MS4A1 Expression Vectors, Lentivirus & CRISPR Knockout Vectors
Enhance your research with ready-to-use MS4A1-specific vectors and viral particles designed for reliable MS4A1 overexpression, knockout, and silencing across a wide range of experimental systems. abm offers a complete portfolio of validated molecular tools – including MS4A1 CRISPR knockout vectors, lentiviral particles, AAV vectors, adenovirus, ORF clones, and siRNA constructs for both in vitro and in vivo applications.
Human MS4A1 Gene Overview
| Gene Name | membrane spanning 4-domains A1 |
|---|---|
| Gene Symbol | MS4A1 |
| Synonyms | B1,S7,Bp35,CD20,FMC7,CVID5,LEU-16 |
| NCBI ID | 931 |
| Ensembl ID | ENSG00000156738 |
| Uniprot ID | P11836 |
| Gene Type | Protein coding |
Gene Summary
This gene encodes a member of the membrane-spanning 4A gene family. Members of this nascent protein family are characterized by common structural features and similar intron/exon splice boundaries and display unique expression patterns among hematopoietic cells and nonlymphoid tissues. This gene encodes a B-lymphocyte surface molecule which plays a role in the development and differentiation of B-cells into plasma cells. This family member is localized to 11q12, among a cluster of family members. Alternative splicing of this gene results in two transcript variants which encode the same protein. [provided by RefSeq, Jul 2008]
Human MS4A1 Related Products
| Product Type | Key Applications | Cat. No. | Product |
|---|---|---|---|
| Lentiviral Vector & Virus | Stable overexpression | LC130697 | View Product |
| AAV Vector & Virus | Long-term expression | VC130697 | View Product |
| Adenovirus | Transient expression | A130697 | View Product |
| CRISPR KO Tools | Gene knockout (Lentiviral) | LG130697 | View Product |
| Gene knockout (non-viral) | PG130697 | View Product | |
| Gene knockout (AAV) | VG130697 | View Product | |
| CRISPR Activation | Gene activation | LA130697 | View Product |
| siRNA Tools | Gene knockdown (Lentiviral) | LS130697 | View Product |
| Gene knockdown (AAV) | VS130697 | View Product | |
| ORF Vector | Template DNA | PC130697 | View Product |
Mouse Ms4a1 Gene Overview
| Gene Name | membrane-spanning 4-domains, subfamily A, member 1 |
|---|---|
| Gene Symbol | Ms4a1 |
| Synonyms | Cd20,Ly-44,Ms4a2 |
| NCBI ID | 12482 |
| Ensembl ID | ENSMUSG00000024673 |
| Uniprot ID | P19437 |
| Gene Type | Protein coding |
Gene Summary
Predicted to enable epidermal growth factor receptor binding activity; identical protein binding activity; and immunoglobulin binding activity. Involved in positive regulation of calcium ion import across plasma membrane. Acts upstream of or within response to bacterium. Located in external side of plasma membrane. Is expressed in several structures, including alimentary system; brain; genitourinary system; hemolymphoid system gland; and liver and biliary system. Human ortholog(s) of this gene implicated in common variable immunodeficiency 5. Orthologous to human MS4A1 (membrane spanning 4-domains A1). [provided by Alliance of Genome Resources, Jul 2025]
Mouse Ms4a1 Related Products
| Product Type | Key Applications | Cat. No. | Product |
|---|---|---|---|
| Lentiviral Vector & Virus | Stable overexpression | LC430697 | View Product |
| AAV Vector & Virus | Long-term expression | VC430697 | View Product |
| Adenovirus | Transient expression | A430697 | View Product |
| CRISPR KO Tools | Gene knockout (Lentiviral) | LG430697 | View Product |
| Gene knockout (non-viral) | PG430697 | View Product | |
| Gene knockout (AAV) | VG430697 | View Product | |
| CRISPR Activation | Gene activation | LA430697 | View Product |
| siRNA Tools | Gene knockdown (Lentiviral) | LS430697 | View Product |
