or Packaged Virus | Choose delivery format that best fits your experiment |
| Validated Sequence Design | Ensure reliable, reproducible experimental performance |
| Available in Multiple Species Options | Simplify cross-species and translational research studies |
| Flexible Customization Services | Tailor constructs with different promoters, tags, markers and other modifications |
| Expert Technical Support | Get guidance from gene delivery specialists |
Product Overview & Key Features
| System | Applications | Key Features |
|---|---|---|
| CRISPR Knockout Vectors & Viruses | Targeted gene disruption & functional knockout studies | •Pre-designed validated sgRNAs •Available in All-in-One Cas9 + sgRNA or sgRNA-only formats •Available as lentivirus, AAV and non-viral •Ideal for stable genome editing |
| Lentiviral Expression Vectors & Particles | Stable gene overexpression or delivery into difficult-to-transfect cells | •Long-term expression through genomic integration •Highly efficient in dividing and non-dividing cells •Ideal for stable cell line generation |
| AAV Vectors & Packaged Virus | In vivo delivery & transient expression with low immunogenicity | •Multiple serotypes available for tissue targeting •Excellent for animal studies and sensitive primary cells •Episomal expression with strong safety profile |
| Adenovirus | High-efficiency transient expression | •Rapid, robust gene expression •Large cargo capacity •Ideal for primary cells and strong short-term expression studies |
| ORF Vector | Template for coding sequence | •Ready-to-use full-length coding sequences •Low cost and convenient alternative to gene synthesis |
| siRNA Knockdown Tools | Temporary gene silencing & pathway validation | •Robust gene knockdown •Ideal for target validation and preliminary functional screening •Available as Lentivirus, AAV or synthetic dsRNA oligos |