NFE2 Expression Vectors, Lentivirus & CRISPR Knockout Vectors
Enhance your research with ready-to-use NFE2-specific vectors and viral particles designed for reliable NFE2 overexpression, knockout, and silencing across a wide range of experimental systems. abm offers a complete portfolio of validated molecular tools – including NFE2 CRISPR knockout vectors, lentiviral particles, AAV vectors, adenovirus, ORF clones, and siRNA constructs for both in vitro and in vivo applications.
Human NFE2 Gene Overview
| Gene Name | nuclear factor, erythroid 2 |
|---|---|
| Gene Symbol | NFE2 |
| Synonyms | p45,NF-E2 |
| NCBI ID | 4778 |
| Ensembl ID | ENSG00000123405 |
| Uniprot ID | Q16621 |
| Gene Type | Protein coding |
Gene Summary
Enables WW domain binding activity; identical protein binding activity; and sequence-specific double-stranded DNA binding activity. Contributes to cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to act upstream of or within several processes, including labyrinthine layer blood vessel development; negative regulation of bone mineralization; and positive regulation of peptidyl-lysine acetylation. Part of RNA polymerase II transcription regulator complex and protein-DNA complex. [provided by Alliance of Genome Resources, Jul 2025]
Human NFE2 Related Products
| Product Type | Key Applications | Cat. No. | Product |
|---|---|---|---|
| Lentiviral Vector & Virus | Stable overexpression | LC231766 | View Product |
| AAV Vector & Virus | Long-term expression | VC131766 | View Product |
| Adenovirus | Transient expression | A131766 | View Product |
| CRISPR KO Tools | Gene knockout (Lentiviral) | LG131766 | View Product |
| Gene knockout (non-viral) | PG131766 | View Product | |
| Gene knockout (AAV) | VG131766 | View Product | |
| CRISPR Activation | Gene activation | LA131766 | View Product |
| siRNA Tools | Gene knockdown (Lentiviral) | LS131766 | View Product |
| Gene knockdown (AAV) | VS131766 | View Product | |
| ORF Vector | Template DNA | PC131766 | View Product |
Mouse Nf2 Gene Overview
| Gene Name | neurofibromin 2 |
|---|---|
| Gene Symbol | Nf2 |
| Synonyms | merlin |
| NCBI ID | 18016 |
| Ensembl ID | ENSMUSG00000009073 |
| Uniprot ID | P46662 |
| Gene Type | Protein coding |
Gene Summary
Predicted to enable several functions, including actin binding activity; beta-catenin binding activity; and integrin binding activity. Involved in lens fiber cell differentiation. Acts upstream of or within several processes, including hippocampus development; negative regulation of cell population proliferation; and negative regulation of protein kinase activity. Located in several cellular components, including adherens junction; cleavage furrow; and ruffle. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; respiratory system; and sensory organ. Used to study coloboma; otitis media; renal cell carcinoma; and vestibular schwannomatosis. Human ortholog(s) of this gene implicated in gastrointestinal system cancer (multiple); malignant pleural mesothelioma; meningioma (multiple); neurilemmoma; and vestibular schwannomatosis. Orthologous to human NF2 (NF2, moesin-ezrin-radixin like (MERLIN) tumor suppressor). [provided by Alliance of Genome Resources, Jul 2025]
Mouse Nf2 Related Products
| Product Type | Key Applications | Cat. No. | Product |
|---|---|---|---|
| Lentiviral Vector & Virus | Stable overexpression | LC431766 | View Product |
| AAV Vector & Virus | Long-term expression | VC431766 | View Product |
| Adenovirus | Transient expression | A431766 | View Product |
| CRISPR KO Tools | Gene knockout (Lentiviral) | LG431766 | View Product |
| Gene knockout (non-viral) | PG431766 | View Product | |
| Gene knockout (AAV) | VG431766 | View Product | |
| CRISPR Activation | Gene activation | LA431766 | View Product |
| siRNA Tools | Gene knockdown (Lentiviral) | LS431766 | View Product |
| Gene knockdown (AAV) | VS431766 | View Product | |