| Gene knockdown (AAV) | VS430697 | View Product | |
| ORF Vector | Template DNA | PC430697 | View Product |
Rat Ms4a1 Gene Overview
| Gene Name | membrane spanning 4-domains A1 |
|---|---|
| Gene Symbol | Ms4a1 |
| Synonyms | Cd20 |
| NCBI ID | 309217 |
| Ensembl ID | ENSRNOG00000020945 |
| Uniprot ID | |
| Gene Type | Protein coding |
Gene Summary
Enables epidermal growth factor receptor binding activity. Predicted to be involved in several processes, including B cell receptor signaling pathway; calcium ion transport; and positive regulation of calcium ion import across plasma membrane. Predicted to act upstream of or within response to bacterium. Predicted to be located in cell surface; nucleoplasm; and plasma membrane raft. Predicted to be active in external side of plasma membrane. Biomarker of glomerulonephritis. Human ortholog(s) of this gene implicated in common variable immunodeficiency 5. Orthologous to human MS4A1 (membrane spanning 4-domains A1). [provided by Alliance of Genome Resources, Jul 2025]
Rat Ms4a1 Related Products
| Product Type | Key Applications | Cat. No. | Product |
|---|---|---|---|
| Lentiviral Vector & Virus | Stable overexpression | LC630697 | View Product |
| CRISPR KO Tools | Gene knockout (Lentiviral) | LG630697 | View Product |
| Gene knockout (non-viral) | PG630697 | View Product | |
| Gene knockout (AAV) | VG630697 | View Product | |
| CRISPR Activation | Gene activation | LA630697 | View Product |
| siRNA Tools | Gene knockdown (Lentiviral) | LS630697 | View Product |
| Gene knockdown (AAV) | VS630697 | View Product | |
| ORF Vector | Template DNA | PC630697 | View Product |
Accelerate Discovery with Research-Ready Constructs
| Why Researchers Choose abm | Workflow Benefits |
|---|---|
| Gene-Specific Constructs | Eliminate time-consuming cloning and accelerate project timelines |
| Available as Plasmid DNA or Packaged Virus | Choose delivery format that best fits your experiment |
| Validated Sequence Design | Ensure reliable, reproducible experimental performance |
| Available in Multiple Species Options | Simplify cross-species and translational research studies |
| Flexible Customization Services | Tailor constructs with different promoters, tags, markers and other modifications |
| Expert Technical Support | Get guidance from gene delivery specialists |
Product Overview & Key Features
| System | Applications | Key Features |
|---|---|---|
| CRISPR Knockout Vectors & Viruses | Targeted gene disruption & functional knockout studies | •Pre-designed validated sgRNAs •Available in All-in-One Cas9 + sgRNA or sgRNA-only formats •Available as lentivirus, AAV and non-viral •Ideal for stable genome editing |
| Lentiviral Expression Vectors & Particles | Stable gene overexpression or delivery into difficult-to-transfect cells | •Long-term expression through genomic integration •Highly efficient in dividing and non-dividing cells •Ideal for stable cell line generation |
| AAV Vectors & Packaged Virus | In vivo delivery & transient expression with low immunogenicity | •Multiple serotypes available for tissue targeting •Excellent for animal studies and sensitive primary cells •Episomal expression with strong safety profile |
| Adenovirus | High-efficiency transient expression | •Rapid, robust gene expression •Large cargo capacity •Ideal for primary cells and strong short-term expression studies |
| ORF Vector | Template for coding sequence | •Ready-to-use full-length coding sequences •Low cost and convenient alternative to gene synthesis |
| siRNA Knockdown Tools | Temporary gene silencing & pathway validation | •Robust gene knockdown •Ideal for target validation and preliminary functional screening •Available as Lentivirus, AAV or synthetic dsRNA oligos |