NAMPT Expression Vectors, Lentivirus & CRISPR Knockout Vectors
Enhance your research with ready-to-use NAMPT-specific vectors and viral particles designed for reliable NAMPT overexpression, knockout, and silencing across a wide range of experimental systems. abm offers a complete portfolio of validated molecular tools – including NAMPT CRISPR knockout vectors, lentiviral particles, AAV vectors, adenovirus, ORF clones, and siRNA constructs for both in vitro and in vivo applications.
Human NAMPT Gene Overview
| Gene Name | nicotinamide phosphoribosyltransferase |
|---|---|
| Gene Symbol | NAMPT |
| Synonyms | VF,PBEF,PBEF1,VISFATIN,1110035O14Rik |
| NCBI ID | 10135 |
| Ensembl ID | ENSG00000105835 |
| Uniprot ID | P43490 |
| Gene Type | Protein coding |
Gene Summary
This gene encodes a protein that catalyzes the condensation of nicotinamide with 5-phosphoribosyl-1-pyrophosphate to yield nicotinamide mononucleotide, one step in the biosynthesis of nicotinamide adenine dinucleotide. The protein belongs to the nicotinic acid phosphoribosyltransferase (NAPRTase) family and is thought to be involved in many important biological processes, including metabolism, stress response and aging. This gene has a pseudogene on chromosome 10. [provided by RefSeq, Feb 2011]
Human NAMPT Related Products
| Product Type | Key Applications | Cat. No. | Product |
|---|---|---|---|
| Lentiviral Vector & Virus | Stable overexpression | LC131414 | View Product |
| AAV Vector & Virus | Long-term expression | VC131414 | View Product |
| Adenovirus | Transient expression | A131414 | View Product |
| CRISPR KO Tools | Gene knockout (Lentiviral) | LG131414 | View Product |
| Gene knockout (non-viral) | PG131414 | View Product | |
| Gene knockout (AAV) | VG131414 | View Product | |
| CRISPR Activation | Gene activation | LA131414 | View Product |
| siRNA Tools | Gene knockdown (Lentiviral) | LS131414 | View Product |
| Gene knockdown (AAV) | VS131414 | View Product | |
| ORF Vector | Template DNA | PC131414 | View Product |
Mouse Nampt Gene Overview
| Gene Name | nicotinamide phosphoribosyltransferase |
|---|---|
| Gene Symbol | Nampt |
| Synonyms | Pbef,Pbef1,Visfatin,NAmPRTase,1110035O14Rik |
| NCBI ID | 59027 |
| Ensembl ID | ENSMUSG00000020572 |
| Uniprot ID | Q99KQ4 |
| Gene Type | Protein coding |
Gene Summary
Enables identical protein binding activity and nicotinamide phosphoribosyltransferase activity. Involved in circadian regulation of gene expression; nicotinamide metabolic process; and nicotinamide nucleotide biosynthetic process. Acts upstream of or within NAD biosynthetic process. Located in cytoplasm. Is active in cytosol and mitochondrial matrix. Is expressed in several structures, including alimentary system; genitourinary system; integumental system; nervous system; and sensory organ. Human ortholog(s) of this gene implicated in transient cerebral ischemia. Orthologous to human NAMPT (nicotinamide phosphoribosyltransferase). [provided by Alliance of Genome Resources, Apr 2025]
Mouse Nampt Related Products
| Product Type | Key Applications | Cat. No. | Product |
|---|---|---|---|
| Lentiviral Vector & Virus | Stable overexpression | LC431414 | View Product |
| AAV Vector & Virus | Long-term expression | VC431414 | View Product |
| Adenovirus | Transient expression | A431414 | View Product |
| CRISPR KO Tools | Gene knockout (Lentiviral) | LG431414 | View Product |
| Gene knockout (non-viral) | PG431414 | View Product | |
| Gene knockout (AAV) | VG431414 | View Product | |
| CRISPR Activation | Gene activation | LA431414 | View Product |
| siRNA Tools | Gene knockdown (Lentiviral) | LS431414 | View Product |
| Gene knockdown (AAV) | VS431414 | View Product | |
| ORF Vector | Template DNA | PC431414 | View Product |
Rat Nampt Gene Overview
| Gene Name | nicotinamide phosphoribosyltransferase |
