MALAT1 Expression Vectors, Lentivirus & CRISPR Knockout Vectors
Enhance your research with ready-to-use MALAT1-specific vectors and viral particles designed for reliable MALAT1 overexpression, knockout, and silencing across a wide range of experimental systems. abm offers a complete portfolio of validated molecular tools – including MALAT1 CRISPR knockout vectors, lentiviral particles, AAV vectors, adenovirus, ORF clones, and siRNA constructs for both in vitro and in vivo applications.
Human MALAT1 Gene Overview
| Gene Name | metastasis associated lung adenocarcinoma transcript 1 |
|---|---|
| Gene Symbol | MALAT1 |
| Synonyms | HCN,NEAT2,PRO2853,miPEP-52,LINC00047,NCRNA00047 |
| NCBI ID | 378938 |
| Ensembl ID | ENSG00000251562 |
| Uniprot ID | |
| Gene Type | ncRNA |
Gene Summary
This gene produces a precursor transcript from which a long non-coding RNA is derived by RNase P cleavage of a tRNA-like small ncRNA (known as mascRNA) from its 3' end. The resultant mature transcript lacks a canonical poly(A) tail but is instead stabilized by a 3' triple helical structure. This transcript is retained in the nucleus where it is thought to form molecular scaffolds for ribonucleoprotein complexes. It may act as a transcriptional regulator for numerous genes, including some genes involved in cancer metastasis and cell migration, and it is involved in cell cycle regulation. Its upregulation in multiple cancerous tissues has been associated with the proliferation and metastasis of tumor cells. [provided by RefSeq, Mar 2015]
Human MALAT1 Related Products
| Product Type | Key Applications | Cat. No. | Product |
|---|---|---|---|
| CRISPR KO Tools | Gene knockout (Lentiviral) | LG127970 | View Product |
| Gene knockout (non-viral) | PG127970 | View Product | |
| Gene knockout (AAV) | VG127970 | View Product | |
| CRISPR Activation | Gene activation | LA127970 | View Product |
| siRNA Tools | Gene knockdown (Lentiviral) | LS127970 | View Product |
| Gene knockdown (AAV) | VS127970 | View Product | |
| ORF Vector | Template DNA | PC127970 | View Product |
Mouse Malat1 Gene Overview
| Gene Name | metastasis associated lung adenocarcinoma transcript 1 (non-coding RNA) |
|---|---|
| Gene Symbol | Malat1 |
| Synonyms | Neat2,2210401K01Rik,9430072K23Rik |
| NCBI ID | 72289 |
| Ensembl ID | ENSMUSG00000092341 |
| Uniprot ID | |
| Gene Type | ncRNA |
Gene Summary
This gene produces a long non-coding RNA that is cleaved into a mature, functional transcript as well as a small cytoplasmic RNA (mascRNA). The mature transcript is stabilized by a 3' triple helical structure and is retained in the nucleus. This transcript functions in the regulation of gene expression and proliferation and may be upregulated in tumors. [provided by RefSeq, Nov 2016]
Mouse Malat1 Related Products
| Product Type | Key Applications | Cat. No. | Product |
|---|
Rat Map2k1 Gene Overview
| Gene Name | mitogen activated protein kinase kinase 1 |
|---|---|
| Gene Symbol | Map2k1 |
| Synonyms | Mek1 |
| NCBI ID | 170851 |
| Ensembl ID | ENSRNOG00000010176 |
| Uniprot ID | Q01986 |
| Gene Type | Protein coding |
Gene Summary
Enables ATP binding activity; MAP kinase kinase activity; and enzyme binding activity. Involved in several processes, including positive regulation of metabolic process; regulation of intracellular signal transduction; and regulation of muscle contraction. Acts upstream of or within positive regulation of Ras protein signal transduction. Located in several cellular components, including dendrite cytoplasm; perikaryon; and perinuclear region of cytoplasm. Is active in glutamatergic synapse and postsynaptic density. Used to study cataract and prostate adenocarcinoma. Human ortholog(s) of this gene implicated in carcinoma (multiple); cardiofaciocutaneous syndrome 3; high grade glioma; and melorheostosis. Orthologous to human MAP2K1 (mitogen-activated protein kinase kinase 1). [provided by Alliance of Genome Resources, Jul 2025]
Rat Map2k1 Related Products
| Product Type | Key Applications | Cat. No. | Product |
|---|
Accelerate Discovery with Research-Ready Constructs
| Why Researchers Choose abm | Workflow Benefits |
|---|---|
| Gene-Specific Constructs | Eliminate time-consuming cloning and accelerate project timelines |
| Available as Plasmid DNA or Packaged Virus | Choose delivery format that best fits your experiment |
| Validated Sequence Design | Ensure reliable, reproducible experimental performance |
| Available in Multiple Species Options | Simplify cross-species and translational research studies |
| Flexible Customization Services | Tailor constructs with different promoters, tags, markers and other modifications |
| Expert Technical Support | Get guidance from gene delivery specialists |
Product Overview & Key Features
| System | Applications | Key Features |
|---|---|---|
| CRISPR Knockout Vectors & Viruses | Targeted gene disruption & functional knockout studies | •Pre-designed validated sgRNAs •Available in All-in-One Cas9 + sgRNA or sgRNA-only formats •Available as lentivirus, AAV and non-viral •Ideal for stable genome editing |
| Lentiviral Expression Vectors & Particles | Stable gene overexpression or delivery into difficult-to-transfect cells | •Long-term expression through genomic integration •Highly efficient in dividing and non-dividing cells •Ideal for stable cell line generation |
| AAV Vectors & Packaged Virus | In vivo delivery & transient expression with low immunogenicity | •Multiple serotypes available for tissue targeting •Excellent for animal studies and sensitive primary cells •Episomal expression with strong safety profile |
| Adenovirus | High-efficiency transient expression | •Rapid, robust gene expression •Large cargo capacity •Ideal for primary cells and strong short-term expression studies |
| ORF Vector | Template for coding sequence | •Ready-to-use full-length coding sequences •Low cost and convenient alternative to gene synthesis |
| siRNA Knockdown Tools | Temporary gene silencing & pathway validation | •Robust gene knockdown •Ideal for target validation and preliminary functional screening •Available as Lentivirus, AAV or synthetic dsRNA oligos |