MAVS Expression Vectors, Lentivirus & CRISPR Knockout Vectors
Enhance your research with ready-to-use MAVS-specific vectors and viral particles designed for reliable MAVS overexpression, knockout, and silencing across a wide range of experimental systems. abm offers a complete portfolio of validated molecular tools – including MAVS CRISPR knockout vectors, lentiviral particles, AAV vectors, adenovirus, ORF clones, and siRNA constructs for both in vitro and in vivo applications.
Human MAVS Gene Overview
| Gene Name | mitochondrial antiviral signaling protein |
|---|---|
| Gene Symbol | MAVS |
| Synonyms | IPS1,VISA,IPS-1,CARDIF |
| NCBI ID | 57506 |
| Ensembl ID | ENSG00000088888 |
| Uniprot ID | Q7Z434 |
| Gene Type | Protein coding |
Gene Summary
This gene encodes an intermediary protein necessary in the virus-triggered beta interferon signaling pathways. It is required for activation of transcription factors which regulate expression of beta interferon and contributes to antiviral innate immunity. [provided by RefSeq, Jul 2020]
Human MAVS Related Products
| Product Type | Key Applications | Cat. No. | Product |
|---|---|---|---|
| Lentiviral Vector & Virus | Stable overexpression | LC128153 | View Product |
| AAV Vector & Virus | Long-term expression | VC128153 | View Product |
| Adenovirus | Transient expression | A128153 | View Product |
| CRISPR KO Tools | Gene knockout (Lentiviral) | LG128153 | View Product |
| Gene knockout (non-viral) | PG128153 | View Product | |
| Gene knockout (AAV) | VG128153 | View Product | |
| CRISPR Activation | Gene activation | LA128153 | View Product |
| siRNA Tools | Gene knockdown (Lentiviral) | LS128153 | View Product |
| Gene knockdown (AAV) | VS128153 | View Product | |
| ORF Vector | Template DNA | PC128153 | View Product |
Mouse Mavs Gene Overview
| Gene Name | mitochondrial antiviral signaling protein |
|---|---|
| Gene Symbol | Mavs |
| Synonyms | Visa,IPS-1,cardif,D430028G21Rik |
| NCBI ID | 228607 |
| Ensembl ID | ENSMUSG00000037523 |
| Uniprot ID | Q8VCF0 |
| Gene Type | Protein coding |
Gene Summary
Enables signaling adaptor activity. Involved in several processes, including negative regulation of viral genome replication; positive regulation of NLRP3 inflammasome complex assembly; and positive regulation of myeloid dendritic cell cytokine production. Acts upstream of or within positive regulation of cytokine production and regulation of defense response. Located in mitochondrion and peroxisome. Is expressed in cerebral cortex ventricular layer. Orthologous to human MAVS (mitochondrial antiviral signaling protein). [provided by Alliance of Genome Resources, Jul 2025]
Mouse Mavs Related Products
| Product Type | Key Applications | Cat. No. | Product |
|---|---|---|---|
| Lentiviral Vector & Virus | Stable overexpression | LC428153 | View Product |
| Stable overexpression | LC528153 | View Product | |
| AAV Vector & Virus | Long-term expression | VC428153 | View Product |
| Long-term expression | VC528153 | View Product | |
| Adenovirus | Transient expression | A428153 | View Product |
| Transient expression | A528153 | View Product | |
| CRISPR KO Tools | Gene knockout (Lentiviral) | LG428153 | View Product |
| Gene knockout (non-viral) | PG428153 | View Product | |
| Gene knockout (AAV) | VG428153 | View Product | |
| CRISPR Activation | Gene activation | LA428153 | View Product |
| siRNA Tools | Gene knockdown (Lentiviral) | LS428153 | View Product |
| Gene knockdown (AAV) | VS428153 | View Product | |
| ORF Vector | Template DNA | PC428153 | View Product |
| Template DNA | PC528153 | View Product |
Rat Mavs Gene Overview
| Gene Name | mitochondrial antiviral signaling protein |
|---|---|
| Gene Symbol | Mavs |
| Synonyms | Visa |
| NCBI ID | 311430 |
| Ensembl ID | ENSRNOG00000025295 |
| Uniprot ID | Q66HG9 |
| Gene Type | Protein coding |
Gene Summary
Predicted to enable several functions, including CARD domain binding activity; RIG-I binding activity; and molecular condensate scaffold activity. Predicted to be involved in several processes, including positive regulation of cytokine production; regulation of DNA-templated transcription; and regulation of defense response. Predicted to act upstream of or within RIG-I signaling pathway and positive regulation of type I interferon production. Predicted to be located in mitochondrion and peroxisomal membrane. Predicted to be active in mitochondrial outer membrane. Orthologous to human MAVS (mitochondrial antiviral signaling protein). [provided by Alliance of Genome Resources, Apr 2025]
Rat Mavs Related Products
| Product Type | Key Applications | Cat. No. | Product |
|---|---|---|---|
| Lentiviral Vector & Virus | Stable overexpression | LC628153 | View Product |
| AAV Vector & Virus | Long-term expression | VC628153 | View Product |
| Adenovirus | Transient expression | A628153 | View Product |
| CRISPR KO Tools | Gene knockout (Lentiviral) | LG628153 | View Product |
| Gene knockout (non-viral) | PG628153 | View Product | |
| Gene knockout (AAV) | VG628153 | View Product | |
| CRISPR Activation | Gene activation | LA628153 | View Product |
| siRNA Tools | Gene knockdown (Lentiviral) | LS628153 | View Product |
| Gene knockdown (AAV) | VS628153 | View Product | |
| ORF Vector | Template DNA | PC628153 | View Product |
Accelerate Discovery with Research-Ready Constructs
| Why Researchers Choose abm | Workflow Benefits |
|---|---|
| Gene-Specific Constructs | Eliminate time-consuming cloning and accelerate project timelines |
| Available as Plasmid DNA or Packaged Virus | Choose delivery format that best fits your experiment |
| Validated Sequence Design | Ensure reliable, reproducible experimental performance |
| Available in Multiple Species Options | Simplify cross-species and translational research studies |
| Flexible Customization Services | Tailor constructs with different promoters, tags, markers and other modifications |
| Expert Technical Support | Get guidance from gene delivery specialists |
Product Overview & Key Features
| System | Applications | Key Features |
|---|---|---|
| CRISPR Knockout Vectors & Viruses | Targeted gene disruption & functional knockout studies | •Pre-designed validated sgRNAs •Available in All-in-One Cas9 + sgRNA or sgRNA-only formats •Available as lentivirus, AAV and non-viral •Ideal for stable genome editing |
| Lentiviral Expression Vectors & Particles | Stable gene overexpression or delivery into difficult-to-transfect cells | •Long-term expression through genomic integration •Highly efficient in dividing and non-dividing cells •Ideal for stable cell line generation |
| AAV Vectors & Packaged Virus | In vivo delivery & transient expression with low immunogenicity | •Multiple serotypes available for tissue targeting •Excellent for animal studies and sensitive primary cells •Episomal expression with strong safety profile |
| Adenovirus | High-efficiency transient expression | •Rapid, robust gene expression •Large cargo capacity •Ideal for primary cells and strong short-term expression studies |
| ORF Vector | Template for coding sequence | •Ready-to-use full-length coding sequences •Low cost and convenient alternative to gene synthesis |
| siRNA Knockdown Tools | Temporary gene silencing & pathway validation | •Robust gene knockdown •Ideal for target validation and preliminary functional screening •Available as Lentivirus, AAV or synthetic dsRNA oligos |