NOD1 Expression Vectors, Lentivirus & CRISPR Knockout Vectors
Enhance your research with ready-to-use NOD1-specific vectors and viral particles designed for reliable NOD1 overexpression, knockout, and silencing across a wide range of experimental systems. abm offers a complete portfolio of validated molecular tools – including NOD1 CRISPR knockout vectors, lentiviral particles, AAV vectors, adenovirus, ORF clones, and siRNA constructs for both in vitro and in vivo applications.
Human NOD1 Gene Overview
| Gene Name | nucleotide binding oligomerization domain containing 1 |
|---|---|
| Gene Symbol | NOD1 |
| Synonyms | CARD4,NLRC1,hNod1,CLR7.1 |
| NCBI ID | 10392 |
| Ensembl ID | ENSG00000106100 |
| Uniprot ID | Q9Y239 |
| Gene Type | Protein coding |
Gene Summary
This gene encodes a member of the nucleotide-binding oligomerization domain (NOD)-like receptor (NLR) family of proteins. The encoded protein plays a role in innate immunity by acting as a pattern-recognition receptor (PRR) that binds bacterial peptidoglycans and initiates inflammation. This protein has also been implicated in the immune response to viral and parasitic infection. Major structural features of this protein include an N-terminal caspase recruitment domain (CARD), a centrally located nucleotide-binding domain (NBD), and 10 tandem leucine-rich repeats (LRRs) in its C terminus. The CARD is involved in apoptotic signaling, LRRs participate in protein-protein interactions, and mutations in the NBD may affect the process of oligomerization and subsequent function of the LRR domain. Mutations in this gene are associated with asthma, inflammatory bowel disease, Behcet disease and sarcoidosis in human patients. [provided by RefSeq, Aug 2017]
Human NOD1 Related Products
| Product Type | Key Applications | Cat. No. | Product |
|---|---|---|---|
| Lentiviral Vector & Virus | Stable overexpression | LC131975 | View Product |
| AAV Vector & Virus | Long-term expression | VC131975 | View Product |
| Adenovirus | Transient expression | A231975 | View Product |
| CRISPR KO Tools | Gene knockout (Lentiviral) | LG131975 | View Product |
| Gene knockout (non-viral) | PG131975 | View Product | |
| Gene knockout (AAV) | VG131975 | View Product | |
| CRISPR Activation | Gene activation | LA131975 | View Product |
| siRNA Tools | Gene knockdown (Lentiviral) | LS131975 | View Product |
| Gene knockdown (AAV) | VS131975 | View Product | |
| ORF Vector | Template DNA | PC131975 | View Product |
Mouse Nod1 Gene Overview
| Gene Name | nucleotide-binding oligomerization domain containing 1 |
|---|---|
| Gene Symbol | Nod1 |
| Synonyms | Card4,Nlrc1,mNod1,C230079P11,F830007N14Rik |
| NCBI ID | 107607 |
| Ensembl ID | ENSMUSG00000038058 |
| Uniprot ID | Q8BHB0 |
| Gene Type | Protein coding |
Gene Summary
Enables pattern recognition receptor activity and peptidoglycan binding activity. Involved in several processes, including nucleotide-binding activity oligomerization domain containing 1 signaling pathway; positive regulation of canonical NF-kappaB signal transduction; and positive regulation of dendritic cell antigen processing and presentation. Acts upstream of or within several processes, including positive regulation of MAPK cascade; positive regulation of cytokine production; and positive regulation of xenophagy. Located in phagocytic vesicle. Is expressed in several structures, including alimentary system; autopod; brain; olfactory epithelium; and urinary system. Human ortholog(s) of this gene implicated in asthma. Orthologous to human NOD1 (nucleotide binding oligomerization domain containing 1). [provided by Alliance of Genome Resources, Jul 2025]
Mouse Nod1 Related Products
| Product Type | Key Applications | Cat. No. | Product |
|---|---|---|---|
| Lentiviral Vector & Virus | Stable overexpression | LC431975 | View Product |
| Stable overexpression | LC531975 | View Product | |
| AAV Vector & Virus | Long-term expression | VC431975 | View Product |
| Long-term expression | VC531975 | View Product | |
| Adenovirus | Transient expression | A431975 | View Product |
| Transient expression | A531975 | View Product | |
| CRISPR KO Tools | Gene knockout (Lentiviral) | LG431975 | View Product |
