MEF2C Expression Vectors, Lentivirus & CRISPR Knockout Vectors
Enhance your research with ready-to-use MEF2C-specific vectors and viral particles designed for reliable MEF2C overexpression, knockout, and silencing across a wide range of experimental systems. abm offers a complete portfolio of validated molecular tools – including MEF2C CRISPR knockout vectors, lentiviral particles, AAV vectors, adenovirus, ORF clones, and siRNA constructs for both in vitro and in vivo applications.
Human MEF2C Gene Overview
| Gene Name | myocyte enhancer factor 2C |
|---|---|
| Gene Symbol | MEF2C |
| Synonyms | NEDHSIL,DEL5q14.3,C5DELq14.3 |
| NCBI ID | 4208 |
| Ensembl ID | ENSG00000081189 |
| Uniprot ID | Q06413 |
| Gene Type | Protein coding |
Gene Summary
This locus encodes a member of the MADS box transcription enhancer factor 2 (MEF2) family of proteins, which play a role in myogenesis. The encoded protein, MEF2 polypeptide C, has both trans-activating and DNA binding activities. This protein may play a role in maintaining the differentiated state of muscle cells. Mutations and deletions at this locus have been associated with severe cognitive disability, stereotypic movements, epilepsy, and cerebral malformation. Alternatively spliced transcript variants have been described. [provided by RefSeq, Jul 2010]
Human MEF2C Related Products
| Product Type | Key Applications | Cat. No. | Product |
|---|---|---|---|
| Lentiviral Vector & Virus | Stable overexpression | LC128327 | View Product |
| AAV Vector & Virus | Long-term expression | VC128327 | View Product |
| Adenovirus | Transient expression | A128327 | View Product |
| CRISPR KO Tools | Gene knockout (Lentiviral) | LG128327 | View Product |
| Gene knockout (non-viral) | PG128327 | View Product | |
| Gene knockout (AAV) | VG128327 | View Product | |
| CRISPR Activation | Gene activation | LA128327 | View Product |
| siRNA Tools | Gene knockdown (Lentiviral) | LS128327 | View Product |
| Gene knockdown (AAV) | VS128327 | View Product | |
| ORF Vector | Template DNA | PC128327 | View Product |
Mouse Mef2c Gene Overview
| Gene Name | myocyte enhancer factor 2C |
|---|---|
| Gene Symbol | Mef2c |
| Synonyms | Mef2,5430401D19Rik,9930028G15Rik |
| NCBI ID | 17260 |
| Ensembl ID | ENSMUSG00000005583 |
| Uniprot ID | Q8CFN5 |
| Gene Type | Protein coding |
Gene Summary
Enables several functions, including DNA-binding transcription activator activity, RNA polymerase II-specific; HMG box domain binding activity; and histone deacetylase binding activity. Involved in several processes, including heart development; modulation of chemical synaptic transmission; and positive regulation of cell differentiation. Acts upstream of with a negative effect on AMPA selective glutamate receptor signaling pathway and NMDA selective glutamate receptor signaling pathway. Acts upstream of or within several processes, including cardiac muscle hypertrophy in response to stress; circulatory system development; and skeletal system development. Located in nucleus. Is expressed in several structures, including alimentary system; central nervous system; heart and pericardium; limb; and urinary system. Human ortholog(s) of this gene implicated in neurodevelopmental disorder with hypotonia, stereotypic hand movements, and impaired language. Orthologous to human MEF2C (myocyte enhancer factor 2C). [provided by Alliance of Genome Resources, Apr 2025]
Mouse Mef2c Related Products
| Product Type | Key Applications | Cat. No. | Product |
|---|---|---|---|
| Lentiviral Vector & Virus | Stable overexpression | LC428327 | View Product |
| Stable overexpression | LC528327 | View Product | |
| AAV Vector & Virus | Long-term expression | VC428327 | View Product |
| Long-term expression | VC528327 | View Product | |
| Adenovirus | Transient expression | A428327 | View Product |
| Transient expression | A528327 | View Product | |
| ORF Vector | Template DNA | PC428327 | View Product |
| Template DNA | PC528327 | View Product |
Rat Mef2c Gene Overview
| Gene Name | myocyte enhancer factor 2C |
|---|---|
| Gene Symbol | Mef2c |
| Synonyms | RGD1563119 |
| NCBI ID | 499497 |
| Ensembl ID | ENSRNOG00000033134 |
| Uniprot ID | A0A096MJY4 |
| Gene Type | Protein coding |
Gene Summary
Enables DNA binding activity and DNA-binding transcription factor activity, RNA polymerase II-specific. Involved in several processes, including dentate gyrus development; response to ischemia; and transdifferentiation. Located in cytosol; nucleus; and sarcomere. Used to study myocardial infarction. Biomarker of status epilepticus. Human ortholog(s) of this gene implicated in neurodevelopmental disorder with hypotonia, stereotypic hand movements, and impaired language. Orthologous to human MEF2C (myocyte enhancer factor 2C). [provided by Alliance of Genome Resources, Jul 2025]
Rat Mef2c Related Products
| Product Type | Key Applications | Cat. No. | Product |
|---|
Accelerate Discovery with Research-Ready Constructs
| Why Researchers Choose abm | Workflow Benefits |
|---|---|
| Gene-Specific Constructs | Eliminate time-consuming cloning and accelerate project timelines |
| Available as Plasmid DNA or Packaged Virus | Choose delivery format that best fits your experiment |
| Validated Sequence Design | Ensure reliable, reproducible experimental performance |
| Available in Multiple Species Options | Simplify cross-species and translational research studies |
| Flexible Customization Services | Tailor constructs with different promoters, tags, markers and other modifications |
| Expert Technical Support | Get guidance from gene delivery specialists |
Product Overview & Key Features
| System | Applications | Key Features |
|---|---|---|
| CRISPR Knockout Vectors & Viruses | Targeted gene disruption & functional knockout studies | •Pre-designed validated sgRNAs •Available in All-in-One Cas9 + sgRNA or sgRNA-only formats •Available as lentivirus, AAV and non-viral •Ideal for stable genome editing |
| Lentiviral Expression Vectors & Particles | Stable gene overexpression or delivery into difficult-to-transfect cells | •Long-term expression through genomic integration •Highly efficient in dividing and non-dividing cells •Ideal for stable cell line generation |
| AAV Vectors & Packaged Virus | In vivo delivery & transient expression with low immunogenicity | •Multiple serotypes available for tissue targeting •Excellent for animal studies and sensitive primary cells •Episomal expression with strong safety profile |
| Adenovirus | High-efficiency transient expression | •Rapid, robust gene expression •Large cargo capacity •Ideal for primary cells and strong short-term expression studies |
| ORF Vector | Template for coding sequence | •Ready-to-use full-length coding sequences •Low cost and convenient alternative to gene synthesis |
| siRNA Knockdown Tools | Temporary gene silencing & pathway validation | •Robust gene knockdown •Ideal for target validation and preliminary functional screening •Available as Lentivirus, AAV or synthetic dsRNA oligos |