NKX6-1 Expression Vectors, Lentivirus & CRISPR Knockout Vectors
Enhance your research with ready-to-use NKX6-1-specific vectors and viral particles designed for reliable NKX6-1 overexpression, knockout, and silencing across a wide range of experimental systems. abm offers a complete portfolio of validated molecular tools – including NKX6-1 CRISPR knockout vectors, lentiviral particles, AAV vectors, adenovirus, ORF clones, and siRNA constructs for both in vitro and in vivo applications.
Human NKX6-1 Gene Overview
| Gene Name | NK6 homeobox 1 |
|---|---|
| Gene Symbol | NKX6-1 |
| Synonyms | NKX6A,NKX6.1 |
| NCBI ID | 4825 |
| Ensembl ID | ENSG00000163623 |
| Uniprot ID | P78426 |
| Gene Type | Protein coding |
Gene Summary
In the pancreas, NKX6.1 is required for the development of beta cells and is a potent bifunctional transcription regulator that binds to AT-rich sequences within the promoter region of target genes Iype et al. (2004) [PubMed 15056733].[supplied by OMIM, Mar 2008]
Human NKX6-1 Related Products
| Product Type | Key Applications | Cat. No. | Product |
|---|---|---|---|
| Lentiviral Vector & Virus | Stable overexpression | LC131890 | View Product |
| AAV Vector & Virus | Long-term expression | VC131890 | View Product |
| Adenovirus | Transient expression | A131890 | View Product |
| CRISPR KO Tools | Gene knockout (Lentiviral) | LG131890 | View Product |
| Gene knockout (non-viral) | PG131890 | View Product | |
| Gene knockout (AAV) | VG131890 | View Product | |
| CRISPR Activation | Gene activation | LA131890 | View Product |
| siRNA Tools | Gene knockdown (Lentiviral) | LS131890 | View Product |
| Gene knockdown (AAV) | VS131890 | View Product | |
| ORF Vector | Template DNA | PC131890 | View Product |
Mouse Nkx6-1 Gene Overview
| Gene Name | NK6 homeobox 1 |
|---|---|
| Gene Symbol | Nkx6-1 |
| Synonyms | NKX6A,Nkx6.1 |
| NCBI ID | 18096 |
| Ensembl ID | ENSMUSG00000035187 |
| Uniprot ID | Q99MA9 |
| Gene Type | Protein coding |
Gene Summary
Predicted to enable DNA-binding transcription repressor activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and chromatin binding activity. Acts upstream of or within several processes, including endocrine pancreas development; regulation of oligodendrocyte differentiation; and spinal cord motor neuron cell fate specification. Located in nucleus. Is expressed in several structures, including central nervous system; future brain; gut; and trachea. Orthologous to human NKX6-1 (NK6 homeobox 1). [provided by Alliance of Genome Resources, Jul 2025]
Mouse Nkx6-1 Related Products
| Product Type | Key Applications | Cat. No. | Product |
|---|---|---|---|
| Lentiviral Vector & Virus | Stable overexpression | LC431890 | View Product |
| AAV Vector & Virus | Long-term expression | VC431890 | View Product |
| Adenovirus | Transient expression | A431890 | View Product |
| CRISPR KO Tools | Gene knockout (Lentiviral) | LG431890 | View Product |
| Gene knockout (non-viral) | PG431890 | View Product | |
| Gene knockout (AAV) | VG431890 | View Product | |
| CRISPR Activation | Gene activation | LA431890 | View Product |
| siRNA Tools | Gene knockdown (Lentiviral) | LS431890 | View Product |
| Gene knockdown (AAV) | VS431890 | View Product | |
| ORF Vector | Template DNA | PC431890 | View Product |
Rat Nkx6-1 Gene Overview
| Gene Name | NK6 homeobox 1 |
|---|---|
| Gene Symbol | Nkx6-1 |
| Synonyms | Nkx61,Nkx6a,Nkx6.1 |
| NCBI ID | 65193 |
| Ensembl ID | ENSRNOG00000002149 |
| Uniprot ID | O35762 |
| Gene Type | Protein coding |
Gene Summary
Enables DNA-binding transcription repressor activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and chromatin binding activity. Involved in several processes, including positive regulation of insulin secretion; type B pancreatic cell development; and type B pancreatic cell proliferation. Predicted to be active in nucleus. Orthologous to human NKX6-1 (NK6 homeobox 1). [provided by Alliance of Genome Resources, Jul 2025]
Rat Nkx6-1 Related Products
| Product Type | Key Applications | Cat. No. | Product |
|---|---|---|---|
| Lentiviral Vector & Virus | Stable overexpression | LC631890 | View Product |
| AAV Vector & Virus | Long-term expression | VC631890 | View Product |
| Adenovirus | Transient expression | A631890 | View Product |
| CRISPR KO Tools | Gene knockout (Lentiviral) | LG631890 | View Product |
| Gene knockout (non-viral) | PG631890 | View Product | |
| Gene knockout (AAV) | VG631890 | View Product | |
| CRISPR Activation | Gene activation | LA631890 | View Product |
| siRNA Tools | Gene knockdown (Lentiviral) | LS631890 | View Product |
| Gene knockdown (AAV) | VS631890 | View Product | |
| ORF Vector | Template DNA | PC631890 | View Product |
Accelerate Discovery with Research-Ready Constructs
| Why Researchers Choose abm | Workflow Benefits |
|---|---|
| Gene-Specific Constructs | Eliminate time-consuming cloning and accelerate project timelines |
| Available as Plasmid DNA or Packaged Virus | Choose delivery format that best fits your experiment |
| Validated Sequence Design | Ensure reliable, reproducible experimental performance |
| Available in Multiple Species Options | Simplify cross-species and translational research studies |
| Flexible Customization Services | Tailor constructs with different promoters, tags, markers and other modifications |
| Expert Technical Support | Get guidance from gene delivery specialists |
Product Overview & Key Features
| System | Applications | Key Features |
|---|---|---|
| CRISPR Knockout Vectors & Viruses | Targeted gene disruption & functional knockout studies | •Pre-designed validated sgRNAs •Available in All-in-One Cas9 + sgRNA or sgRNA-only formats •Available as lentivirus, AAV and non-viral •Ideal for stable genome editing |
| Lentiviral Expression Vectors & Particles | Stable gene overexpression or delivery into difficult-to-transfect cells | •Long-term expression through genomic integration •Highly efficient in dividing and non-dividing cells •Ideal for stable cell line generation |
| AAV Vectors & Packaged Virus | In vivo delivery & transient expression with low immunogenicity | •Multiple serotypes available for tissue targeting •Excellent for animal studies and sensitive primary cells •Episomal expression with strong safety profile |
| Adenovirus | High-efficiency transient expression | •Rapid, robust gene expression •Large cargo capacity •Ideal for primary cells and strong short-term expression studies |
| ORF Vector | Template for coding sequence | •Ready-to-use full-length coding sequences •Low cost and convenient alternative to gene synthesis |
| siRNA Knockdown Tools | Temporary gene silencing & pathway validation | •Robust gene knockdown •Ideal for target validation and preliminary functional screening •Available as Lentivirus, AAV or synthetic dsRNA oligos |