LOXL2 Expression Vectors, Lentivirus & CRISPR Knockout Vectors
Enhance your research with ready-to-use LOXL2-specific vectors and viral particles designed for reliable LOXL2 overexpression, knockout, and silencing across a wide range of experimental systems. abm offers a complete portfolio of validated molecular tools – including LOXL2 CRISPR knockout vectors, lentiviral particles, AAV vectors, adenovirus, ORF clones, and siRNA constructs for both in vitro and in vivo applications.
Human LOXL2 Gene Overview
| Gene Name | lysyl oxidase like 2 |
|---|---|
| Gene Symbol | LOXL2 |
| Synonyms | LOR,LOR2,WS9-14 |
| NCBI ID | 4017 |
| Ensembl ID | ENSG00000134013 |
| Uniprot ID | Q9Y4K0 |
| Gene Type | Protein coding |
Gene Summary
This gene encodes a member of the lysyl oxidase gene family. The prototypic member of the family is essential to the biogenesis of connective tissue, encoding an extracellular copper-dependent amine oxidase that catalyses the first step in the formation of crosslinks in collagens and elastin. A highly conserved amino acid sequence at the C-terminus end appears to be sufficient for amine oxidase activity, suggesting that each family member may retain this function. The N-terminus is poorly conserved and may impart additional roles in developmental regulation, senescence, tumor suppression, cell growth control, and chemotaxis to each member of the family. [provided by RefSeq, Jul 2008]
Human LOXL2 Related Products
| Product Type | Key Applications | Cat. No. | Product |
|---|---|---|---|
| AAV Vector & Virus | Long-term expression | VC127543 | View Product |
| Adenovirus | Transient expression | A127543 | View Product |
| CRISPR KO Tools | Gene knockout (Lentiviral) | LG127543 | View Product |
| Gene knockout (non-viral) | PG127543 | View Product | |
| Gene knockout (AAV) | VG127543 | View Product | |
| CRISPR Activation | Gene activation | LA127543 | View Product |
| siRNA Tools | Gene knockdown (Lentiviral) | LS127543 | View Product |
| Gene knockdown (AAV) | VS127543 | View Product | |
| ORF Vector | Template DNA | PC127543 | View Product |
Mouse Loxl3 Gene Overview
| Gene Name | lysyl oxidase-like 3 |
|---|---|
| Gene Symbol | Loxl3 |
| Synonyms | Lor2,Loxl2 |
| NCBI ID | 16950 |
| Ensembl ID | ENSMUSG00000000693 |
| Uniprot ID | Q9Z175 |
| Gene Type | Protein coding |
Gene Summary
Enables fibronectin binding activity and protein-lysine 6-oxidase activity. Involved in several processes, including fibronectin fibril organization; negative regulation of T-helper 17 cell lineage commitment; and peptidyl-lysine oxidation. Located in extracellular space. Is expressed in several structures, including alimentary system; connective tissue; limb mesenchyme; sensory organ; and skeleton. Human ortholog(s) of this gene implicated in myopia. Orthologous to human LOXL3 (lysyl oxidase like 3). [provided by Alliance of Genome Resources, Jul 2025]
Mouse Loxl3 Related Products
| Product Type | Key Applications | Cat. No. | Product |
|---|---|---|---|
| Lentiviral Vector & Virus | Stable overexpression | LC427543 | View Product |
| AAV Vector & Virus | Long-term expression | VC427543 | View Product |
| Adenovirus | Transient expression | A427543 | View Product |
| CRISPR KO Tools | Gene knockout (Lentiviral) | LG427543 | View Product |
| Gene knockout (non-viral) | PG427543 | View Product | |
| Gene knockout (AAV) | VG427543 | View Product | |
| CRISPR Activation | Gene activation | LA427543 | View Product |
| siRNA Tools | Gene knockdown (Lentiviral) | LS427543 | View Product |
| Gene knockdown (AAV) | VS427543 | View Product | |
| ORF Vector | Template DNA | PC427543 | View Product |
Rat Loxl2 Gene Overview
| Gene Name | lysyl oxidase-like 2 |
|---|---|
| Gene Symbol | Loxl2 |
| Synonyms | |
| NCBI ID | 290350 |
| Ensembl ID | ENSRNOG00000016758 |
| Uniprot ID | B5DF27 |
| Gene Type | Protein coding |
Gene Summary
Predicted to enable metal ion binding activity; oligosaccharide binding activity; and protein-lysine 6-oxidase activity. Predicted to be involved in several processes, including collagen fibril organization; peptidyl-lysine oxidation; and positive regulation of cell differentiation. Located in basement membrane. Orthologous to human LOXL2 (lysyl oxidase like 2). [provided by Alliance of Genome Resources, Jul 2025]
Rat Loxl2 Related Products
| Product Type | Key Applications | Cat. No. | Product |
|---|---|---|---|
| Lentiviral Vector & Virus | Stable overexpression | LC627543 | View Product |
| AAV Vector & Virus | Long-term expression | VC627543 | View Product |
| Adenovirus | Transient expression | A627543 | View Product |
| CRISPR KO Tools | Gene knockout (Lentiviral) | LG627543 | View Product |
| Gene knockout (non-viral) | PG627543 | View Product | |
| Gene knockout (AAV) | VG627543 | View Product | |
| CRISPR Activation | Gene activation | LA627543 | View Product |
| siRNA Tools | Gene knockdown (Lentiviral) | LS627543 | View Product |
| Gene knockdown (AAV) | VS627543 | View Product | |
| ORF Vector | Template DNA | PC627543 | View Product |
Accelerate Discovery with Research-Ready Constructs
| Why Researchers Choose abm | Workflow Benefits |
|---|---|
| Gene-Specific Constructs | Eliminate time-consuming cloning and accelerate project timelines |
| Available as Plasmid DNA or Packaged Virus | Choose delivery format that best fits your experiment |
| Validated Sequence Design | Ensure reliable, reproducible experimental performance |
| Available in Multiple Species Options | Simplify cross-species and translational research studies |
| Flexible Customization Services | Tailor constructs with different promoters, tags, markers and other modifications |
| Expert Technical Support | Get guidance from gene delivery specialists |
Product Overview & Key Features
| System | Applications | Key Features |
|---|---|---|
| CRISPR Knockout Vectors & Viruses | Targeted gene disruption & functional knockout studies | •Pre-designed validated sgRNAs •Available in All-in-One Cas9 + sgRNA or sgRNA-only formats •Available as lentivirus, AAV and non-viral •Ideal for stable genome editing |
| Lentiviral Expression Vectors & Particles | Stable gene overexpression or delivery into difficult-to-transfect cells | •Long-term expression through genomic integration •Highly efficient in dividing and non-dividing cells •Ideal for stable cell line generation |
| AAV Vectors & Packaged Virus | In vivo delivery & transient expression with low immunogenicity | •Multiple serotypes available for tissue targeting •Excellent for animal studies and sensitive primary cells •Episomal expression with strong safety profile |
| Adenovirus | High-efficiency transient expression | •Rapid, robust gene expression •Large cargo capacity •Ideal for primary cells and strong short-term expression studies |
| ORF Vector | Template for coding sequence | •Ready-to-use full-length coding sequences •Low cost and convenient alternative to gene synthesis |
| siRNA Knockdown Tools | Temporary gene silencing & pathway validation | •Robust gene knockdown •Ideal for target validation and preliminary functional screening •Available as Lentivirus, AAV or synthetic dsRNA oligos |