MUC1 Expression Vectors, Lentivirus & CRISPR Knockout Vectors
Enhance your research with ready-to-use MUC1-specific vectors and viral particles designed for reliable MUC1 overexpression, knockout, and silencing across a wide range of experimental systems. abm offers a complete portfolio of validated molecular tools – including MUC1 CRISPR knockout vectors, lentiviral particles, AAV vectors, adenovirus, ORF clones, and siRNA constructs for both in vitro and in vivo applications.
Human MUC1 Gene Overview
| Gene Name | mucin 1, cell surface associated |
|---|---|
| Gene Symbol | MUC1 |
| Synonyms | EMA,MCD,PEM,PUM,KL-6,MAM6,MCKD,PEMT,CD227,H23AG,MCKD1,MUC-1,ADMCKD,ADTKD2,Ca15-3,ADMCKD1,CA 15-3,MUC-1/X,MUC1/ZD,MUC-1/SEC |
| NCBI ID | 4582 |
| Ensembl ID | ENSG00000185499 |
| Uniprot ID | P15941 |
| Gene Type | Protein coding |
Gene Summary
This gene encodes a membrane-bound protein that is a member of the mucin family. Mucins are O-glycosylated proteins that play an essential role in forming protective mucous barriers on epithelial surfaces. These proteins also play a role in intracellular signaling. This protein is expressed on the apical surface of epithelial cells that line the mucosal surfaces of many different tissues including lung, breast stomach and pancreas. This protein is proteolytically cleaved into alpha and beta subunits that form a heterodimeric complex. The N-terminal alpha subunit functions in cell-adhesion and the C-terminal beta subunit is involved in cell signaling. Overexpression, aberrant intracellular localization, and changes in glycosylation of this protein have been associated with carcinomas. This gene is known to contain a highly polymorphic variable number tandem repeats (VNTR) domain. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Feb 2011]
Human MUC1 Related Products
| Product Type | Key Applications | Cat. No. | Product |
|---|---|---|---|
| Lentiviral Vector & Virus | Stable overexpression | LC122524 | View Product |
| Stable overexpression | LC131126 | View Product | |
| AAV Vector & Virus | Long-term expression | VC122524 | View Product |
| Long-term expression | VC131126 | View Product | |
| Adenovirus | Transient expression | A122524 | View Product |
| Transient expression | A131126 | View Product | |
| CRISPR KO Tools | Gene knockout (Lentiviral) | LG131126 | View Product |
| Gene knockout (non-viral) | PG131126 | View Product | |
| Gene knockout (AAV) | VG131126 | View Product | |
| CRISPR Activation | Gene activation | LA131126 | View Product |
| siRNA Tools | Gene knockdown (Lentiviral) | LS131126 | View Product |
| Gene knockdown (AAV) | VS131126 | View Product | |
| ORF Vector | Template DNA | PC122524 | View Product |
| Template DNA | PC131126 | View Product |
Mouse Muc1 Gene Overview
| Gene Name | mucin 1, transmembrane |
|---|---|
| Gene Symbol | Muc1 |
| Synonyms | EMA,CD227,Muc-1 |
| NCBI ID | 17829 |
| Ensembl ID | ENSMUSG00000042784 |
| Uniprot ID | Q02496 |
| Gene Type | Protein coding |
Gene Summary
Predicted to enable RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; p53 binding activity; and transcription coregulator activity. Predicted to be involved in several processes, including DNA damage response, signal transduction by p53 class mediator; negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator; and regulation of DNA-templated transcription. Located in apical plasma membrane and cell surface. Is expressed in several structures, including alimentary system; brain; exocrine system; genitourinary system; and respiratory system. Human ortholog(s) of this gene implicated in several diseases, including allergic rhinitis; autosomal dominant tubulointerstitial kidney disease; biliary tract benign neoplasm; dry eye syndrome; and pancreatic cancer (multiple). Orthologous to human MUC1 (mucin 1, cell surface associated). [provided by Alliance of Genome Resources, Apr 2025]
Mouse Muc1 Related Products
| Product Type | Key Applications | Cat. No. | Product |
|---|---|---|---|
| Lentiviral Vector & Virus | Stable overexpression | LC431126 | View Product |
| AAV Vector & Virus | Long-term expression | VC431126 | View Product |
