LIN28B Expression Vectors, Lentivirus & CRISPR Knockout Vectors
Enhance your research with ready-to-use LIN28B-specific vectors and viral particles designed for reliable LIN28B overexpression, knockout, and silencing across a wide range of experimental systems. abm offers a complete portfolio of validated molecular tools – including LIN28B CRISPR knockout vectors, lentiviral particles, AAV vectors, adenovirus, ORF clones, and siRNA constructs for both in vitro and in vivo applications.
Human LIN28B Gene Overview
| Gene Name | lin-28 RNA binding posttranscriptional regulator B |
|---|---|
| Gene Symbol | LIN28B |
| Synonyms | CSDD2 |
| NCBI ID | 389421 |
| Ensembl ID | ENSG00000187772 |
| Uniprot ID | Q6ZN17 |
| Gene Type | Protein coding |
Gene Summary
The protein encoded by this gene belongs to the lin-28 family, which is characterized by the presence of a cold-shock domain and a pair of CCHC zinc finger domains. This gene is highly expressed in testis, fetal liver, placenta, and in primary human tumors and cancer cell lines. It is negatively regulated by microRNAs that target sites in the 3' UTR, and overexpression of this gene in primary tumors is linked to the repression of let-7 family of microRNAs and derepression of let-7 targets, which facilitates cellular transformation. [provided by RefSeq, Jun 2012]
Human LIN28B Related Products
| Product Type | Key Applications | Cat. No. | Product |
|---|---|---|---|
| Lentiviral Vector & Virus | Stable overexpression | LC126553 | View Product |
| AAV Vector & Virus | Long-term expression | VC126553 | View Product |
| Adenovirus | Transient expression | A126553 | View Product |
| CRISPR KO Tools | Gene knockout (Lentiviral) | LG126553 | View Product |
| Gene knockout (non-viral) | PG126553 | View Product | |
| Gene knockout (AAV) | VG126553 | View Product | |
| CRISPR Activation | Gene activation | LA126553 | View Product |
| siRNA Tools | Gene knockdown (Lentiviral) | LS126553 | View Product |
| Gene knockdown (AAV) | VS126553 | View Product | |
| ORF Vector | Template DNA | PC126553 | View Product |
Mouse Lin28b Gene Overview
| Gene Name | lin-28 homolog B |
|---|---|
| Gene Symbol | Lin28b |
| Synonyms | Lin-28.2,2810403D23Rik,D030047M17Rik |
| NCBI ID | 380669 |
| Ensembl ID | ENSMUSG00000063804 |
| Uniprot ID | Q45KJ6 |
| Gene Type | Protein coding |
Gene Summary
Predicted to enable mRNA binding activity and sequence-specific double-stranded DNA binding activity. Predicted to be involved in RNA metabolic process and positive regulation of macromolecule metabolic process. Predicted to be located in cytosol; nucleolus; and nucleoplasm. Predicted to be active in cytoplasm and nucleus. Is expressed in several structures, including alimentary system; central nervous system; early conceptus; genitourinary system; and lumbar dorsal root ganglion. Used to study neuroblastoma. Orthologous to human LIN28B (lin-28 homolog B). [provided by Alliance of Genome Resources, Jul 2025]
Mouse Lin28b Related Products
| Product Type | Key Applications | Cat. No. | Product |
|---|---|---|---|
| Lentiviral Vector & Virus | Stable overexpression | LC426553 | View Product |
| AAV Vector & Virus | Long-term expression | VC426553 | View Product |
| Adenovirus | Transient expression | A426553 | View Product |
| CRISPR KO Tools | Gene knockout (Lentiviral) | LG426553 | View Product |
| Gene knockout (non-viral) | PG426553 | View Product | |
| Gene knockout (AAV) | VG426553 | View Product | |
| CRISPR Activation | Gene activation | LA426553 | View Product |
| siRNA Tools | Gene knockdown (Lentiviral) | LS426553 | View Product |
| Gene knockdown (AAV) | VS426553 | View Product | |
| ORF Vector | Template DNA | PC426553 | View Product |
Rat Lin28b Gene Overview
| Gene Name | lin-28 RNA binding posttranscriptional regulator B |
|---|---|
| Gene Symbol | Lin28b |
| Synonyms | |
| NCBI ID | 689054 |
| Ensembl ID | ENSRNOG00000025938 |
| Uniprot ID | |
| Gene Type | Protein coding |
Gene Summary
Predicted to enable mRNA binding activity and sequence-specific double-stranded DNA binding activity. Predicted to be involved in RNA metabolic process and positive regulation of macromolecule metabolic process. Predicted to be located in cytosol; nucleolus; and nucleoplasm. Predicted to be active in cytoplasm and nucleus. Orthologous to human LIN28B (lin-28 homolog B). [provided by Alliance of Genome Resources, Jul 2025]
Rat Lin28b Related Products
| Product Type | Key Applications | Cat. No. | Product |
|---|
Accelerate Discovery with Research-Ready Constructs
| Why Researchers Choose abm | Workflow Benefits |
|---|---|
| Gene-Specific Constructs | Eliminate time-consuming cloning and accelerate project timelines |
| Available as Plasmid DNA or Packaged Virus | Choose delivery format that best fits your experiment |
| Validated Sequence Design | Ensure reliable, reproducible experimental performance |
| Available in Multiple Species Options | Simplify cross-species and translational research studies |
| Flexible Customization Services | Tailor constructs with different promoters, tags, markers and other modifications |
| Expert Technical Support | Get guidance from gene delivery specialists |
Product Overview & Key Features
| System | Applications | Key Features |
|---|---|---|
| CRISPR Knockout Vectors & Viruses | Targeted gene disruption & functional knockout studies | •Pre-designed validated sgRNAs •Available in All-in-One Cas9 + sgRNA or sgRNA-only formats •Available as lentivirus, AAV and non-viral •Ideal for stable genome editing |
| Lentiviral Expression Vectors & Particles | Stable gene overexpression or delivery into difficult-to-transfect cells | •Long-term expression through genomic integration •Highly efficient in dividing and non-dividing cells •Ideal for stable cell line generation |
| AAV Vectors & Packaged Virus | In vivo delivery & transient expression with low immunogenicity | •Multiple serotypes available for tissue targeting •Excellent for animal studies and sensitive primary cells •Episomal expression with strong safety profile |
| Adenovirus | High-efficiency transient expression | •Rapid, robust gene expression •Large cargo capacity •Ideal for primary cells and strong short-term expression studies |
| ORF Vector | Template for coding sequence | •Ready-to-use full-length coding sequences •Low cost and convenient alternative to gene synthesis |
| siRNA Knockdown Tools | Temporary gene silencing & pathway validation | •Robust gene knockdown •Ideal for target validation and preliminary functional screening •Available as Lentivirus, AAV or synthetic dsRNA oligos |