| Gene knockout (non-viral) | PG431975 | View Product | |
| Gene knockout (AAV) | VG431975 | View Product | |
| CRISPR Activation | Gene activation | LA431975 | View Product |
| siRNA Tools | Gene knockdown (Lentiviral) | LS431975 | View Product |
| Gene knockdown (AAV) | VS431975 | View Product | |
| ORF Vector | Template DNA | PC431975 | View Product |
| Template DNA | PC531975 | View Product |
Rat Nod1 Gene Overview
| Gene Name | nucleotide-binding oligomerization domain containing 1 |
|---|---|
| Gene Symbol | Nod1 |
| Synonyms | Card4,RGD1562269 |
| NCBI ID | 500133 |
| Ensembl ID | ENSRNOG00000010629 |
| Uniprot ID | |
| Gene Type | Protein coding |
Gene Summary
Predicted to enable several functions, including CARD domain binding activity; peptidoglycan binding activity; and protein homodimerization activity. Involved in positive regulation of apoptotic process; positive regulation of cytokine production; and positive regulation of nitric-oxide synthase activity. Predicted to be located in basolateral plasma membrane; cytosol; and phagocytic vesicle. Predicted to be part of canonical inflammasome complex. Predicted to be active in plasma membrane. Human ortholog(s) of this gene implicated in asthma. Orthologous to human NOD1 (nucleotide binding oligomerization domain containing 1). [provided by Alliance of Genome Resources, Jul 2025]
Rat Nod1 Related Products
| Product Type | Key Applications | Cat. No. | Product |
|---|---|---|---|
| Lentiviral Vector & Virus | Stable overexpression | LC631975 | View Product |
| AAV Vector & Virus | Long-term expression | VC631975 | View Product |
| Adenovirus | Transient expression | A631975 | View Product |
| CRISPR KO Tools | Gene knockout (Lentiviral) | LG631975 | View Product |
| Gene knockout (non-viral) | PG631975 | View Product | |
| Gene knockout (AAV) | VG631975 | View Product | |
| CRISPR Activation | Gene activation | LA631975 | View Product |
| siRNA Tools | Gene knockdown (Lentiviral) | LS631975 | View Product |
| Gene knockdown (AAV) | VS631975 | View Product | |
| ORF Vector | Template DNA | PC631975 | View Product |
Accelerate Discovery with Research-Ready Constructs
| Why Researchers Choose abm | Workflow Benefits |
|---|---|
| Gene-Specific Constructs | Eliminate time-consuming cloning and accelerate project timelines |
| Available as Plasmid DNA or Packaged Virus | Choose delivery format that best fits your experiment |
| Validated Sequence Design | Ensure reliable, reproducible experimental performance |
| Available in Multiple Species Options | Simplify cross-species and translational research studies |
| Flexible Customization Services | Tailor constructs with different promoters, tags, markers and other modifications |
| Expert Technical Support | Get guidance from gene delivery specialists |
Product Overview & Key Features
| System | Applications | Key Features |
|---|---|---|
| CRISPR Knockout Vectors & Viruses | Targeted gene disruption & functional knockout studies | •Pre-designed validated sgRNAs •Available in All-in-One Cas9 + sgRNA or sgRNA-only formats •Available as lentivirus, AAV and non-viral •Ideal for stable genome editing |
| Lentiviral Expression Vectors & Particles | Stable gene overexpression or delivery into difficult-to-transfect cells | •Long-term expression through genomic integration •Highly efficient in dividing and non-dividing cells •Ideal for stable cell line generation |
| AAV Vectors & Packaged Virus | In vivo delivery & transient expression with low immunogenicity | •Multiple serotypes available for tissue targeting •Excellent for animal studies and sensitive primary cells •Episomal expression with strong safety profile |
| Adenovirus | High-efficiency transient expression | •Rapid, robust gene expression •Large cargo capacity •Ideal for primary cells and strong short-term expression studies |
| ORF Vector | Template for coding sequence | •Ready-to-use full-length coding sequences •Low cost and convenient alternative to gene synthesis |
| siRNA Knockdown Tools | Temporary gene silencing & pathway validation | •Robust gene knockdown •Ideal for target validation and preliminary functional screening •Available as Lentivirus, AAV or synthetic dsRNA oligos |