|---|---|
| Gene Symbol | Nampt |
| Synonyms | Pbef,Pbef1 |
| NCBI ID | 297508 |
| Ensembl ID | ENSRNOG00000009754 |
| Uniprot ID | Q80Z29 |
| Gene Type | Protein coding |
Gene Summary
Enables several functions, including cytokine activity; identical protein binding activity; and nicotinamide phosphoribosyltransferase activity. Involved in several processes, including cellular response to amyloid-beta; microglial cell activation; and negative regulation of cellular senescence. Predicted to be located in cell junction; cytoplasm; and nuclear speck. Used to study middle cerebral artery infarction and transient cerebral ischemia. Biomarker of kidney failure; metabolic dysfunction-associated steatotic liver disease; periodontitis; and pulmonary hypertension. Human ortholog(s) of this gene implicated in transient cerebral ischemia. Orthologous to human NAMPT (nicotinamide phosphoribosyltransferase). [provided by Alliance of Genome Resources, Apr 2025]
Rat Nampt Related Products
| Product Type | Key Applications | Cat. No. | Product |
|---|---|---|---|
| Lentiviral Vector & Virus | Stable overexpression | LC631414 | View Product |
| AAV Vector & Virus | Long-term expression | VC631414 | View Product |
| Adenovirus | Transient expression | A631414 | View Product |
| CRISPR KO Tools | Gene knockout (Lentiviral) | LG631414 | View Product |
| Gene knockout (non-viral) | PG631414 | View Product | |
| Gene knockout (AAV) | VG631414 | View Product | |
| CRISPR Activation | Gene activation | LA631414 | View Product |
| siRNA Tools | Gene knockdown (Lentiviral) | LS631414 | View Product |
| Gene knockdown (AAV) | VS631414 | View Product | |
| ORF Vector | Template DNA | PC631414 | View Product |
Accelerate Discovery with Research-Ready Constructs
| Why Researchers Choose abm | Workflow Benefits |
|---|---|
| Gene-Specific Constructs | Eliminate time-consuming cloning and accelerate project timelines |
| Available as Plasmid DNA or Packaged Virus | Choose delivery format that best fits your experiment |
| Validated Sequence Design | Ensure reliable, reproducible experimental performance |
| Available in Multiple Species Options | Simplify cross-species and translational research studies |
| Flexible Customization Services | Tailor constructs with different promoters, tags, markers and other modifications |
| Expert Technical Support | Get guidance from gene delivery specialists |
Product Overview & Key Features
| System | Applications | Key Features |
|---|---|---|
| CRISPR Knockout Vectors & Viruses | Targeted gene disruption & functional knockout studies | •Pre-designed validated sgRNAs •Available in All-in-One Cas9 + sgRNA or sgRNA-only formats •Available as lentivirus, AAV and non-viral •Ideal for stable genome editing |
| Lentiviral Expression Vectors & Particles | Stable gene overexpression or delivery into difficult-to-transfect cells | •Long-term expression through genomic integration •Highly efficient in dividing and non-dividing cells •Ideal for stable cell line generation |
| AAV Vectors & Packaged Virus | In vivo delivery & transient expression with low immunogenicity | •Multiple serotypes available for tissue targeting •Excellent for animal studies and sensitive primary cells •Episomal expression with strong safety profile |
| Adenovirus | High-efficiency transient expression | •Rapid, robust gene expression •Large cargo capacity •Ideal for primary cells and strong short-term expression studies |
| ORF Vector | Template for coding sequence | •Ready-to-use full-length coding sequences •Low cost and convenient alternative to gene synthesis |
| siRNA Knockdown Tools | Temporary gene silencing & pathway validation | •Robust gene knockdown •Ideal for target validation and preliminary functional screening •Available as Lentivirus, AAV or synthetic dsRNA oligos |