MIF Expression Vectors, Lentivirus & CRISPR Knockout Vectors
Enhance your research with ready-to-use MIF-specific vectors and viral particles designed for reliable MIF overexpression, knockout, and silencing across a wide range of experimental systems. abm offers a complete portfolio of validated molecular tools – including MIF CRISPR knockout vectors, lentiviral particles, AAV vectors, adenovirus, ORF clones, and siRNA constructs for both in vitro and in vivo applications.
Human MIF Gene Overview
| Gene Name | macrophage migration inhibitory factor |
|---|---|
| Gene Symbol | MIF |
| Synonyms | GIF,GLIF,MMIF |
| NCBI ID | 4282 |
| Ensembl ID | ENSG00000240972 |
| Uniprot ID | P14174 |
| Gene Type | Protein coding |
Gene Summary
This gene encodes a lymphokine involved in cell-mediated immunity, immunoregulation, and inflammation. It plays a role in the regulation of macrophage function in host defense through the suppression of anti-inflammatory effects of glucocorticoids. This lymphokine and the JAB1 protein form a complex in the cytosol near the peripheral plasma membrane, which may indicate an additional role in integrin signaling pathways. [provided by RefSeq, Jul 2008]
Human MIF Related Products
| Product Type | Key Applications | Cat. No. | Product |
|---|---|---|---|
| Lentiviral Vector & Virus | Stable overexpression | LC128596 | View Product |
| AAV Vector & Virus | Long-term expression | VC128596 | View Product |
| Adenovirus | Transient expression | A128596 | View Product |
| CRISPR KO Tools | Gene knockout (Lentiviral) | LG128596 | View Product |
| Gene knockout (non-viral) | PG128596 | View Product | |
| Gene knockout (AAV) | VG128596 | View Product | |
| CRISPR Activation | Gene activation | LA128596 | View Product |
| siRNA Tools | Gene knockdown (Lentiviral) | LS128596 | View Product |
| Gene knockdown (AAV) | VS128596 | View Product | |
| ORF Vector | Template DNA | PC128596 | View Product |
Mouse Mif Gene Overview
| Gene Name | macrophage migration inhibitory factor (glycosylation-inhibiting factor) |
|---|---|
| Gene Symbol | Mif |
| Synonyms | GIF,DER6,Glif |
| NCBI ID | 17319 |
| Ensembl ID | ENSMUSG00000033307 |
| Uniprot ID | P34884 |
| Gene Type | Protein coding |
Gene Summary
Enables cytokine activity; phenylpyruvate tautomerase activity; and protease binding activity. Involved in several processes, including positive regulation of cytokine production; positive regulation of icosanoid secretion; and regulation of signal transduction. Acts upstream of or within DNA damage response, signal transduction by p53 class mediator; cellular senescence; and regulation of cell population proliferation. Located in extracellular space. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; respiratory system; and sensory organ. Human ortholog(s) of this gene implicated in allergic disease; asthma; cystic fibrosis; lung disease (multiple); and obesity. Orthologous to human MIF (macrophage migration inhibitory factor). [provided by Alliance of Genome Resources, Jul 2025]
Mouse Mif Related Products
| Product Type | Key Applications | Cat. No. | Product |
|---|---|---|---|
| Lentiviral Vector & Virus | Stable overexpression | LC428596 | View Product |
| AAV Vector & Virus | Long-term expression | VC428596 | View Product |
| Adenovirus | Transient expression | A428596 | View Product |
| CRISPR KO Tools | Gene knockout (Lentiviral) | LG428596 | View Product |
| Gene knockout (non-viral) | PG428596 | View Product | |
| Gene knockout (AAV) | VG428596 | View Product | |
| CRISPR Activation | Gene activation | LA428596 | View Product |
| siRNA Tools | Gene knockdown (Lentiviral) | LS428596 | View Product |
| Gene knockdown (AAV) | VS428596 | View Product | |
| ORF Vector | Template DNA | PC428596 | View Product |
Rat Mif Gene Overview
| Gene Name | macrophage migration inhibitory factor |