| ORF Vector | Template DNA | PC431766 | View Product |
Rat Nfe2 Gene Overview
| Gene Name | nuclear factor, erythroid 2 |
|---|---|
| Gene Symbol | Nfe2 |
| Synonyms | |
| NCBI ID | 366998 |
| Ensembl ID | ENSRNOG00000036837 |
| Uniprot ID | Q6AYT2 |
| Gene Type | Protein coding |
Gene Summary
Predicted to enable several functions, including RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; WW domain binding activity; and identical protein binding activity. Predicted to contribute to cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to act upstream of or within several processes, including labyrinthine layer blood vessel development; negative regulation of bone mineralization; and positive regulation of peptidyl-lysine acetylation. Predicted to be located in PML body and cytoplasm. Predicted to be part of RNA polymerase II transcription regulator complex and protein-DNA complex. Predicted to be active in nucleus. Orthologous to human NFE2 (nuclear factor, erythroid 2). [provided by Alliance of Genome Resources, Jul 2025]
Rat Nfe2 Related Products
| Product Type | Key Applications | Cat. No. | Product |
|---|---|---|---|
| Lentiviral Vector & Virus | Stable overexpression | LC631766 | View Product |
| AAV Vector & Virus | Long-term expression | VC631766 | View Product |
| Adenovirus | Transient expression | A631766 | View Product |
| CRISPR KO Tools | Gene knockout (Lentiviral) | LG631766 | View Product |
| Gene knockout (non-viral) | PG631766 | View Product | |
| Gene knockout (AAV) | VG631766 | View Product | |
| CRISPR Activation | Gene activation | LA631766 | View Product |
| siRNA Tools | Gene knockdown (Lentiviral) | LS631766 | View Product |
| Gene knockdown (AAV) | VS631766 | View Product | |
| ORF Vector | Template DNA | PC631766 | View Product |
Accelerate Discovery with Research-Ready Constructs
| Why Researchers Choose abm | Workflow Benefits |
|---|---|
| Gene-Specific Constructs | Eliminate time-consuming cloning and accelerate project timelines |
| Available as Plasmid DNA or Packaged Virus | Choose delivery format that best fits your experiment |
| Validated Sequence Design | Ensure reliable, reproducible experimental performance |
| Available in Multiple Species Options | Simplify cross-species and translational research studies |
| Flexible Customization Services | Tailor constructs with different promoters, tags, markers and other modifications |
| Expert Technical Support | Get guidance from gene delivery specialists |
Product Overview & Key Features
| System | Applications | Key Features |
|---|---|---|
| CRISPR Knockout Vectors & Viruses | Targeted gene disruption & functional knockout studies | •Pre-designed validated sgRNAs •Available in All-in-One Cas9 + sgRNA or sgRNA-only formats •Available as lentivirus, AAV and non-viral •Ideal for stable genome editing |
| Lentiviral Expression Vectors & Particles | Stable gene overexpression or delivery into difficult-to-transfect cells | •Long-term expression through genomic integration •Highly efficient in dividing and non-dividing cells •Ideal for stable cell line generation |
| AAV Vectors & Packaged Virus | In vivo delivery & transient expression with low immunogenicity | •Multiple serotypes available for tissue targeting •Excellent for animal studies and sensitive primary cells •Episomal expression with strong safety profile |
| Adenovirus | High-efficiency transient expression | •Rapid, robust gene expression •Large cargo capacity •Ideal for primary cells and strong short-term expression studies |
| ORF Vector | Template for coding sequence | •Ready-to-use full-length coding sequences •Low cost and convenient alternative to gene synthesis |
| siRNA Knockdown Tools | Temporary gene silencing & pathway validation | •Robust gene knockdown •Ideal for target validation and preliminary functional screening •Available as Lentivirus, AAV or synthetic dsRNA oligos |