| Adenovirus | Transient expression | A431126 | View Product |
| CRISPR KO Tools | Gene knockout (Lentiviral) | LG431126 | View Product |
| Gene knockout (non-viral) | PG431126 | View Product | |
| Gene knockout (AAV) | VG431126 | View Product | |
| CRISPR Activation | Gene activation | LA431126 | View Product |
| siRNA Tools | Gene knockdown (Lentiviral) | LS431126 | View Product |
| Gene knockdown (AAV) | VS431126 | View Product | |
| ORF Vector | Template DNA | PC431126 | View Product |
Rat Muc1 Gene Overview
| Gene Name | mucin 1, cell surface associated |
|---|---|
| Gene Symbol | Muc1 |
| Synonyms | |
| NCBI ID | 24571 |
| Ensembl ID | ENSRNOG00000020539 |
| Uniprot ID | |
| Gene Type | Protein coding |
Gene Summary
Predicted to enable RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; p53 binding activity; and transcription coregulator activity. Involved in several processes, including cellular response to retinoic acid; female pregnancy; and response to hypoxia. Located in apical plasma membrane. Used to study allergic rhinitis. Biomarker of allergic rhinitis; cholangiocarcinoma; and otitis media. Human ortholog(s) of this gene implicated in several diseases, including autosomal dominant tubulointerstitial kidney disease; biliary tract benign neoplasm; dry eye syndrome; mucinous adenocarcinoma; and pancreatic cancer (multiple). Orthologous to human MUC1 (mucin 1, cell surface associated). [provided by Alliance of Genome Resources, Apr 2025]
Rat Muc1 Related Products
| Product Type | Key Applications | Cat. No. | Product |
|---|---|---|---|
| Lentiviral Vector & Virus | Stable overexpression | LC631126 | View Product |
| CRISPR KO Tools | Gene knockout (Lentiviral) | LG631126 | View Product |
| Gene knockout (non-viral) | PG631126 | View Product | |
| Gene knockout (AAV) | VG631126 | View Product | |
| CRISPR Activation | Gene activation | LA631126 | View Product |
| siRNA Tools | Gene knockdown (Lentiviral) | LS631126 | View Product |
| Gene knockdown (AAV) | VS631126 | View Product | |
| ORF Vector | Template DNA | PC631126 | View Product |
Accelerate Discovery with Research-Ready Constructs
| Why Researchers Choose abm | Workflow Benefits |
|---|---|
| Gene-Specific Constructs | Eliminate time-consuming cloning and accelerate project timelines |
| Available as Plasmid DNA or Packaged Virus | Choose delivery format that best fits your experiment |
| Validated Sequence Design | Ensure reliable, reproducible experimental performance |
| Available in Multiple Species Options | Simplify cross-species and translational research studies |
| Flexible Customization Services | Tailor constructs with different promoters, tags, markers and other modifications |
| Expert Technical Support | Get guidance from gene delivery specialists |
Product Overview & Key Features
| System | Applications | Key Features |
|---|---|---|
| CRISPR Knockout Vectors & Viruses | Targeted gene disruption & functional knockout studies | •Pre-designed validated sgRNAs •Available in All-in-One Cas9 + sgRNA or sgRNA-only formats •Available as lentivirus, AAV and non-viral •Ideal for stable genome editing |
| Lentiviral Expression Vectors & Particles | Stable gene overexpression or delivery into difficult-to-transfect cells | •Long-term expression through genomic integration •Highly efficient in dividing and non-dividing cells •Ideal for stable cell line generation |
| AAV Vectors & Packaged Virus | In vivo delivery & transient expression with low immunogenicity | •Multiple serotypes available for tissue targeting •Excellent for animal studies and sensitive primary cells •Episomal expression with strong safety profile |
| Adenovirus | High-efficiency transient expression | •Rapid, robust gene expression •Large cargo capacity •Ideal for primary cells and strong short-term expression studies |
| ORF Vector | Template for coding sequence | •Ready-to-use full-length coding sequences •Low cost and convenient alternative to gene synthesis |
| siRNA Knockdown Tools | Temporary gene silencing & pathway validation | •Robust gene knockdown •Ideal for target validation and preliminary functional screening •Available as Lentivirus, AAV or synthetic dsRNA oligos |