|---|---|
| Gene Symbol | Mif |
| Synonyms | |
| NCBI ID | 81683 |
| Ensembl ID | |
| Uniprot ID | P30904 |
| Gene Type | Protein coding |
Gene Summary
Predicted to enable several functions, including identical protein binding activity; intramolecular oxidoreductase activity; and receptor ligand activity. Involved in several processes, including brain renin-angiotensin system; positive regulation of glycolytic process; and positive regulation of transport. Located in extracellular space. Used to study several diseases, including acute necrotizing pancreatitis; cardiomyopathy (multiple); lung disease (multiple); retinitis; and toxic shock syndrome. Biomarker of borna disease; cystitis; kidney disease; myocardial infarction; and type 2 diabetes mellitus. Human ortholog(s) of this gene implicated in allergic disease; asthma; cystic fibrosis; lung disease (multiple); and obesity. Orthologous to human MIF (macrophage migration inhibitory factor). [provided by Alliance of Genome Resources, Jul 2025]
Rat Mif Related Products
| Product Type | Key Applications | Cat. No. | Product |
|---|---|---|---|
| Lentiviral Vector & Virus | Stable overexpression | LC628596 | View Product |
| AAV Vector & Virus | Long-term expression | VC628596 | View Product |
| Adenovirus | Transient expression | A628596 | View Product |
| CRISPR KO Tools | Gene knockout (Lentiviral) | LG628596 | View Product |
| Gene knockout (non-viral) | PG628596 | View Product | |
| Gene knockout (AAV) | VG628596 | View Product | |
| CRISPR Activation | Gene activation | LA628596 | View Product |
| siRNA Tools | Gene knockdown (Lentiviral) | LS628596 | View Product |
| Gene knockdown (AAV) | VS628596 | View Product | |
| ORF Vector | Template DNA | PC628596 | View Product |
Accelerate Discovery with Research-Ready Constructs
| Why Researchers Choose abm | Workflow Benefits |
|---|---|
| Gene-Specific Constructs | Eliminate time-consuming cloning and accelerate project timelines |
| Available as Plasmid DNA or Packaged Virus | Choose delivery format that best fits your experiment |
| Validated Sequence Design | Ensure reliable, reproducible experimental performance |
| Available in Multiple Species Options | Simplify cross-species and translational research studies |
| Flexible Customization Services | Tailor constructs with different promoters, tags, markers and other modifications |
| Expert Technical Support | Get guidance from gene delivery specialists |
Product Overview & Key Features
| System | Applications | Key Features |
|---|---|---|
| CRISPR Knockout Vectors & Viruses | Targeted gene disruption & functional knockout studies | •Pre-designed validated sgRNAs •Available in All-in-One Cas9 + sgRNA or sgRNA-only formats •Available as lentivirus, AAV and non-viral •Ideal for stable genome editing |
| Lentiviral Expression Vectors & Particles | Stable gene overexpression or delivery into difficult-to-transfect cells | •Long-term expression through genomic integration •Highly efficient in dividing and non-dividing cells •Ideal for stable cell line generation |
| AAV Vectors & Packaged Virus | In vivo delivery & transient expression with low immunogenicity | •Multiple serotypes available for tissue targeting •Excellent for animal studies and sensitive primary cells •Episomal expression with strong safety profile |
| Adenovirus | High-efficiency transient expression | •Rapid, robust gene expression •Large cargo capacity •Ideal for primary cells and strong short-term expression studies |
| ORF Vector | Template for coding sequence | •Ready-to-use full-length coding sequences •Low cost and convenient alternative to gene synthesis |
| siRNA Knockdown Tools | Temporary gene silencing & pathway validation | •Robust gene knockdown •Ideal for target validation and preliminary functional screening •Available as Lentivirus, AAV or synthetic dsRNA oligos |