MSTN Expression Vectors, Lentivirus & CRISPR Knockout Vectors
Enhance your research with ready-to-use MSTN-specific vectors and viral particles designed for reliable MSTN overexpression, knockout, and silencing across a wide range of experimental systems. abm offers a complete portfolio of validated molecular tools – including MSTN CRISPR knockout vectors, lentiviral particles, AAV vectors, adenovirus, ORF clones, and siRNA constructs for both in vitro and in vivo applications.
Human MSTN Gene Overview
| Gene Name | myostatin |
|---|---|
| Gene Symbol | MSTN |
| Synonyms | GDF8,MSLHP |
| NCBI ID | 2660 |
| Ensembl ID | ENSG00000138379 |
| Uniprot ID | O14793 |
| Gene Type | Protein coding |
Gene Summary
This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein negatively regulates skeletal muscle cell proliferation and differentiation. Mutations in this gene are associated with increased skeletal muscle mass in humans and other mammals. [provided by RefSeq, Jul 2016]
Human MSTN Related Products
| Product Type | Key Applications | Cat. No. | Product |
|---|---|---|---|
| Lentiviral Vector & Virus | Stable overexpression | LC130768 | View Product |
| AAV Vector & Virus | Long-term expression | VC130768 | View Product |
| Adenovirus | Transient expression | A130768 | View Product |
| CRISPR KO Tools | Gene knockout (Lentiviral) | LG130768 | View Product |
| Gene knockout (non-viral) | PG130768 | View Product | |
| Gene knockout (AAV) | VG130768 | View Product | |
| CRISPR Activation | Gene activation | LA130768 | View Product |
| siRNA Tools | Gene knockdown (Lentiviral) | LS130768 | View Product |
| Gene knockdown (AAV) | VS130768 | View Product | |
| ORF Vector | Template DNA | PC130768 | View Product |
Mouse Mstn Gene Overview
| Gene Name | myostatin |
|---|---|
| Gene Symbol | Mstn |
| Synonyms | Cmpt,Gdf8 |
| NCBI ID | 17700 |
| Ensembl ID | ENSMUSG00000026100 |
| Uniprot ID | O08689 |
| Gene Type | Protein coding |
Gene Summary
This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein negatively regulates skeletal muscle cell proliferation and differentiation. Homozygous knockout mice for this gene exhibit increased muscle mass and bone density, and reduced adiposity. [provided by RefSeq, Jul 2016]
Mouse Mstn Related Products
| Product Type | Key Applications | Cat. No. | Product |
|---|---|---|---|
| Lentiviral Vector & Virus | Stable overexpression | LC430768 | View Product |
| AAV Vector & Virus | Long-term expression | VC430768 | View Product |
| Adenovirus | Transient expression | A430768 | View Product |
| CRISPR KO Tools | Gene knockout (Lentiviral) | LG430768 | View Product |
| Gene knockout (non-viral) | PG430768 | View Product | |
| Gene knockout (AAV) | VG430768 | View Product | |
| CRISPR Activation | Gene activation | LA430768 | View Product |
| siRNA Tools | Gene knockdown (Lentiviral) | LS430768 | View Product |
| Gene knockdown (AAV) | VS430768 | View Product | |
| ORF Vector | Template DNA | PC430768 | View Product |
Rat Mstn Gene Overview
| Gene Name | myostatin |
|---|---|
| Gene Symbol | Mstn |
| Synonyms | Gdf8 |
| NCBI ID | 29152 |
| Ensembl ID | ENSRNOG00000021294 |
| Uniprot ID | O35312 |
| Gene Type | Protein coding |
Gene Summary
This gene encodes a member of the TGF-beta (transforming growth factor-beta) family of proteins. The encoded preproprotein is proteolytically processed to generate an N-terminal propeptide and a C-terminal subunit. The C-terminal subunits form the mature homodimer, which negatively regulates skeletal muscle cell proliferation and differentiation. Mutations in this gene are associated with increased skeletal muscle mass in humans and other mammals. [provided by RefSeq, Jun 2016]
Rat Mstn Related Products
| Product Type | Key Applications | Cat. No. | Product |
|---|---|---|---|
| Lentiviral Vector & Virus | Stable overexpression | LC630768 | View Product |
| AAV Vector & Virus | Long-term expression | VC630768 | View Product |
| Adenovirus | Transient expression | A630768 | View Product |
| CRISPR KO Tools | Gene knockout (Lentiviral) | LG630768 | View Product |
| Gene knockout (non-viral) | PG630768 | View Product | |
| Gene knockout (AAV) | VG630768 | View Product | |
| CRISPR Activation | Gene activation | LA630768 | View Product |
| siRNA Tools | Gene knockdown (Lentiviral) | LS630768 | View Product |
| Gene knockdown (AAV) | VS630768 | View Product | |
| ORF Vector | Template DNA | PC630768 | View Product |
Accelerate Discovery with Research-Ready Constructs
| Why Researchers Choose abm | Workflow Benefits |
|---|---|
| Gene-Specific Constructs | Eliminate time-consuming cloning and accelerate project timelines |
| Available as Plasmid DNA or Packaged Virus | Choose delivery format that best fits your experiment |
| Validated Sequence Design | Ensure reliable, reproducible experimental performance |
| Available in Multiple Species Options | Simplify cross-species and translational research studies |
| Flexible Customization Services | Tailor constructs with different promoters, tags, markers and other modifications |
| Expert Technical Support | Get guidance from gene delivery specialists |
Product Overview & Key Features
| System | Applications | Key Features |
|---|---|---|
| CRISPR Knockout Vectors & Viruses | Targeted gene disruption & functional knockout studies | •Pre-designed validated sgRNAs •Available in All-in-One Cas9 + sgRNA or sgRNA-only formats •Available as lentivirus, AAV and non-viral •Ideal for stable genome editing |
| Lentiviral Expression Vectors & Particles | Stable gene overexpression or delivery into difficult-to-transfect cells | •Long-term expression through genomic integration •Highly efficient in dividing and non-dividing cells •Ideal for stable cell line generation |
| AAV Vectors & Packaged Virus | In vivo delivery & transient expression with low immunogenicity | •Multiple serotypes available for tissue targeting •Excellent for animal studies and sensitive primary cells •Episomal expression with strong safety profile |
| Adenovirus | High-efficiency transient expression | •Rapid, robust gene expression •Large cargo capacity •Ideal for primary cells and strong short-term expression studies |
| ORF Vector | Template for coding sequence | •Ready-to-use full-length coding sequences •Low cost and convenient alternative to gene synthesis |
| siRNA Knockdown Tools | Temporary gene silencing & pathway validation | •Robust gene knockdown •Ideal for target validation and preliminary functional screening •Available as Lentivirus, AAV or synthetic dsRNA oligos |